antiplatelets (aspirin)

Question 1

Indications of aspirin

Answer 1

cardiovascular disease, ischaemic attack/stroke, angina, reduce risk of stroke or myocardial infarction

Question 2

Contra-indications of aspirin

Answer 2

haemophilia, bleeding disorders, children under 16 (Reyes syndrome), severe cardiac failure, previous/active peptic ulceration

Question 3

Mechanism of action of aspirin

Answer 3

inhibits the cyclooxygenase enzyme which suppresses the production of prostaglandins and thromboxanes, this decreases platelet aggregation and inhibits thrombus formation

Question 4

Common side effects of aspirin

Answer 4

gastrointestinal irritation/discomfort, nausea, increased bleeding, tinnitus, vertigo, confusion

Question 5

Monitoring requirements for aspirin

Answer 5

none

Question 6

Treatment cessation for aspirin

Answer 6

none

Question 7

Patient and carer advice for aspirin

Answer 7

inform patients of increased bleeding and bruising