[Discussion] MODULE 1 UNIT 3 Flashcards
often cause anemia
trypanosomiasis and malaria
can result in bowel obstruction
Ascariasis
can cause diarrhea
amoebiasis
balance between host and parasite is tipped in favor of the parasite
disease
balance shifts in favor of the hosts ability to inhibit the parasite, the it will be damaged and eliminated
parasite
- refers to the number of parasites in or on the host- determines the likelihood of the parasitic disease.
Parasite Load
- the greater the number of parasite infective stages that enter the host, the greater will be the pathological damage.
Parasite Load
- However, a few parasites that have reproductive phase within the host can also have a considerable effect on the host.
Parasite Load
- reflects the ability of a given parasite to infect a specific organ or sets of organs
Tissue tropism
- after entering the host, the parasite migrates to these parts of the body where conditions are suitable for temporary or permanent residence.
Tissue tropism
infecting all or most organs
tropic
to a given tissue or even to certain tissue niches
restricted
Human African trypanosomiasis (HAT) agents
T. brucei rhodesiense and T. brucei gambiense
parasite remains in the peripheral blood and lymphatic system
First stage of Human African trypanosomiasis (HAT)
parasite crossing into the cerebrospinal fluid and ultimately into the brain parenchyma
Second stage of Human African trypanosomiasis (HAT)
refers to the manner of development of a disease
PATHOGENESIS
robs the host of essential nutrients and substances
Infection
Depleting or denying the host of these leads to (?) and in the process causing damage to surrounding tissues.
malnutrition
- Effects of Malnutrition
stunted growth, wasting, hunger, or more specific signs of micronutrient deficiency.
is more likely to occur in individuals with larger burdens of parasites
Malnutrition
attach to the intestinal mucosa by means of teeth or cutting plates.
Hookworms
Aside from the bleeding at the site of attachment, these parasites ingest human blood, which results in irondeficiency anemia.
Hookworms
prevents absorption of nutrients due to it covering the intestinal mucosa
Giardia lamblia
Physical trauma, or destruction of cells, tissues or organs brought about by parasite attachment, feeding, blockage, or migration by is common in parasite infections.
Traumatic or mechanical damage