[AWISAN] MODULE 3 DISCUSSION Flashcards
Location of Adult in the body
Intestinal nematodes
small intestine
Ascaris, Ancylostoma, Necator, Strongyloides, Trichinella
Location of Adult in the body
Intestinal nematodes
large intestine
Enterobius, Trichuris
Location of Adult in the body
Tissue nematodes
lymphatic:
Wuhereria, Bru gia
Location of Adult in the body
Tissue nematodes
subcutaneous:
Loa loa, Onchocerca, Dracunculus
Location of Adult in the body
Tissue nematodes
mesentery:
Mansonella
Location of Adult in the body
Tissue nematodes
conjunctiva:
Loa loo
Mode of transmission
By ingestion
eggs:
Ascaris, Enterobius, Trichuris
Mode of transmission
By ingestion
larva within IH:
Dracunculus
Mode of transmission
By ingestion
encysted larvae in muscle:
Trichinella
Mode of transmission
By penetration of skin
Ancylostoma, Necator, Strongyloides
Mode of transmission
By blood sucking insects
Filaria
Mode of transmission
By inhalation of dust containing eggs
Ascaris, Enterobius
Mode of attachment
anchorage with their attenuated ends (Trichuris)
oral attachment to the mucosa (Ancylostoma)
penetration of the tissues
(Strongyloides)
retention ¡n the folds of mucosa and pressure against it (Ascaris)
Nourishment
Sucking with ingestion of blood (Ancylostoma)
Ingestion of lysed tissues and blood by enbedded worms (Trichuris) nourishment
Feeding on intestinal contents (Ascaris)
Ingestion of nourishment from body fluid (filarial worm)
Lay eggs or larva
Oviparous: lay eggs
unsegmented:
Ascaris, Trichuris
Lay eggs or larva
Oviparous: lay eggs
segmented:
Ancylostoma, Necator
Lay eggs or larva
Oviparous: lay eggs
egg containing larvae:
Enterobius
Lay eggs or larva
Viviparous: produce larvae
Trichinella, Wuchereria, Brugia, Dracunculus
Lay eggs or larva
Ovoviparous
lay eggs containing fully formed larvae which hatch out immediately
(Strongyloides
Parasite
Whipworm
Trichuris trichiura
Trichuris trichiura
Infective stage
Embryonated ova
Trichuris trichiura
MOT
Ingestion of ova (STH)
Trichuris trichiura
Host
Primarily human
Trichuris trichiura
Habitat
Large intestine; cecum and ascending colon
Trichuris trichiura
Disease
Trichuriasis
Trichoencephalitis
Iron deficiency anemia
Appendicitis
Rectal prolapse
Trichuris trichiura
Diagnostic tool/feature
Stichocytes in adult
Male: coiled ventrally at 3600
“Japanese lantern ova”
Capillary liver worm
Capillaria hepatica
Capillaria hepatica
Infective stage
Embryonated ova
Capillaria hepatica
MOT
Ingestion of ova
Capillaria hepatica
Host
Zoonotic (low host specificity)
Primarily rodent & carnivore
true & spurious infection
Capillaria hepatica
Habitat
Liver parenchyma
Capillaria hepatica
Disease
Hepatic capilliariasis (liver cirrhosis)
rare
Capillaria hepatica
Diagnostic tool/feature
Adult resembles T. trichiura
Lemon-shaped ova
Pudoc worm
Capilliaria philippinensis
Capilliaria philippinensis
Infective stage
Larva
Capilliaria philippinensis
MOT
Ingestion of uncooked fish with infective larva
*internal autoinfection
Capilliaria philippinensis
Host
IH: glassfish (bagsit, bagsang, ipon)
