vulvar cancer Flashcards
What type of cancer most commonly are vulval
SCC - 90%
Malignant melonomas
Risk factors for vulvar cancer
Adavanced age - esp >75 years
Immunosupression
HPV infection
lichen sclerosus
What is vulval intraepithelial neoplasia
Premalignant conition effecting quamous epithelium can lead to cnacer
What is High grade squamous intraepithelial lesions ass with
Type of VIN ass with HPV
Which women does high grade squamous intraepithelial lesion occur in
Younger women aged 35-50 years
What type of VIN is ass with older women - 50-60
Differentiated VIN
What VIN is ass with lichen sclerosis
Differentiated VIN
How diagnose VIN
BIOPSY
How treat VIN
Watch and wait close followup
Wide local excision (surgery) to remove lesion
imiquimod cream
Laser ablation
Presentation vulvar cancer
May be incidental finding in older women eg catheterisation
Vulval lump
Ulceration
Bleeding
Pain
Itching
Lymphadenopathy in groin
What is the appearance of the labia majora in vulvar cancer
Irregular mass
Fungating lesion
Ulceration
Bleeding
Diagnosis and staging of vulvar cancer
Biopsy of lesion
Sentinel node biopsy demonstrate lymph node spread
CT abdomen and pelvis for staging
Staging for vulval cancer
FIGO
Management of vulval cancer
Depends on the staging
Wide local excision to remove cancer
Groin lymph node dissection
Chemotherapy
Radiotherapy
