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Gastroenterology > Dermatology > Flashcards

Dermatology Flashcards

1
Q

Acne Vulgaris in pregnancy :

A

Oral Erythromycin

Erythro-MOM-mycin—mom—safe in pregnancy

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2
Q

Potency of steroids :

A

Colombo Children—Cmb Ch

Clobetasol—Soul-Potent.
M
B—Betamethasone

C—Colbetasone
H—Hydrocortisone

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3
Q

K/c/o Atopic eczema—on Hydrocortisone. Which drug to give next ?

A

Give colbebetasone.

Colombo Children—Cmb Ch

Clobetasol—Soul-Potent.
M
B—Betamethasone

C—Colbetasone
H—Hydrocortisone

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4
Q

Blistering itchy rash around umbilicus + 2/3rd trimester.

A

Pemphigoid gestations

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5
Q

Prurtic lesion around Abdominal Striae + last trimester. Dx?

A

Polymorphic Eruption of Pregnancy

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6
Q

Most important prognostic factor for Melanoma :

A

Invasion Depth of the tumour

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7
Q

Eczema Herpeticum, which viruses are involved ?

A

HSV 1
HSV 2
Coxsackie Virus

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8
Q

Apart from HSV1 and HSV 2 , which virus is involved in eczema herpeticum ?

A

Coxsackie virus

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9
Q

Which other dermat condition is ass with eczema herpeticum ?

A

Atopic Dermatitis

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10
Q

K/C/O Atopic eczema + erythematous vesicles with some lesions eroded + Face—extensor surface—palms and soles—oral ulcers. Dx?

A

Eczema Herpeticum

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11
Q

Purple non blanching + Reticular rash—net like pattern across limbs and torso

A

Livedo reticularis

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12
Q

Livedo reticularis is ass with which Rheumat condition ?

A

SLE

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13
Q

Most specific antibody in SLE :

A

Anti Smith antibodies

SMecific antibody—Anti SMith

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14
Q

Gold standard diagnostic test for Dermatitis herpitformis :

A

Skin Biopsy—To look for deposition of IgA in Dermis.

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15
Q

Which dermatology condition is ass with coeliacs ?

A

Dermatitis herpetiformis

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16
Q

Which Ig in Dermatitis Herpetiformis ?

A

IgA

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17
Q

on which surface is dermatitis herpetiformis ?

A

On extensor surface.

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18
Q

K/C/O coeliacs + Itensly itchy vesicular skin lesion + extensor surfaces—elbows, buttocks , knees. Dx?

A

Dermatitis Herpetiformis

Ix—Skin Biopsy to look for deposition of IgA in dermis

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19
Q

Melanoma + Red or Black lump on face which bleeds. Dx ?

A

Nodular Melanoma

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20
Q

Most aggressive and early metastasis form of Melanoma.

A

Nodular Melanoma

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21
Q

Light brown thickened patch of skins in axillae and palms + Small finger like projections from lips + pruritis + extensive lesion involving palms and soles and mucosa.
Underlying diagnosis and Ix ?

A

Acanthosis Nigricans secondary-to Gastric Cancer.

Ix—Gastroduodenoscopy.

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22
Q

Lesion on lower lip. Dx and Rx for minimal scarring.

A

Squamous Cell Carcinoma.

Rx for minimal scarring: MOHS Micrographic Surgery.

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23
Q

Shiny erythematous plaque with silvery surface on flexure aspect—Armpits, groins, calves + Auspitz sign positive. Dx and Rx:

A

Flexural Psoriasis

Rx— First line —Topical Steroids—

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24
Q

First line Rx in Flexural Psoriasis :

A

Topical Steroids

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25
Q

Trichophyton Rubrum nail infection Rx:

A

Oral Terbinafine for 12 weeks

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26
Q

is hypertension a side effect of retinoids ?

A

No

Intracranial Hypertension is a side effect of retinoids

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27
Q

seborrhoeic dermatitis Common association :

A

HIV
Parkinson’s

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28
Q

Nivolumab associated colitis Rx :

A

Oral prednisolone

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29
Q

Pityriasis Versicolor is ass with which HHV ?

A

Ass with HHV 8 ( Herpes Hominis Virus )

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30
Q

HHV 7(Herpes Hominis ) is associated with :

A

Pitryriasis roseaola

7 Homies proposed with a ROSE to Namita.

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31
Q

Pitryriasis Roseola is associated with which Herpes ?

A

HHV 7.