DH: primarily human
Capilliaria philippinensis
Habitat
Small intestinal mucosa
Capilliaria philippinensis
Disease
Mystery disease
Internal Capilliariasis
Malabsorption syndrome (CHON losing enteropathy)
borborygmi
Capilliaria philippinensis
Diagnostic tool/feature
Adult resembles T. trichiura
Larviparous (Autoinfection)
Peanut-shaped ova
Trichina worm
*smallest nematode infecting man
Trichinella spiralis
Trichinella spiralis
Infective stage
Encysted larva
Trichinella spiralis
MOT
Ingestion of undercooked pork
Trichinella spiralis
Host
Vertebrate
domestic cycle
sylvatic cycle
Trichinella spiralis
Habitat
Small intestine
Trichinella spiralis
Disease
Trichinosis
Trichinelliasis
myocarditis, encephalitis
Trichinella spiralis
Diagnostic tool/feature
Muscle biopsy: larva (tightly coiled)
Backman Intradermal Test (hypersensitivity test)
Beck’s Xenodiagnosis
ELISA (recommended)
Western blot & LA (conform ELISA)
Giant kidney worm
Largest nematode infecting man
Dioctophyme/Dyoctophyma renale
Dioctophyme/Dyoctophyma renale
Infective stage
L3 larva
Dioctophyme/Dyoctophyma renale
MOT
Ingestion of uncooked paratenic host with
L3 larva
Dioctophyme/Dyoctophyma renale
Host
IH: aquatic oligochaete worms
(blackworms)
DH: mustelids, canids, otters, martens,
raccoons
*rare in human
Paratenic: freshwater fish and amphibian
Dioctophyme/Dyoctophyma renale
Habitat
Kidney
larva migrate in the subcutaneous nodules
Dioctophyme/Dyoctophyma renale
Disease
Dioctophymiasis (hematuria, abdominal pain, fever, and eopsinophilia)
Dioctophyme/Dyoctophyma renale
Diagnostic tool/feature
Egg in urine, sometime adult
Giant/large intestinal roundworm
largest nematode parasite in the
intestine
Ascaris lumbricoides
Ascaris lumbricoides
Infective stage
Embryonated ova
Ascaris lumbricoides
MOT
Ingestion of embryonated ova
Ascaris lumbricoides
Host
Primarily human
Monkeys/apes
*dogs: spurious
*A. suum: swine
Ascaris lumbricoides
Habitat
Small intestine
Ascaris lumbricoides
Disease
*wandering
Larva: lungs – ascaris pneumonia (Loeffler’s syndrome)
*migrating adult: occlusion of biliary tract, appendicitis, nasopharyngeal
expulsion
Ascaris lumbricoides
Diagnostic tool/feature
Adult mouth: 3 finely denticulated lips
Adult male posterior end: curved ventrally to form a hook with 2 copulatory
spicules
Ova: unfertilized, fertilized, decorticated
Oxyrius vermicularis
Pinworm, seatworm, threadworm
Enterobius vermicularis
Enterobius vermicularis
Infective stage
Embryonated ova
Enterobius vermicularis
MOT
Ingestion of embryonated ova
Inhalation or swallowing of embryonated
ova in dust
*retroinfection
Enterobius vermicularis
Host
Only human: high host specificity
*occasional infection in captive
chimpanzee
*school age
*crowding
Enterobius vermicularis
Habitat
Large intestine
*larva are often found in the appendix but
role in appendicitis is conversial
Enterobius vermicularis
Disease
Enterobiasis
perianal pruritus
vulvovagnitis pelvic or peritoneal granulomas pain that mimics
Enterobius vermicularis
Diagnostic tool/feature
Adult: 3 cephalic alae.
