Development Flashcards

1
Q

the formation of primary germ layers begins at ______.

A

8 weeks

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2
Q

ectoderm derives into (4)

A
  • epidermis
  • lens and cornea
  • nervous system
  • internal ear
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3
Q

mesoderm derives into (4)

A
  • skeleton
  • muscle
  • lymphoid tissues
  • kidney and ureters
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4
Q

endoderm derives into (3)

A
  • gut
  • respiratory epithelium and glands
  • bladder
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5
Q

placenta

A
  • 3cm thick disc

- surface facing fetus is smooth and connected to umbilical cord

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6
Q

placenta is important because it ensures_____

A

the fetal and mothers blood do not mix

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7
Q

what increases as the placenta villi grow

A

conductivity

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8
Q

placentation

A
  • starts around day 11

- include both the mother and embryonic tissue

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9
Q

syncytiotrophoblast… (during placentation) and the mesenchyme….

A

grows into chorionic villi; form blood vessels from the embryoblast

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10
Q

chorionic vill… (during placentation)

A

digest lacunae spaces that fill with maternal blood

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11
Q

what forms the placenta (2)

A

stratum deciduas with the chorionic villi

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12
Q

ectopic pregnancy (2)

A
  • blastocyst implants outside the uterus

- most of the time in the uterine tube that ruptures after 12 weeks

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13
Q

capacitation

A

sperm must remove a layer of cholesterol and inhibitory factors from the acrosomal vesicle that require the females secretions

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14
Q

following capacitation the sperm are

A

fragile, will last only 48 hours post ejaculation

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15
Q

what is the window of opportunity for pregnancy (2)

A

48 hours before ovulation

12-24 hours after

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16
Q

what is the last step of sperm for fertilization

A

capacitation

17
Q

the first sperms to arrive must? how is this accomplished

A

breakdown the corona radiata; release of hyaloronidases following the acrosomal reaction

18
Q

the second wave of sperm….

A

attach to receptors on the zona pellucida and also trigger acrosomal reaction

19
Q

the first sperm to penetrate the zona pellucida….

A

will fuse with the plasma membrane of the egg and release its pronuclei

20
Q

polyspermy

A

more than 1 sperm entering an egg

21
Q

what are the mechanisms to prevent polyspermy?

A

fast block

slow block

22
Q

fast block (3)

A
  • penetration depolarizes the egg and causes opening of voltage sensitive sodium channels
  • occurs throughout the egg
  • inactivates sperm receptors on the egg
23
Q

slow block (3)

A
  • depolarization of the fast block causes calcium sensitive channels to open
  • calcium causes release of cortical granules that are spread between the egg and zona pellucida
  • fluid begins to fill the area between the zona and egg
24
Q

zygote

A

fertilized egg

25
Q

cleavage (2)

A
  • rapid mitosis without growth

- occurs 30 hours post fertilization

26
Q

hatching (3)

A
  • cell mass no longer undergoing cleavage
  • time egg feeds on uterine milk
  • blastocyst begins to form
27
Q

blastocyst

A

a hollow sphere with an outer layer and inner layer

28
Q

inner layer of blastocyst

A

embryoblast (becomes embryo)

29
Q

outer layer of blastocyst

A

trophoblast (becomes chorion)

30
Q

chorion

A

fetal part of the placenta

31
Q

dizygotic twins (2)

A
  • fraternal twins

- 2 eggs ovulated and fertilized

32
Q

monozygotic twins (2)

A
  • splitting of the embryoblast

- maternal twins

33
Q

syncytiotrophoblast (3)

A
  • fusion of the trophoblast
  • secretes HCG
  • becomes chorion