Discovery of Microorganisms Flashcards
Early civilizations (e.g., ___) showed signs of using toilets and sewers dating back as far as 2800 BC
Crete, India, Pakistan, and Scotland
___, 315 AD: Public Lavatories with flowing water where people routinely socialized and conducted business.
Rome
___, 384 AD: first discovered spontaneous generation
Aristotle
Aristotle, 384 AD: first discovered ___
spontaneous generation
The Chinese as early as 589 AD produced ___, while Europeans used ___.
toilet paper
moss/hay
According to Aristotle, it was:
“readily observable that ___ arise from the dew which falls on plants, fleas from putrid matter, mice from dirty hay.”
aphids
People attributed diseases to ___ and ___
witchcraft and the devil
Later they believed disease was caused by ___(unpleasant or unhealthy smell)
miasma
1632-1723 ___: was the first to demonstrate the presence of micro-organism via microscope
Antony van Leeuwenhoek
As a draper (merchant who sells cloth and dry goods), he used lenses to examine cloth. This probably led to his interest in lens-making.
He assembled hundreds of microscopes, some of which magnified objects 270 times.
As he looked at things with his microscopes, he discovered “micro” organisms - organisms so tiny that they were invisible to the naked eye.
Antony van Leeuwenhoek
Anton van Leeuwenhoek called these tiny living organisms “___”. He first described bacteria, protozoans, and many cells of the human body.
animalcules
Father of Bacteriology
Antony van Leeuwenhoek
Father of Protozoology
Antony van Leeuwenhoek
Father of Microbiology
Antony van Leeuwenhoek
opposed the prevailing theory of Spontaneous Generation
He was the first person to challenge the theory of spontaneous generation by demonstrating that maggots come from the eggs of flies.
Francesco Redi 1668
Experiments with meat and flies
Francesco Redi 1668
He is referred to as the “founder of experimental biology”
Francesco Redi 1668
___ is the concept that living organisms arise from non-living material.
Spontaneous generation
Believed death following childbirth (puerperal fever is often caused by the material on the hands of midwives or attending physicians.
Oliver Wendell Holmes Sr.
Noticed death rates higher in maternity wards staffed by medical students than in those attended by midwives. Death rates decreased in summer.
Ignaz Semmelweis
he emphasized The importance of handwashing
Ignaz Semmelweis
He discovered that Streptococcus pneumoniae was the first organism shown to have an important extracellular bacterial pathogen
Louis Pasteur (1822-1895)
He also developed vaccines (like the anthrax vaccine) to prevent cholera, anthrax, and swine erysipelas (a skin disease)
Louis Pasteur (1822-1895)
Louis Pasteur also developed vaccines (like the ___ vaccine) to prevent cholera, anthrax, and swine erysipelas (a skin disease)
anthrax
Louis Pasteur discovered that ___ was the first organism shown to have an important extracellular bacterial pathogen
Streptococcus pneumoniae
___ is caused by Bacillus anthracis
Anthrax
Anthrax is caused by ___
Bacillus anthracis
Demonstrated that sterile infusions will stay sterile in specially constructed flasks even when they were left open to the air
Louis Pasteur (1822-1895)
Explained differences in results obtained from different laboratories
Proved Pasteur correct
John Tyndall
He concluded that different infusions require different boiling times to be sterilized
Because of heat-resistant microorganisms: Endospores
John Tyndall
John Tyndall discovered heat-resistant microorganisms called ___
Endospores
What age of microbiology includes:
Rapid advances by Pasteur and Robert Koch
Discovery of agents of many diseases and the role of immunity in the prevention and cure of disease
Discoveries include:
Fermentation and pasteurization
The germ theory of disease
Vaccination
Golden Age of Microbiology
The golden age of microbiology includes the following discoveries:
Rapid advances by Pasteur and Robert Koch
Discovery of agents of many diseases and the role of immunity in the prevention and cure of disease
Discoveries include:
Fermentation and pasteurization
The germ theory of disease
Vaccination