Differential Diagnosis Flashcards
DDx for adult infratentorial mass
MHAMS
Mets, hemangioblastoma, astrocytoma, medulloblastoma, subependymoma
DDx for adult supratentorial mass
MANOL
Mets, astrocytoma, central neurocytoma, oligodendroglioma, lymphoma
DDx for pediatric supratentorial neoplasms
GPEC
Glioma, PNET, ependymoma, choroid plexux tumors
DDx for pediatric infratentorial neoplasms
AMG ERC
Astrocytoma (pilocytic), medulloblastoma, ependymoma (floor of 4th vent), atypical rhabdoid teratoid tumor, choroid plexus papilloma
DDx for superficial gliomas
DNET, ganglioglioma, pleomorphic xanthoastrocytoma
DDx for adult suprasellar mass
Adenoma, meningioma, aneurysm
DDx for pediatric suprasellar mass
Craniopharyngioma, Rathke’s cleft cyst, glioma, hypothalamic harmatoma, germinoma, LCH
DDx for infundibular mass
MD GELS
Mets, dermoid, germinoma, EG, lymphoma, sarcoma
DDx for infundibular cyst
Rathke cleft cyst
DDx for pineal region mass
GTP
Germinoma, teratoma, pineal parenchymal tumors, pineoblastoma, pineocytoma, vein of Galen aneurysm
DDx for CP angle tumors
SAME
Schwannoma, arachnoid cyst, meningioma, epidermoid
DDx for septum pellucidum region tumors
Central neurocytoma, supependymoma,
DDx for lateral ventricle mass, anterior
Subependymoma, central neurocytoma, subependymal giant cell tumor, ependymoma, astrocytoma
DDx for lateral ventricle mass, posterior
Choroid plexus tumors, meningioma, mets
DDx for third ventricle cyst
Colloid cyst
DDx for fourth ventricle mass
Ependymoma, subependymoma, choroid plexus tumors
DDx for cystic mass with nodule
PGP H
Pilocytic astrocytoma, ganglioglioma, pleomorphic astrocytoma, hemangioblastoma
DDx for ependymal enhancement
CMV, lymphoma
DDx for pediatric parenchymal calcifications
CMV (periventricular), toxoplasmosis (diffuse)
DDx for leptomeningeal enhancement
Bacterial, carcinomatosis, lymphoma
DDx for thick parenchymal enhancement
SICI
Sarcoid, intracranial hypotension, carcinomatosis, infection
DDx for basilar meningitis
TB, fungal
DDx for bilateral basal ganglia abnormality
NH4
NF1, hepatic encephalopathy, hyperalimentation, hyper/hypo/pseudohypothyroidism), hypoxia/anoxia
DDx for hypoxia
Acute, CO, toxins, enzyme deficiencies
DDx for caudate atrophy
Huntington’s
DDx for basal ganglia calfications
HIV, calcium-phosphate metabolism
DDx for abnormal ventricles
Max hydrocephalus, hydranencephaly, holoprosencephaly
DDx for intraparenchymal hemorrhage
AHA MPH
AVM, HTN hemorrhage, amyloid angiopathy, mets, primary neoplasms, herpes
DDx for adult diffuse white matter disease
HB RT
HIV, Binswenger, radiation, toluene
DDx for pediatric diffuse white matter disease
Adrenoleukodystrophy, dysmyelinating disease
DDx for discreet white matter lesions
HIMA LV
HTN, ischemia, MS, ADEM, lyme disease, vasculitides
DDx for PRES
Eclampsia, cyclosporine, HUS
DDx for U fiber T1 hyperintensities
PML
DDx for fetal hydrocephalus
ABCD
Aqueductal stenosis, bleed, Chiari II, Dandy-Walker
DDx for adult hydrocephalus
MBM
Meningitis, bleed, mass
DDx for multiple masses
D MAT
Demyelinating lesions, mets, abscesses, TB
DDx for corpus callosum mass
GBM, lymphoma
DDx for pontine T2 hyperintensities
Central pontine myelinolysis, infarct (check basilar artery)
DDx for posterior fossa cysts
Dandy-Walker, mega cisterna magna, arachnoid cyst
DDx for elongated superior cerebellar peduncles
Vermian agenesis
DDx for restricted diffusion
I EAB
Infarct, epidermoid, abscess, blood when bright on T1, glioma, meningioma, lymphoma
DDx for congenital developmental spinal lesions
NADEL AC
Neurenteric cyst, arachnoid cyst, dermoid/epidermoid, lipoma, AVM, cavernoma
DDx for spinal infection/inflammation/trauma
SAMMAH
Sarcoid, arachnoiditis, meningitis, myelitis, abscess, hematoma
DDx for tumors of the spine
EHA MSN Mets Lymp
Ependymoma, hemangioblastoma, astrocytoma, meningioma, Schwannoma, neurofibroma
DDx for diffuse intramedullary high T2 signal in the spine
Myelitis, glioma
DDx for central owl sign in the spine
Infarct, west nile virus
DDx for extradural processes in the spine
DSL
Disk disease, synovial cyst, lipomatosis
DDx for extradural bone lesions in the spine
COOMAG
Chordoma, osteosarcoma, osteoblastoma, myeloma, aneurysmal bone cyst, giant cell tumor
DDx for multiple cerebellar and cord lesions
Hemangioblastoma (VHL), mets
DDx for leptomeningeal enhancement
Meningitis, mets, lymphoma
DDx for gray matter involvement
Ischemia, viral
DDx for multiple cord masses
Sarcoid, MS, lymphoma, mets, hemangioblastoma
DDx for long tract involement
ALS, GBS, B12 def
DDx for basal ganglia calcifications
Senescent, phosphate and calcium, post-inflammatory, HIV in utero, Fahr disease
DDx for suprasellar cyst
Ependymal, arachnoid, colloid, epidermoid, cysticercosis, cystic craniopharyngioma
DDx for large ventricles
Alobar holoprosencephaly, hydrocephalus, hydranencephaly
DDx for pituitary stalk thickening
LCH, germinoma, infection, lymphoproliferative disorders, sarcoidosis
DDx for cystic mass with enhancing mural nodule
Pilocytic astrocytoma, hemangioblastoma, mets
DDx for central hyperintensity of the cord
Hydromyelia, syringomyelia, syringobulbia
DDx for posterior column disease
B12 def, nitrous oxide abuse
DDx for convexity SAH
Venous thrombosis, dural AVF, amyloid angiopathy, aneurysm
DDx for supratentorial, intra-axial tumors
Primary: glioma (astrocytoma, GBM, oligodendrioglioma, ependymoma, DNET/PNET, lymphoma)
Secondary: intraparenchymal mets
DDx for supratentorial, extra-axial tumors
Primary: meningioma, pituitary adenoma, epidermoid, dermoid, bone tumors
Secondary: leptomengingeal mets
DDx for intratentorial, intra-axial tumors
Primary: astrocytoma, medulloblastoma (PNET), ependymoma, brainstem glioma, hemangioblastoma
Secondary: intraparenchymal mets
DDx for intratentorial, extra-axial tumors
Primary: schwannoma, meningioma, (epi)dermoid, chordoma
Secondary: leptomeningeal mets
DDx for superficial tumor with homogenous enhancement
Meningioma, lymphoma, anaplastic astrocytoma, mes
DDx for a cyst with enhancing mural nodule
Pilocytic astrocytoma, hemangioblasotma, pleomorphic xanthoastrocytoma, ganglioglioma