7 Homies proposed with a ROSE to Namita.

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32
Q

HHV 7 is :

A

Herpes Hominis

7 Homies proposed with a ROSE to Namita.

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33
Q

H/o URTI —-Herald Patch on Trunk—Erythematous oval scaly patches

A

Pitryriasis Roseola

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34
Q

Pitryriasis Roseola

A

H/o URTI —-Herald Patch on Trunk—Erythematous oval scaly patches

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35
Q

K/C/O Lung cancer + small erythematous annular patch, slowly enlarging into polycyclic patches with a wood-grain appearance

A

Erythema Gyratum Repens

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36
Q

Nivolumab + Scaly Red Plaque on extensor surface. Dx?

A

Topical Betamethasone

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37
Q

Alopecia Areata Rx

A

Topical Steroids

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38
Q

Keratocanthoma Rx?

A

Urgent Referral to Dermatology for Urgent Excision.

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39
Q

Volcano like spot on left cheek :

A

Keratocanthoma

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40
Q

Keloid scars - more common in

A

Young black males

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41
Q

Psoriasis on extensors first line

Psoriasis on flexure aspect :

A

Topical steroids plus vitamin D analogue

Topical steroids

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42
Q

Not a recognised cause of Eryhroderma :

A

Lichen Planus

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43
Q

Lupus Pernio is ass with ?

A

Sarcoidosis

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44
Q

TB ass skin conditions :

A

Lupus Vulgaris
Scrofuloderma
verrucosa Cutis

Erythema Nodosum

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45
Q

Painful Multiple circular ulcerated lesions between 1 and 3mm in diameter on the right side of her face, spreading from the ear to the chin and neck. Her hearing is unaffected.

A

Eczema Herpeticum

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46
Q

Mucosal Involvement in Steven Johnson Syndrome ?

A

Prominent

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47
Q

Nikolsky sign in Steven Johnson ?

A

Positive.

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48
Q

K/C/O HIV—Fever Myalgia—Flaccid Blistering and Rash in Torso and Oral Mucosa + Nikolsky-Positive

A

Steve Johnson Syndrome

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49
Q

Non Healing Painless Ulcer ass with a chronic scar on leg. Dx?

A

Squamous Cell Carcinoma

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50
Q

Common Complication of seborrhoeic dermatitis:

A

Otitis External and Blepharitis

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51
Q

Skin cancer associated with Transplant :

A

Squamous Cell Carcinoma

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52
Q

Numerous scaly patches are noted on the forehead, as well as greasy, flaky lesions in the nasolabial folds.Dx and Complication

A

Seborrhoeic dermatitis

Complication- Blepharitis

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53
Q

itchy white spots typically seen on the vulva of elderly women

A

Lichen Sclerosus

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54
Q

porphyria cutanea tarda ass with ?

A

Hepatitis C

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55
Q

K/C/O Hepatitis C + onycholysis and a blistering erythematous rash on the dorsal aspect of the hand and face + hyperpigmentation and hypertrichosis on the face

A

Porphyria Cutanea Tarda.

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56
Q

Which chronic condition is ass the most with seborrhoeic dermatitis

A

HIV

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57
Q

Rx for Pyoderma Gangrnosum:

A

Oral prednisolone

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58
Q

On Leg—initially Small Pustule/Red Bump—Skin breaks down—Resulting in painful ulcers with purple violaceous edges. Dx:

A

Pyoderma Gangrenosum

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59
Q

Pyoderma Gangrenosum

A

On Leg—initially Small Pustule/Red Bump—Skin breaks down—Resulting in painful ulcers with purple violaceous edges

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60
Q

Pyoderma Gangrenosum ass features :

A

IBD
RA
SLE
Leukemias

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61
Q

Most common side effect of Isoretinoids :

A

Dry skin

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62
Q

Lichen planus occurs in which aspect ?

A

Flexure aspect

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63
Q

Lichen Planus oral mucosa involvement ?

A

Oral Mucosal involvement present

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64
Q

white lacy pattern in oral mucosa :

A

Oral Lichen Planus

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65
Q

Most common site for keloid scar :

A

Sternum

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66
Q

Scabies Rx:

A

all skin including scalp + leave for 12 hours + retreat in 7 days

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67
Q

Hyperhydrosis first line :

A

Topical Alluminium Chloride

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68
Q

Tonsillitis + Acute onset of tear-drop scaly papules / Lesion less than 1 cm + on trunk and limbs. Dx:

A

Guttate psoriasis

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69
Q

Holiday + She also notes that the skin on her hands is extremely fragile and tears easily + Hypertrichosis

A

Porphyria Cutanea Tarda

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70
Q

Mucosal lesions + Blistering Flaccid lesion.

