Dermatopathology

Question 1

vitiligo

Answer 1

macules/patches of skin with loss of pigment

Question 2

what ares does vitiligo most commonly affect

Answer 2

• hands
• wrists
• perioral regions
• anogenital regions

Question 3

is vitiligo an autoimmune disease

Answer 3

often in Hashimoto’s, DM1, and Addison’s Dz

Question 4

Freckles

Answer 4

hyperpigmented lesion

Question 5

Do freckles darken in sunlight

Answer 5

YES

Question 6

Lentigo

Answer 6

Hyperpigmented lesions due to increased number of melanocytes along the basement membrane

Question 7

Does lentigo darken in the sunlight

Answer 7

NO

Question 8

microscopic findings of acute inflammatory skin disorders

Answer 8

• neutrophiles
• edema
• epidermal, vascular, or SQ injury

Question 9

examples of acute inflammatory conditions

Answer 9

• urticaria
• acute eczematous dermatitis
• erythema multiforme

Question 10

pathophysiology of urticaria

Answer 10

local accumulation and degranulation of mast cells with histamine release and edema

Question 11

urticaria - skin findings?

Answer 11

• pruritic nodule
• edematous swelling (wheals)
• formation of bullae

Question 12

Urticaria - microscopic findings?

Answer 12

perivascular edema

Question 13

morbilliform rash

Answer 13

“measles-like”

can be due to:

• measles
• drug reaction (Abx- sulfa, PCN)

Question 14

Exanthem

Answer 14

rash outside on skin

Question 15

Enanthem

Answer 15

rash internally (mucous membranes)

Question 16

Hand-foot-mouth disease – exanthem or enanthem?

Answer 16

BOTH

Question 17

acute eczematous dermatitis

Answer 17

erythema, edema, and vesicle formation