Diffuse alveoli damage Flashcards

1
Q

What is it

A

An acute response to injury in the lungs

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2
Q

Aetiology of DAD

A
  • trauma
  • radiation
  • infection
  • drugs
  • chemical
  • autoimmune
  • circulatory shock
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3
Q

Histology

A
Exudate stage- up to 7 days after damage:
-protein rich oedema 
-denuded basement membrane 
-hyaline membranes 
-fibrin 
Proliferative stage
-Fibroblast proliferation 
-epithelium proliferation
-scarring in interstitium/airspaces
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