A

Pemphigus Vulgaris

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71
Q

Mucosal lesion in Bullous Pemphigoid ?

A

No

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72
Q

Mucosal lesion Pemphigus Vulgaris ?

A

Yes

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73
Q

Bullae in Bullous Pemphigoid ?

A

Tense Bullae or Tense Blisters

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74
Q

Bullae in Pemphigus Vulgaris ?

A

Flaccid

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75
Q

Pellagara is due to deficiency of :

A

B3 ( Pellagara )

76
Q

Rosacea first line :

A

Topical Ivermectin

77
Q

Rosacea becomes worse with :

A

Sunlight and Alcohol

78
Q

Rosacea severe papules Rx:

A

Topical Ivermectin and Oral Doxycycline

79
Q

3rd trimester + Pruritis on lower abdomen and striae

A

Polymorphic eruption of pregnancy

80
Q

Polymorphic eruption of pregnancy Site :

A

Abdomen Striae and Lower Abdomen

81
Q

Pompholyx eczema Is aggravated by :

A

Humidity
High Temperature

82
Q

Intense pruritic erythematous/burning on palmar aspect of hands and soles. Dx?

A

Pompholyx eczema

83
Q

Pompholyx eczema

A

Intense pruritic erythematous/burning on palmar aspect of hands and soles

84
Q

H/o Exposure to sunlight + Asymotomatic Tan Brown lesion on temple region on face + since 5 years:

A

Lentigo Maligna

85
Q

Total Parentral Nutrition can lead to which Mineral deficiency ?

A

Zinc deficiency

86
Q

TPN/ Alcohol excess + rash around mouth

A

Zinc deficiency

87
Q

Most common form of malignancy ass wth Acanthosis Nigricans is :

A

Gastric adenocarcinoma

88
Q

Histology of squamous cell carcinoma :

A

Keratin Pearls

89
Q

Rash of Eczema Herpeticum

A

monomorphic punched-out erosions and blisters

90
Q

Eczema Herpeticum ass with :

91
Q

Eczema Herpeticum Rx:

A

IV Acyclovir

92
Q

Most common cancer in lower lip ?

A

Squamous cell carcinoma

93
Q

Which cells are involved in Steven Johnson Syndrome :

A

T Cells

Delayed Hypersensitivity Reactoin—Sensor door is buffering(delayed), therefore Tomahawk axe is used to break the door

94
Q

Minocycline side effect:

A

Irreversible sin pigmentation

95
Q

Role of emolients in Seborrhoeic Dermatitis :

96
Q

Which drug not to give in Rosacea ?

97
Q

Actinic Keratosis Rx:

A

Topical Flouroracil

98
Q

Elderly + Sun exposure + Red scaly lesion, which now is erythematous and rough to touch + On Sun exposed area—Back of arm + Face + Scalp

A

Actinic Keratosis

99
Q

two month history of a rapidly growing lesion on his right forearm. The lesion initially appeared as a red papule but in the last two weeks has become a crater filled centrally with yellow/brown materia

A

Keratocanthoma

100
Q

Tiinea Capitis is caused by :

A

Trichophyton tonsurans

101
Q

Non Sedating anti histamines :

A

Loratidine

102
Q

Pemphigoid Vulgaris immunofluorescence of the skin biopsy:

A

IgG and C3 at dermo epidermal junction

P3mphiGoid—IgG and C3

103
Q

Is Alopecia a feature of Zinc deficiency ?

104
Q

Is short stature a feature of Zinc Deficiency ?

105
Q

Is Gingivitis a feature of zinc deficiency ?

106
Q

Most associated with onycholysis ?

107
Q

Does phenytoin cause alopecia ?

A

No

It causes Hirsutism

108
Q

Ciclosporin side effect ?

A

Hypertrichosis

109
Q

Psoriatic Arthritis Rx:

A

Etanercept

110
Q

Alcohol + rash around the anus + loss of libido and Impotence. Dx:

A

Zinc Deficiency

111
Q

Lichen planus first line :

A

Topical Potent steroids

112
Q

H/o holiday + on trunk—patches may be hypopigmented, pink or brown (hence versicolor) + pruritis

A

Dx: Pityriasis Versicolor
Malasazia Furfur

Rx: Ketoconazole shampoo

113
Q

systemic mastocytosis Ix?

A

Urinary Histamine

114
Q

H/o Depression, Anxiety—linear well demarcated skin lesions which appear excoriated + La Belle Indifference —Apathy and Indifference towards lesion.

