DMT Flashcards
DMT is used therapeutically how?
Insight-oriented psychotherapy
- PTSD, phobia, Anxiety (Rationalization: cognitive restructuring based on logic)
- removing/changing the emotional component
Depression addiction
-theraputic (insight)
Where is DMT found?
Tree bark
What is it structurally similar to?
serotonin
implies similar transport and enzymatic functions
also functionally similar to psylocibin
What is the Structure-activity relationship?
relationship between a chemical’s structure and biological activity
(modification(of structure) allows for changes in effectiveness of potency
Where is the enzyme that is used to break down DMT found?
found in the body ONLY not in the brain
What are tryptamines naturally synthesized into?
serotonin
In the first stage of DMT working as an agonist what happens? (NT’s, SOA, Effect)
Dopamine
Insula
auditory hallucinations (crackling/extending tone that increases in volume and pitch)
In the second stage of DMT working as an agonist what happens? (NT’s, SOA, Effect)
Dopamine
amygdala
Waiting room (animated suspension (physical “fear” response)
-increased heart rate
psychological “startle” response
slow motion waiting loss of time
In the third stage of DMT working as an agonist what happens? (NT’s, SOA, Effect)
Serotonin
prefrontal cortex
DMT hyperspace (otherside)
machine elves (presence of humanoid like half organic half technological beings may speak different languages that are understandable
Intake of DMT?
inhalation, injection
What is the problem with ingestion of DMT?
What is the solution?
MAO enzyme deactivates/breaks down DMT molecule in liver
provide MAO inhibitor (MAO-I)
Ayhausca : brew which includes plant derived DMT, Harmine, Tetrahydroharmine
this results in longer high 3-6 hours
DMT tolerance?
No tolerance
