5HT3 antagonists - antiemetics Flashcards by Georgina Latham | Brainscape

Q

Indications for 5HT3 antagonists

A

good for chemotherapy/radiotherapy

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Q

Contraindications for 5HT3 antagonists

A

congenital long QT syndrome

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Q

Mechanism of action of 5HT3 antagonists

A

competitive antagonist of 5HT3 (serotonin) receptors in the gastrointestinal tract and the central nervous system to slow gut motility, works at the chemotrigger zone to prevent initiation of vomiting

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Q

Side effects of 5HT3 antagonists

A

constipation, flushing, headache, diarrhoea, insomnia, injection site reactions

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Q

Monitoring requirements for 5HT3 antagonists

A

none

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Q

Treatment cessation for 5HT3 antagonists

A

none

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Q

Patient and carer advice for 5HT3 antagonists

A

advice on how to properly administer

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