Development of the Cardiovascular System Flashcards
*CVS consists of the ____ function early when simple diffusion of nutrients can no longer supply the metabolic needs of the developing embryo
heart, blood vessels and blood cells
*Heart begins to beat on the ____ of incubation in chicken and on the ____ of gestation in man
2nd day
23rd day
*the mechanism involves the ____ and a later ____ which both mean the process of ____
early vasculogenesis
angiogenesis
blood vessel formation
The blood islands in the yolk sac consist of two types of primordial cells: ____ are hematopoietic that gives rise to blood cell lines & ____ (the angioblasts; angeion=vessel) give rise to the endothelial cells of the blood vessels
inner most cells
Outer cells
*Heart tube
At about 3rd week of gestation ____ from the ____ appear to form plexus of vessels lying deep to the horse-shaped prospective ____
angioblastic blood islands
splanchnic mesoderm
pericardial cavity
*Heart tube
These small vessels develop into paired ____
endocardial heart tubes
*Heart tube
Splanchnic mesoderm proliferates and develops into ____ which give rise to the
myocardium and the epicardium
epimyocardial mantle
*Heart tube
Bilateral endocardial heart tubes continue to develop and connect with a pair of vessels, the ____, located on either side of the midline
dorsal aortae
*Heart wall
____ and ____ growth of the embryo shift the endocardial tube medially, ventrally, caudally and fuse in the midline as single endocardial tube beneath the ____
Lateral and cephalic
foregut
*Heart wall
Endocardial tube is surrounded by ____
rich in hyaluronic acid that facilitates cell
movement on the subsequent remodeling of the endocardium
cardiac jelly
*Heart wall
The resulting heart tube is suspended in the pericardial cavity by ____ dorsally and _____ ventrally
dorsal mesocardium
ventral mesocardium
When the heart tube is formed, the embryo is in the ____; about 3mm in length; has 4-12 somites and neural tube is also forming, the heart begins to beat
4th week of gestation
*Subdivisions of the Embryonic Tube
As the heart tube fuses, several ____
appear. From the cephalic to posterior end, the bulges are: truncus arteriosus, conus arteriosus (bulbus cordis), primitive ventricle, atrium and sinus venosus
bulges and sulci
*Subdivisions of the Embryonic Tube
The veins connect to the heart tube via the ____ while the paired dorsal aortae arise
from the aortic arch which in turn arise from the aortic sac=the most cephalic end of the bulbus cordis
sinus venosus
*Subdivisions of the Embryonic Tube
The sulci present are the _____ between
the bulbo cordis and the ventricle, atrioventricular sulcus between the atrium and the ventricle
bulboventricular sulcus
*Subdivisions of the Embryonic Tube
With the convolution the _____ degenerates
dorsal mesocardium