Deck 11

Question 1

Brodifacoum is:

Answer 1

rodenticide

Question 2

Mechanism of action of DNOC (SINITRO-ORTHO-CRESOL):

Answer 2

Is the uncoupling of oxidative phosphorylation

Question 3

Describe organophosphate poisoning- ehiology of poisoning, mechanism of action, clinical symptomatology, therapy and chemical – toxicological analysis:

Answer 3

–> ETHIOLOGY- Are used in insecticides high toxicity:
MECHANISM- Inhibition of acetylcholine esterase leads to overabundance of acetylcholine at the neuro receptor.
SYMPTOMS-
*GIT: hypersalivation, abdominal spasms, diarrhea
*Respiratory: bronchoconstriction, Pulmunary edema, dyspnea
*Heart: bradycardia
eye: miosis
–> THERAPY- atropine, TLC and GC

Question 4

Describe screening method for determination of Aspergillus flavum in cereals:

Answer 4

In screening method, we use UV - lamp in the darkroom. Aspergillus flavus has a green fluorescent colour. not all strains of Aspergillus produce aflatoxins, Therefore the analysis must be done by screening

Question 5

CHTA consists of:

Answer 5

 Extraction
 Purification
 Detection

Question 6

Brucine is used as a detection solution for qualitative determination of:

Answer 6

NO3-

Question 7

PCB is determined by

Answer 7

GC (gas Chromatography)

Question 8

Polarography is

Answer 8

Electrochemical Method

Question 9

Which compounds have the ability of fluorescence?

Answer 9

Alfatoxin (Aspeugillus Flavus)

Question 10

Write down the OECD tests used for testing of new chemicals

Answer 10

 Acute Oral Test
 Reproductive test in mammals, birds and developmental studies
 Inhalation tests
 Skin sensitivity
 Carcinogenicity
 Mutagenicity
 Immunotoxicity
 Subchronic and chronic tests