diuretics (thiazide)

Question 1

Indications of diuretics

Answer 1

oedema, hypertension

Question 2

Contraindications of diuretics

Answer 2

hyponatraemia, refractory hypokalaemia, symptomatic hyperuricaemia, hypercalcaemia, addisons disease

Question 3

Mechanism of action of diuretics

Answer 3

inhibits the renal tubular absorption of salt and water and reduces the absorption of electrolytes by its action at the beginning of the distal convoluted tubule. this increases the excretion of sodium and chloride ions and consequently of water. hypotensive effect is due to reduction in peripheral resistance

Question 4

Side effect of diuretics

Answer 4

altered plasma-lipid concentrations, gout, hypercalcaemia, hyperglycaemia, hyperuricaemia, hypochloraemia alkalosis, hypokalaemia, hypomagnesaemia, hyponatraemia

Question 5

Monitoring requirements of diuretics

Answer 5

monitor electrolytes

Question 6

Treatment cessation of diuretics

Answer 6

none

Question 7

Patient and carer advice for diuretics

Answer 7

monitor biochemistry