Chronic conditions and pregnancy Flashcards
What can un or undertreated hyppthyroidism in pregnancy lead to?
Miscarriage
Anaemia
SGA
Pre-eclampsia
Treatment for hypothyroidism
Levothyroxine
Treatment for hypothyroidism
Levothyroxine
What levothryoxine dose need adjusting in pregnancy
25-50mcg increase in dose to accomodate for foetus
Treatment based on TSH level aiming for low to normal
What HPTNsive meds should be stopped in pregnancy?
ACE inhibitors
ARB
Thiazide + thiazide like diuretics
What hypertensive meds are not harmful in pregnancy?
Labetalol - beta blocker
Calcium channel blockers
Alpha blockers
What should women with epilepsy take who are trying to conceive and why?
Folic acid 5mg a day to prevent neural tube defects
Why may pregnancy worsen seizure control?
++ stress
Lack of sleep
Hormonal chnages and altered med regimes
Only present a physical risk in pregnancy
What epileptic meds can be used in pregnancy
Levetiracetam
Lamotrigine
Carbamazepine
Why is sodium valproate avoided in pregnnacy
neural tube defects
Developmental delay
Why is sodium valproate avoided in pregnnacy
neural tube defects
Developmental delay
Why is phenytoin avoided in pregnancy?
Causes Cleft lip and palate
How should RA be controlled before pregnancy?
Well controlled for 3 months before conception
What Rheumatoid drugs are safe in pregnancy
Hydroxochloroquine - first line
Sulfasalazine
Corticosteroids - flare ups
What problems can methotrexate cause in pregnancy?
Teratogenic, causing miscarriage and congenital abnormalities
