Development Flashcards

1
Q

the formation of primary germ layers begins at ______.

A

8 weeks

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2
Q

ectoderm derives into (4)

A
  • epidermis
  • lens and cornea
  • nervous system
  • internal ear
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3
Q

mesoderm derives into (4)

A
  • skeleton
  • muscle
  • lymphoid tissues
  • kidney and ureters
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4
Q

endoderm derives into (3)

A
  • gut
  • respiratory epithelium and glands
  • bladder
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5
Q

placenta

A
  • 3cm thick disc

- surface facing fetus is smooth and connected to umbilical cord

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6
Q

placenta is important because it ensures_____

A

the fetal and mothers blood do not mix

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7
Q

what increases as the placenta villi grow

A

conductivity

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8
Q

placentation

A
  • starts around day 11

- include both the mother and embryonic tissue

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9
Q

syncytiotrophoblast… (during placentation) and the mesenchyme….

A

grows into chorionic villi; form blood vessels from the embryoblast

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10
Q

chorionic vill… (during placentation)

A

digest lacunae spaces that fill with maternal blood

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11
Q

what forms the placenta (2)

A

stratum deciduas with the chorionic villi

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12
Q

ectopic pregnancy (2)

A
  • blastocyst implants outside the uterus

- most of the time in the uterine tube that ruptures after 12 weeks

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13
Q

capacitation

A

sperm must remove a layer of cholesterol and inhibitory factors from the acrosomal vesicle that require the females secretions

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14
Q

following capacitation the sperm are

A

fragile, will last only 48 hours post ejaculation

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15
Q

what is the window of opportunity for pregnancy (2)

A

48 hours before ovulation

12-24 hours after

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16
Q

what is the last step of sperm for fertilization

A

capacitation

17
Q

the first sperms to arrive must? how is this accomplished

A

breakdown the corona radiata; release of hyaloronidases following the acrosomal reaction

18
Q

the second wave of sperm….

A

attach to receptors on the zona pellucida and also trigger acrosomal reaction

19
Q

the first sperm to penetrate the zona pellucida….

A

will fuse with the plasma membrane of the egg and release its pronuclei

20
Q

polyspermy

A

more than 1 sperm entering an egg

21
Q

what are the mechanisms to prevent polyspermy?

A

fast block

slow block

22
Q

fast block (3)

A
  • penetration depolarizes the egg and causes opening of voltage sensitive sodium channels
  • occurs throughout the egg
  • inactivates sperm receptors on the egg
23
Q

slow block (3)

A
  • depolarization of the fast block causes calcium sensitive channels to open
  • calcium causes release of cortical granules that are spread between the egg and zona pellucida
  • fluid begins to fill the area between the zona and egg
24
Q

zygote

A

fertilized egg

25
cleavage (2)
- rapid mitosis without growth | - occurs 30 hours post fertilization
26
hatching (3)
- cell mass no longer undergoing cleavage - time egg feeds on uterine milk - blastocyst begins to form
27
blastocyst
a hollow sphere with an outer layer and inner layer
28
inner layer of blastocyst
embryoblast (becomes embryo)
29
outer layer of blastocyst
trophoblast (becomes chorion)
30
chorion
fetal part of the placenta
31
dizygotic twins (2)
- fraternal twins | - 2 eggs ovulated and fertilized
32
monozygotic twins (2)
- splitting of the embryoblast | - maternal twins
33
syncytiotrophoblast (3)
- fusion of the trophoblast - secretes HCG - becomes chorion