A

Dermatitis Artefacta.

115
Q

Dermatitis Artefacta.

A

H/o Depression, Anxiety—linear well demarcated skin lesions which appear excoriated + La Belle Indifference —Apathy and Indifference towards lesion.

116
Q

Which meds exacerbate Plaque Psoriasis ?

A

B blockers—Propranolol

117
Q

Malnourished child + acral, periorificial and perianal distribution + Poor cognitive and Growth development

A

Zinc Deficiency

118
Q

Abdominal pain+ Diarrhoea+ Repeated episodes of flushing + urticarial skin lesions on the trunk.

A

Systemic Mastocytosis

119
Q

Systemic Mastocytosis

A

Abdominal pain+ Diarrhoea+ Repeated episodes of flushing + urticarial skin lesions on the trunk.

120
Q

Pyoderma Gangrnosum First line Rx:

A

Oral Prednisolone

121
Q

Tense Blistering lesion on legs+ No mucosal Involvement

A

Bullous Pemphigoid

122
Q

Which psych meds can trigger Psoriasis ?

123
Q

Diabetes + waxy yellow shin lesions

A

necrobiosis lipoidica diabeticorum

124
Q

treatment of choice for facial hirsutism

A

Topical Elfornithine

125
Q

Hyperthyroidism/Graves disease skin manifestation :

A

Pretibial myxoedema: B/L symmetrical Non Pitting oedema—Orange peel appearance

126
Q

Pretibial myxoedema:

A

Associated with Hyperthyroidism/graves + B/L symmetrical Non Pitting oedema—Orange peel appearance

127
Q

Pellagara Triad and cause :

A

cause: B3(Niacin). Triad : dermatitis, diarrhoea and dementia

128
Q

patch of pigmented skin on her toe, which has been slowly enlarging over the past five months+ proximal nail fold affected. Dx?

A

Acral lentiginous melanoma

129
Q

HIV + extensive pink umbilicated lesions visible on his trunk

A

Molloscum Contagiosum

130
Q

In adults molloscum contagiousum is associated with :

131
Q

Is Lupus Vulgaris is associated with Koebner’s ?

132
Q

Is molloscum Conatagiousum associated with Koebner’s ?

133
Q

15 year old—scarring acne. Rx?

134
Q

Patients with scabies who complain of pruritus __ weeks following treatment should be retreated

135
Q

Scabies which type of reaction ?

A

delayed type IV hypersensitivity reaction

136
Q

Is Malathion used in scabies ?

137
Q

Bullous Pemphigoid Rx?

A

Oral Steroids

138
Q

On Groin and Axillae + well-defined pink/brown patches with fine scaling and superficial fissures.

A

Erythrasma

139
Q

Impetigo First line Rx?

A

Topical Fusidic acid

140
Q

Impetigo + Prolonged Hospital Stay + No response to Fusidic acid. Dx and Rx?

A

Suspect MRSA

Rx: Topical Mupirocin

141
Q

necrolytic migratory erythema Which tumour ?

A

All Migratory things are pancreatic tumours

This one : Glucagonoma
Body is necrosed because of glucose

142
Q

most likely antibodies directed against in Bullous Pemphigoid :

A

Hemisdesmosomal BP antigens

143
Q

Apart from legs, where else Pyoderma gangrenosum Can happen ?

A

Stoma site

144
Q

Hard skin on scalp + white, hyperkeratotic lesion on the crown of his head.
No fungal infection on tests.

A

Scalp psoriasis

seb derm: dandruff / hairline scaling & erythema. Also will not generally form discrete area - more diffuse.
kerion: zoonotic fungal infection so often more signs of inflammation than typical human fungal infections

145
Q

Erythema multiforme in which sexual infection ?

A

Herpes simplex virus

146
Q

Which antibiotic is associated with Steven Johnson syndrome ?

A

Sulphonamides—Co trimoxazole

147
Q

Is Azoospermia associated with Yellow Nail Syndrome ?

148
Q

Yellow Nail Syndrome Associations :

A

Pleural Effusions
Brochiectasis
Chronic Sinus infection
Congenital Lymphoedema

149
Q

K/C/O Hypothryoidism + erythematous rash with patches of hyperpigmentation and telangiectasia is found

A

Erythema Ab Igne

150
Q

DM related skin conditions:

A

Necrobiosis lipoidica
Granuloma annualare
Infection—caddiasis, staph
Neuropathic ulcers
Vitiligo
Lipoatrophy

151
Q

Is Sweet’s syndrome associated with with Diabetes ?

