DNA Replication Flashcards
2 ways DNA is used
- template to copy itself during DNA replication
2. converts to RNA (transcription)/ RNA used to make protein (translation)
interphase
non dividing stage of cell cycle
3 stages of interphase
G1- cells produced by cell division grow and prepare for DNA replication
S- synthesis; DNA replicated
G2 cells prepare to divide
DNA monomer
nucleotide
3 parts of nucleotide
- deoxyribose sugar
- phosphate group
- nitrogen base
4 nitrogen bases in DNA
adenine, thymine, cytosine, guanine
semiconservative replication
each double strand has 1 old strand and one new
DNA helicase
unwinds and separates strands of double helix
DNA polymerase
- finds origin of replication
- forms replication bubble and moves forks along template strand
- adds nucleotides to new DNA strand
DNA ligase
connects new DNA pieces together into one strand
leading strand
oriented properly for enzyme to read
synthesized continuously
lagging strand
oriented backward
synthesized in Okazaki fragments, joined by DNA ligase
chromatin
invisible, non dividing form of DNA
chromosomes
visible DNA
DNA twists around histones, becomes shorter and thicker, eventually visible