Deck 1

Question 1

OECD (organisation for economic cooperation & development) test is used for testing new chemicals…

Answer 1

• acute oral toxicity test
• skin sensitivity test
• inhalation test
• repro test & developmental studies
• carcinogenicity & mutagenicity tests
• chronic & sub-chronic tests

Question 2

MCPA (methyl chloro phenoxy acetic acid -> herbicide) determined by method

Answer 2

TLC (thin layer chromatography):
- detection with bromthymol, blue - yellow stain on blue background

Question 3

Formaldehyde determined by

Answer 3

Steam distillation:
- fehling solution –> red ppt
- schiffs reagent –> red or red-violet colour

Question 4

Result of warfarin determination is which colour stain?

Answer 4

Blue (on yellow background)

Question 5

Dragendorf’s & Marquis’ agents are the detecting agents for determination of?

Answer 5

Alkaloids (in biological material by TLC)

Question 6

Warfarin -> mechanism of action

Answer 6

Anticoagulation action: antagonises vit. K & stops production of prothrombin in liver, prolongs clotting time of blood, damaging capillaries & causing haemorrhages and bleeding out

Question 7

Supermethrin (aka permethrin) used as an…

Answer 7

Insecticide (determined by GC)

Question 8

How is formaldehyde determined? How is it extracted?

Answer 8

• fehlings solution 1&2 (red clotting)
• steam distillation

Question 9

Specific antidote in warfarin poisining

Answer 9

Vit. K or K1

Question 10

MCPA used as

Answer 10

Herbicide & algicide