Dental and Pharyngitis Pharm Flashcards

1
Q

What causes dental plaque

A

bacterial biofilm

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2
Q

Define gingivitis

A

inflammation of the gums with redness, swelling, and provoked bleeding

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3
Q

Define periodontitis

A

Gingival inflammation accompanied by loss of supportive connective tissue including the periodontal ligament and alveolar bone

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4
Q

What prescription is helpful for gingivitis treatment?

A

Chlorhexidine Gluconate

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5
Q

What and how does chlorhexidine gluconate work

A

basically all bacteria + yeast; bacteriostatic at low doses and bacteriocidal at higher doses

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6
Q

What are the indications for chlorhexidine gluconate?

A

Gingivitis and periodontitis

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7
Q

What is chlorhexidine gluconate used to treat gingivitis?

A

oral rinse swish for 30 seconds with 15 mL; repeat twice daily

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8
Q

How is chlorhexidine gluconate used for periodontitis treatment?

A

periodontal chip - 1 chip inserted into a periodontal pocket with a probing pocket >=5mm (up to 8 chips);
Treat every 3 months
dislodges < 48 hrs, replace
dislodges > 7 days, fully treated

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9
Q

What are the adverse effects of chlorhexidine gluconate

A

Toothache, URI, sinusitis

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10
Q

What are the active ingredients in OTC mouthwash

A

Cetylpyridinium chloride
Chlorhexidine
Essential oils
Fluoride
Peroxide

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11
Q

Which OTC mouthwash ingredient reduces bad breath

A

Cetylpyridinium chloride

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12
Q

Which OTC mouthwash ingredient helps control plaque and gingivitis?

A

Chlorhexidine and essential oils

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13
Q

Which OTC mouthwash ingredient helps prevent tooth decay

A

Fluoride

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14
Q

Which OTC mouthwash ingredient helps whiten teeth

A

Peroxide

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15
Q

What population should not use mouthwash and why

A

Children <6 due to risk of ingestion

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16
Q

How is dental calculus (calcified dental plaque) prevented?

A

Tartar control toothpastes

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17
Q

What ingredients are in tartar control toothpastes?

A

Zinc salts
Pyrophosphate
Sodium Hexametaphosphate

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18
Q

What are the mechanisms of topical fluoride

A
  1. Enhance remineralization of carious lesions before they become cavities
  2. Inhibition of demineralization
  3. Destroy enzymes in bacteria that produce acids that erode the teeth
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19
Q

Outline the fluoride supplement guidelines ages <6 months

A

None

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20
Q

Fluoride supplement guidelines 6 months - 3 years

A

<0.3ppm = 0.25 mg/day

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21
Q

Fluoride supplement guidelines 3 years to 6 years

A

<0.3ppm = 0.5mg/day
0.3-0.6ppm = 0.25mg/day

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22
Q

Fluoride supplement guidelines 6-16 year

A

<0.3ppm = 1mg/day
0.3-0.6ppm = 0.5mg/day

23
Q

What to note about gingivitis vs periodontitis AB treatment

A

Gingivitis: need to cover anaerobes if ulcerative vs simple (clindamycin, metronidazole, Augmentin)

Periodontitis:
Stage I-2 = topical
Stage 3-4 = oral
Immunocompromised = IV

24
Q

What are common dental pain medications

A

NSAIDs
Acetaminophen
Opioids

25
Q

What must be avoided when treating dental pain

A

XR or long acting opioids

26
Q

What should be done if dental pain is due to infection

A

Surgery to remove infected tissue

27
Q

What does postoperative pain lasting >3 days indicate

A

alveolar osteitis

28
Q

What is the preoperative pain management for acute dental pain

A

NSAIDs single dose 30-60 minutes prior to dental procedure +/- chlorhexidine gluconate

29
Q

What is the postoperative pain management for acute dental pain

A
  1. Chlorhexidine gluconate
  2. Ice/heat/rest
  3. NSAID +/- acetaminophen on scheduled basis

