dna and mitotic cycle Flashcards

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1
Q

semi-conservative replication

A

each time DNA is replicated half of the original molecule is kept in each new molecules

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2
Q

steps of DNA replication

A

1 unwinding, dna helices breaking hydrogen bonds
2 dna polymerase for copying process adding nucleotides
3 leading strand replicated continuously in 3’ to 5’
lagging strand replicated discontinuously in 5’ to 3’ direction In short sections making Okazaki fragments

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3
Q

nucleotides are joined by

A

phosphodiester bonds

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4
Q

what phase does dna replication occur in

A

s phase

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5
Q

rna polymerase is used in

A

transcription

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6
Q

what are Okazaki fragments joined by

A

DNA ligase

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7
Q

purines

A

double ring structure
adenine
guanine

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8
Q

semi conservative replication is good because

A

it ensure genetic continuity between generations

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9
Q

lagging strand

A

runs in the 5’ to 3’ direction

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10
Q

transcription

A

1 rna polymerase attaches to start of gene and unwinds gene
2 template/transcribes strand is copied
3 nucleotides approach and hydrogen bond with complementary bases +phosphodiester bonds to growing mrna hydrogen broken
mana leaves through nuclear pore

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11
Q

translation

A

tuna transfer amino acids to ribosome anticodon on tRNA complementry to codon

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12
Q

modifying mrna

A

rna processing
rna splicing removes introns and exons joined together
introns help dna regulate activity of genes

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13
Q

alternative splicing

A

results in different Mrnas ebbing made from original primary transcript meaning. that one gene can code for several proteins or diff forms of same protein

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14
Q

gene mutation

A

change in sequence of bases can result in different sequence of amino acid

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15
Q

chromosome mutation

A

Chromosome structure mutations are alterations that affect whole chromosomes and whole genes rather than just individual nucleotides. These mutations result from errors in cell division that cause a section of a chromosome to break off, be duplicated or move onto another chromosome.

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16
Q

stop codons

A

UAG, UAA, UGA

17
Q

start codon

A

AUG amino acid methionine

18
Q

2 things in early prophase

A

nuclear envelope breaks down
chromosome condense

19
Q

2 things in late prophase

A

chromosomes migrate to opposite poles of cell
spindle fibres from

20
Q

2 things in metaphase

A

chromosomes line up along equator
spindle fibres attach to kinetochores

21
Q

kinetochore

A

protein structure found at centromere where microtubules attach

22
Q

3 things in anaphase

A

chromatids separate
spindle fibres attach to centrosome
poles of cell move apart

23
Q

3 things in telophase

A

chromosomes begin to uncoil
nuclear envelope reforms
spindles disappear

24
Q

telomere

A

a repetitive sequence of DNA at the end of a chromosome that protects genes from the chromosome shortening at each cell division

25
Q

oncogene

A

mutated gene that has the potential to cause cancer.

26
Q

transcription

A

genetic code on DNA is copied into mRNA;
double helix of DNA unwinds (in region to be copied); complementary nucleotides line up along coding strand of DNA; A to U and C to G;
assemble together to make a complementary strand of mRNA; under influence of RNA polymerase;
mRNA unzips from DNA template and passes to ribosomes;

27
Q

translation

A