152
Q

Guttate Psoriasis Rx and Rx to accelarate recovery ?

A

Rx: Resolves Sponataneously

To accelarate: Ultraviolet B Phototherapy

153
Q

Porphyria Cutana Tarda which enzyme deficiency ?

A

uroporphyrinogen decarboxylase

154
Q

erythematous yellow scaly rash over his nasolabial fold, upper back and chest.

A

seborrhoeic dermatitis

155
Q

Does Roacea have itchiness ?

156
Q

Does seborhoeic dermatitis have itchiness ?

157
Q

Differentiating feature between seborhoeic and Rosacae ?

A

Seborhoeic has itchiness

158
Q

Differentiate carcinoid syndrome from systemic mastocytosis :

A

Carcinoid syndrome may cause abdominal pain, flushing and diarrhoea. However, a reddish-brown papular rash which is Darier’s sign positive is much more characteristic of systemic mastocytosis than carcinoid syndrome.

159
Q

Seborrhoeic dermatitis - first-line treatment:

A

Topical Ketoconazole

160
Q

Pityriasis is caused by :

A

Malasazia Furfur

161
Q

Pregnancy + large, flat, symmetrical, brown-pigmented patch across her cheeks, forehead, nose and upper lip.

162
Q

Diagnosis for allergic contact dermatitis :

A

Skin Patch test

163
Q

Which epileptic drugs causes Erythema Multiforme ?

A

carbamazepine

164
Q

Which two condition most associated with Acanthosis Nigricans ?

A

Gastric Cancer
Hypothyroidism

165
Q

Psoralen and PUVA therapy can lead to :

A

Squamous Cell Carcinoma

166
Q

Difference between allergic contact dermatitis and Irritant Contact Dermatitis :

A

Irritant contact dermatitis : it usually presents with erythema and scaling rather than vesicles

167
Q

Dye + Vesicular rash

A

Allergic contact dermatitis

168
Q

discrete area of hair loss on the left temporal region with no obvious abnormality of the underlying scalp. What is the most likely diagnosis?

A

Alopecia Areata

169
Q

Erythema ab igne can lead to :

A

Squamous Cell Carcinoma

170
Q

Keloid Scar Rx:

A

Intralesional Triamcinolone

171
Q

Known Thyroid Disorder + Number of patches of ‘pale skin’

172
Q

flesh-coloured or pink lesions with a pearly appearance On Nose :

A

Basal Cell Carcinoma—Above Upper lips , so Basal Cell Carcinoma

173
Q

Tender Shin Lesions

A

Erythema Nodosum—common cause—. Sarcoidosis

174
Q

oval, erythematous lesions with a collarette of scale just inside the edge—5-10 cm in size + on trunks

A

Pityriasis Rosacae

Guttate is 1-10 mm in size

175
Q

Hereditary haemorrhagic telangiectasia Inheritance :

A

Autosomal Dominant with age related penetrance

176
Q

Toxic Epidermal Necrolysis is caused by which drug ?

177
Q

Phenytoin + systemically unwell + Positive Nikolsky sign

A

Toxic Epidermal Necrolysis

178
Q

3-year-old girl is taken to her doctor due to a rash on the right upper arm. On examination multiple raised lesions of about 2 mm in diameter are seen. On close inspection a central dimple is present in the majority of lesions. What is the likely diagnosis?

A

Molloscum Contagiosum

179
Q

Management of venous ulceration

A

Compression Bandaging

180
Q

A large, shallow ulcer is visible, superior to the medial malleolus; it does not look infected + High ABPI

A

Venous ulcer

181
Q

Erythema Nodosum confirmed. Next Ix?

A

Chest X ray—to look for the cause such as sarcoidosis and TB

182
Q

Erythema Nodosum healing ?

A

Heals without scarring within 1-2 months

183
Q

Does Amyloidosis cause Erythema Nodosum ?

184
Q

Recurrent epistaxis + Melena + Telangiectasia on face. Dx?

A

Hereditary haemorrhagic telangiectasia

185
Q

Suspected venous ulcer, next investigation ?

186
Q

Diabetes + number of 3-4 mm smooth, firm, papules which are hyperpigmented and centrally depressed.

A

Granuloma annulare

Necrobiosis lipoidica diabeticorum typically presents as well-defined, yellow-brown plaques with atrophic centres and telangiectasia. The size of the lesions tends to be larger than those described in this case.

Gastroenterology (13 decks)

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