esophagus with double-bulb structure, pointed tail
D-shape ova
Scotch tape method
New world hookworm
American hookworm
American murderer
Necator americanus
Necator americanus
Infective stage
Filariform larvae
Necator americanus
MOT
Skin penetration
Necator americanus
Host
Human
Necator americanus
Habitat
Small intestine (jejunum)
Transpulmonary migration phase
Necator americanus
Disease
Ground itch or coolie itch
Pneumonitis
Iron deficiency anemia (microcytic, hypochromic)
Necator americanus
Diagnostic tool/feature
ovoidal. thin-shelled, colorless
2-8 cell stage ova
Old world hookworm
European hookworm
Germ of lazmesa
Ancylostoma duodenale
Ancylostoma duodenale
Infective stage
Filariform larvae
Ancylostoma duodenale
MOT
Skin penetration
Oral and transmammary route
*Hypobiosis in the intestine or muscle
Ancylostoma duodenale
Host
Human
Ancylostoma duodenale
Habitat
Small intestine (jejunum)
Ancylostoma duodenale
Disease
Ground itch or coolie itch
Pneumonitis
Iron deficiency anemia (microcytic, hypochromic)
Ancylostoma duodenale
Diagnostic tool/feature
ovoidal. thin-shelled, colorless
2-8 cell stage ova
Cat hookworm
Smallest hookworm
Ancylostoma brazlltense
Ancylostoma brazlltense
Infective stage
Filariform larvae
Ancylostoma brazlltense
MOT
Skin penetration
Ancylostoma brazlltense
Host
Zoonotic: canids and felids
Ancylostoma brazlltense
Habitat
Small intestine
Ancylostoma brazlltense
Disease
Cutaneous larva migrans or creeping eruption
Ancylostoma brazlltense
Diagnostic tool/feature
ovoidal. thin-shelled. Colorless
2-8 cell stage ova
dog hookworm
Ancylostoma caninum
Ancylostoma caninum
Infective stage
Filariform larvae
Ancylostoma caninum
MOT
Skin penetration
Oral ingestion
Ancylostoma caninum
Host
Zoonotic:dogs, wolves, cayotes, and
foxes
Ancylostoma caninum
Habitat
Small intestine
Ancylostoma caninum
Disease
Cutaneous larva migrans or creeping eruption
Ancylostoma caninum
Diagnostic tool/feature
ovoidal. thin-shelled, colorless
2-8 cell stage ova
Thread worm
Free living
Strongyloides stercoralis
Strongyloides stercoralis
Infective stage
Filariform larvae
Strongyloides stercoralis
MOT
Skin penetration
Strongyloides stercoralis
Host
Primarily Human
Strongyloides stercoralis
Habitat
Small intestine
Strongyloides stercoralis
Disease
Strongyloidiasis
Larva currens: racing larva
Bronchopneumonia
Chronic bronchitis
Strongyloides stercoralis
Diagnostic tool/feature
ovoidal. thin-shelled, colorless
2-4 cell stage ova
Larva in sputum
3 small lips
partenogenic
dog astrid
Toxocara canis
Toxocara canis
Infective stage
Embryonated ova with L3
Toxocara canis
MOT
ingestion of infective eggs
larva penetration
transplacental & transmammary
Toxocara canis
Host
dog
AH: Human
Toxocara canis
Habitat
Small intestine
Toxocara canis
Disease
Visceral toxocariasis: VLM
Ocular toxocariasis: OLM
- Irreversible blindness
Toxocara canis
Diagnostic tool/feature
Distinct cephalic alae
Longer than broad (bow-like)
Prominent lips
cat astrid
Toxocara catis
Toxocara catis
Infective stage
Embryonated ova with L3
Toxocara catis
MOT
ingestion of infective eggs
larva penetration
transmammary
Toxocara catis
Host
cat
AH: Human
Toxocara catis
Habitat
Small intestine
Toxocara catis
Disease
Visceral toxocariasis: VLM
Ocular toxocariasis: OLM
- Irreversible blindness
Toxocara catis
Diagnostic tool/feature
Distinct cephalic alae
Longer than broad (bow-like)
Prominent lips
rust colored
Gnathostoma spinigerum
Gnathostoma spinigerum
Infective stage
Larvae
Gnathostoma spinigerum
MOT
eating undercooked fish or poultry-larvae
Gnathostoma spinigerum
Host
1
st IH: copepods
2
nd IH: aquatic animals that feed on
copepod (fish, amphibians)
Paratenic: snake, duck
AH: Human
Gnathostoma spinigerum
Habitat
Gastric wall
Gnathostoma spinigerum
Disease
Cutaneous gnathostomiasis/larva migrans profundus (pulmonary, GIT,
genitourinary, auricular, ocular tissues, or CNS)
Neuro-gnathostomiasis
Gnathostoma spinigerum
