dna and mitotic cycle Flashcards
semi-conservative replication
each time DNA is replicated half of the original molecule is kept in each new molecules
steps of DNA replication
1 unwinding, dna helices breaking hydrogen bonds
2 dna polymerase for copying process adding nucleotides
3 leading strand replicated continuously in 3’ to 5’
lagging strand replicated discontinuously in 5’ to 3’ direction In short sections making Okazaki fragments
nucleotides are joined by
phosphodiester bonds
what phase does dna replication occur in
s phase
rna polymerase is used in
transcription
what are Okazaki fragments joined by
DNA ligase
purines
double ring structure
adenine
guanine
semi conservative replication is good because
it ensure genetic continuity between generations
lagging strand
runs in the 5’ to 3’ direction
transcription
1 rna polymerase attaches to start of gene and unwinds gene
2 template/transcribes strand is copied
3 nucleotides approach and hydrogen bond with complementary bases +phosphodiester bonds to growing mrna hydrogen broken
mana leaves through nuclear pore
translation
tuna transfer amino acids to ribosome anticodon on tRNA complementry to codon
modifying mrna
rna processing
rna splicing removes introns and exons joined together
introns help dna regulate activity of genes
alternative splicing
results in different Mrnas ebbing made from original primary transcript meaning. that one gene can code for several proteins or diff forms of same protein
gene mutation
change in sequence of bases can result in different sequence of amino acid
chromosome mutation
Chromosome structure mutations are alterations that affect whole chromosomes and whole genes rather than just individual nucleotides. These mutations result from errors in cell division that cause a section of a chromosome to break off, be duplicated or move onto another chromosome.