Mild - NSAID (400) or Acetaminophen (325)
Moderate - NSAID (800) + Acetaminophen (500)
Severe - NSAID (800) + Acetaminophen (325) + low dose opioid (no more than 3 days)

30
Q

What are the classifications of chronic oral face pain

A
  1. temporomandibular disorders
  2. Persistent idiopathic facial pain
  3. Atypical odontalgia
    *often associated with psychosocial problems
31
Q

What are the pharmacotherapy treatments for chronic oral facial pain

A

Carbamazepine
Lamotrigine
Baclofen
Tricyclic Antidepressants

32
Q

What medications cause Xerostomia

A

SSRI
Sulfonylureas
Respiratory agents (anticholinergics)
Thiazides
CCB
Urinary Antispasmodics
NSAIDs
Opioids
Ophthalmologic agents

33
Q

Non-pharm treatments of Xerostomia

A

Increase hydration
Humidification
Avoidance of irritating triggers

34
Q

OTC medications to treat Xerostomia

A
  1. Saliva substitutes:
    - Mouth Kote
    - Oasis mouth spray
    - Biotene gel
    - Salivart
  2. Mucosal lubricants
  3. Saliva Stimulants
35
Q

Rx med for Xerostomia

A

Pilocarpine
1. related to head-neck cancer treatment - 5-10 mg PO tid, may take 12 weeks to help
2. related to Sjogren’s - 5mg PO qid, may take 6 weeks to help

36
Q

Pilocarpine MOA

A

Cholinergic agonist
Increases parasympathetic activity
Increases secretion from salivary glands

37
Q

What are adverse issues of bruxism

A
  1. Jaw muscle hypertrophy
  2. Tooth wear and crack development
  3. Pain
38
Q

What are potential drug related causes

A
  1. Antipsychotics
  2. SSRI
  3. SNRI

Fluoxetine, Venlafaxine, Sertraline

Symptoms onset 3-4 weeks and take 3-4 weeks to subside after cessation

39
Q

What does “meth mouth” look like

A

Blackened
Stained
Rotting
Crumbling
Falling apart

40
Q

Potential etiology of meth mouth

A

Acidic nature of meth
Dry mouth - less protective saliva
Increased carbonated beverages
increased grinding
Not properly cleaning teeth

41
Q

Treatment of choice for pharyngitis

A

Penicillin

42
Q

Penicillin VK dosing

A

Adults: 500mg BID
Children: 50mg/kg/day in 3 doses
- both 10 days

43
Q

Penicillin benzathine dosing

A

Adults: 1.2 million units IM once
Children (<27kg): 0.6 million units IM once

44
Q

Amoxicillin dosing

A

Adults: 500mg TID
Children: 40-50mg/kg/day
- both 10 days

45
Q

How to treat epiglottitis if not maintaining airway

A

immediate endotracheal intubation

46
Q

Maintain airway and less than 6

A

endotracheal intubation

47
Q

Maintaining airway and >6

A

individual decision of intubation vs observation

47
Q

Adults without severe respiratory stress and <50% airway obstruction

A

Closely monitor in ICU w/o artificial airway

48
Q

Most common organisms - epiglottitis

A

H. influenza type B
Strep pneumoniae
GA strep
Staph aureus

49
Q

What should be done prior to AB administration for epiglottitis

A

Blood culture and (if intubated) epiglottic culture

50
Q

What empiric therapy for epiglottitis

A

Ceftriaxone or cefuroxime + vancomycin for 7-10 days
If allergy, Vancomycin + quinolone OR carbapenem

51
Q

Who gets DTaP and who gets Tdap

A

DTaP - peds (Infanrix, Daptacel)
Tdap - 7 or older (Boostrix, Adacel)

52
Q

At what ages do babies get DTaP

A

2, 4, and 6 months
15-18 months
4-6 years

53
Q

Variations of combo DTaP vaccines

A

Pediarix - DTaP-IPV-HepB
Pentacel - DTaP-IPV-Hib