Diffusion, Active Transport, Osmosis 2.1.5 (d,e) Flashcards
what are the two types of exchange of substances between cells?
passive
active
what is active exchange?
exchange which requires metabolic energy
what is diffusion?
the net movement of particles from a region of high concentration to low concnetration
what is simple diffusion?
diffusion in the absence of a barrier/membrane
which molecules can freely pass through the phospholipid bilayer?
non-polar molecules (like oxygen)
small molecules
which molecules cannot pass freely through the phospholipid bilayer?
charged molecules (ions)
polar molecules (water)
large molecules
why can’t charged molecules pass through the phospholipid bilayer?
they are charged and thus repelled by the hydrophobic fatty acid core
can water diffuse through the phospholipid bilayer?
yes but very slowly
as it is polar it is only partially charged
why are membranes partially permeable?
they allow certain molecules in and not others
what affects the rate of diffusion?
temperature
concentration gradient
surface area
thickness of membrane
how does an increased temperature affect the rate of diffusion?
a higher temperature means the particles have more kinetic energy to so move at higher speeds
how does an increased concentration gradient affect the rate of diffusion?
a steeper concentration gradient between two regions will increase the rate of diffusion
how does the thickness of the membrane affect the rate of diffusion?
the thinner the membrane the shorter the diffusion distance so the rate of diffusion increases
how does surface area affect the rate of diffusion?
a larger surface area the faster the rate of diffusion
what is facilitated diffusion?
diffusion across a membrane through the use of a channel and carrier proteins
what two proteins are used in facilitated diffusion?
carrier proteins
channel proteins
how are carrier proteins used in facilitated diffusion?
used to move large molecules (polar molecules and ion) down the concentration gradient
how does a carrier protein work passively?
large molecule binds to the carrier protein
protein changes shape
the molecule is released on the opposite side
how are channel proteins used in facilitated diffusion?
they have hydrophilic interiors which allow large polar molecules to pass through
what factors affect facilitated diffusion?
temperature
concentration gradient
surface area
membrane thickness
number of channel proteins present
how does the number of channel proteins present affect the rate of diffusion?
the more channel proteins the higher the rate of diffusion
what is active transport?
the movement of molecules/ions into a cell from a region of low concentration to high concnetration
is active transport active or passive?
active
require ATP
outline active transport
the molecule binds to receptors in the carrier protein
ATP binds to the carrier protein and is hydrolysed to from ADP + P
the P group binds to the carrier protein to cause it to change it’s shape
this new shape opens up on the other side of the cell, with the molecule being released to enter the cell
ADP + P recombine to form ATP and the carrier protein returns to it’s original shape