DM med review Flashcards
What type of drug is glipizide? MOA? Side effect?
- Sulfonylurea
- Increases endogenous insulin production
- Hypoglycemia and weight gain
What type of drug is glyburide? MOA? Side effect?
- Sulfonylurea
- Increases endogenous insulin production
- Hypoglycemia and weight gain
What type of drug is glimepiride? MOA? Side effect?
- Sulfonylurea
- Increases endogenous insulin production
- Hypoglycemia and weight gain
What type of drug is Metformin? MOA? Side effect? Contraindications?
-biguanide
inhibits gluconeogenesis and increases insulin sensitivity
-weight loss
-renal insufficiency
What type of drug is rosiglitazone? MOA? Side effect? Contraindications?
- thiazolidinedione
- Increases insulin sensitivity
- Can cause edema
- Contraindicated in HF
What type of drug is pioglitazone? MOA? Side effect? Contraindications?
- thiazolidinedione
- Increases insulin sensitivity
- Can cause edema
- Contraindicated in HF
What type of drug are the -gliptins? MOA? Side effect?
- DPP-4 inhibitor
- inhibits degradation of GLP-1
- Weight neutral
What type of drug are the -tides? MOA? Side effect?
- incretins
- GLP-1 agonist, delaying absorption of food
- Causes weight loss and is an injectiable
What type of drug are the -flozins? MOA? Side effect?
- Inhibits SGL2 in proximal tubule to decrease glucose absorption
- Can cause UTIs, weight loss
What are the first line agents for BP control in DM pts?
ACEIs/ARBs
What are the weight neutral DM medications?
DPP-4 inhibitors
-gliptins
What DM medication can cause weight gain?
Sulfonylureas
What are the three major sulfonylureas?
- Glipizide
- Glyburide
- Glimepiride
What is the MOA and side effect of the alpha-glucosidase inhibitors?
- Decreases intestinal absorption of carbs
- Flatulence and diarrhea
