Diabetes and pregnancy Flashcards
What is gestational diabetes caused by?
Reduced insulin sensitivity
Complications of gestational diabetes
Macrosomia
Laege for dates foetus
Complications of gestational diabetes
Macrosomia
Laege for dates foetus
->birth risk - shoulder dystocia
Long term risk of T2DM after pregnancy for women
Who and when should people be screened for gesttational diabetes?
24-28 weeks gestation
Women with risk factors or prev gestational diabetes
OGTT
Risk factors for gestational diabetes testing?
Prev gestational diabetes
Prev macosomic baby > 4.5 kg
BMI > 30
Ethnic origin - black caribbean, middle eastern and south asian
FH diabetes - 1st degree
Risk factors for gestational diabetes testing?
Prev gestational diabetes
Prev macosomic baby > 4.5 kg
BMI > 30
Ethnic origin - black caribbean, middle eastern and south asian
FH diabetes - 1st degree
Risk factors for gestational diabetes testing?
Prev gestational diabetes
Prev macosomic baby > 4.5 kg
BMI > 30
Ethnic origin - black caribbean, middle eastern and south asian
FH diabetes - 1st degree
Features of gestational diabetes in foetus
Large for dates foetus
Polyhydraminos (increased amniotic fluid)
Glucose on urine dipstick
How to do an OGTT
75g glucose drink in morning after fast
blood sugar monitored before and after 2 hours
Fasting <5.6 mmol/l
At 2 hours<7.8 mmol/l
How to manage gestational diabetes
Joint diabetes and antenatal clinics with input from dietician
Learn how to monitor and track blood sugar levels
How often to monitor gestational diabetes
4 weekly US scams to monitor foetal growth and amniotic fluid volume from 28 to 36 weeks gestation
What is management fro gestational diabetes depending on fasting glucose?
<7mmol/l - trial of diet and exercise for 2 weeks then metformin then insulin
>6 + macrosomia or > 7 - start insulin and metformin
When do you start insulin and metformin straigh taway in gestational diabetes
> 6 + complication
7
What is used to treat gestational diabetes if decline insulin or cannot tolerate metformin?
Glibenclamide - sulfonylurea
NICE targets for blood sugar levels in pregnant women
Fasting: 5.3 mmol/l
1 hour post-meal: 7.8mmol/l
2 hours post-meal: 6.4 mmol/l
Avoiding levels of 4 mmol/l or below