Diagnostic tool/feature
Prominent cephalic
Bulb and body spines
Rat lungworm
Angiostronglus (Parastrongylus) cantonensis
Angiostronglus (Parastrongylus) cantonensis
Infective stage
Larvae
Angiostronglus (Parastrongylus) cantonensis
MOT
Accidental ingestion of gastropod or larvae
Angiostronglus (Parastrongylus) cantonensis
Host
IH: gastropod (snail or slug)
DH: rats
AH: Human
Angiostronglus (Parastrongylus) cantonensis
Habitat
DH: Pulmonary arteries
*In human, larvae migrate to brain
(occasionally eyes or lungs)
Angiostronglus (Parastrongylus) cantonensis
Disease
Human eosinophilic meningitis (neural angiostrongyliasis)
Ocular angiostrongyliasis
Angiostronglus (Parastrongylus) cantonensis
Diagnostic tool/feature
Eosinophilia
Computed tomography (CT) scan
Magnetic resonance imaging (MRI)
ELISA
Wuchereria bancrofti
Infective stage
3rd stage filarial larvae
Wuchereria bancrofti
MOT
Mosquito bite
Wuchereria bancrofti
Host
DH: Human
IH: Mosquito (Cutex, Aedes, Anopheles)
Wuchereria bancrofti
Habitat
Lymphatics
Wuchereria bancrofti
Disease
elephantiasis of the lower extremities
o Tropical pulmonary eosinophilia
Brugia malayi
Infective stage
3rd stage filarial larvae
Brugia malayi
MOT
Mosquito bite
Brugia malayi
Host
DH: Human
IH: Mosquito (Mansonia, Aedes)
Brugia malayi
Habitat
Lymphatics
Brugia malayi
Disease
elephantiasis of the lower extremities
o Tropical pulmonary eosinophilia
Brugia timori
Infective stage
3rd stage filarial larvae
Brugia timori
MOT
Mosquito bite
Brugia timori
Host
DH: Human
IH: Mosquito (Anopheles)
Brugia timori
Habitat
Lymphatics
Brugia timori
Disease
Mild, than bancroftian or malayan filariasis
African eye worm
Loaloa
Loaloa
Infective stage
3rd stage filarial larvae
Loaloa
MOT
Vector bite
Loaloa
Host
DH: Human
IH: Chrysops
Loaloa
Habitat
Subcutaneous tissue
o Subconjunctival migration of adult
Loaloa
Disease
Calabar swelling (episodic angioedema), fugitive swelling
Loiasis
Onchocerca volvulus
Infective stage
3rd stage filarial larvae
Onchocerca volvulus
MOT
Vector bite
Onchocerca volvulus
Host
IH: blackfly (simulium) bite
Onchocerca volvulus
Habitat
Subcutaneous tissue
Onchocerca volvulus
Disease
Onchocerciasis, river blindness, dermatitis
Mansonella pertans
Infective stage
3rd stage filarial larvae
Mansonella pertans
MOT
Vector bite
Mansonella pertans
Host
DH: Human
IH: Midge (Culicoides)
Mansonella pertans
Habitat
Subcutaneous tissue
Mansonella pertans
Disease
Asymptomatic
o Adult migration: transient subcutaneous swelling, pericarditis, pleuritic, ocular symptoms
Mansonella ozzardi
Infective stage
3rd stage filarial larvae
Mansonella ozzardi
MOT
Vector bite
Mansonella ozzardi
Host
DH: Human, monkey
IH: blackfly (simulium), Midge (Culicoides)
Mansonella ozzardi
Habitat
Peritoneal cavity or pleural cavity, less frequently in pericardium
Mansonella ozzardi
Disease
Asymptomatic
o Fever, pruritis, arthralgia, headache, rashes, lymphadenopathy, edema, and pulmonary symptoms
Mansonella streptocerca
Infective stage
3rd stage filarial larvae
Mansonella streptocerca
MOT
Vector bite
Mansonella streptocerca
Host
DH: Human, chimpanzee
IH: Midge (Culicoides)
Mansonella streptocerca
Habitat
Dermis
Mansonella streptocerca
Disease
Asymptomatic
o Pruritis, dermatitis, hyperpigmented lesion
Dracunculus medinensis
Infective stage
Infective larvae
Dracunculus medinensis
MOT
Drinking unfiltered water containing copepods
Dracunculus medinensis
Host
IH: copepods
Dracunculus medinensis
Habitat
Subcutaneous tissues
Dracunculus medinensis
Disease
Guinea worm disease
Skin infection
Dog hookworm
Dirofilaria immitis
Dirofilaria immitis
Infective stage
Infective larvae
Dirofilaria immitis
MOT
Mosquito bite
Dirofilaria immitis
Host
Some zoonotic
DH: carnivore (dogs, cayote, jackal, wolf)
IH: mosquito (Cutex, Aedes, Anopheles, Mansonia)
Dirofilaria immitis
Habitat
Heart
Dirofilaria immitis
Disease
Pulmonary disease
Coin lesion
Papuple ulcers