DAY4 Flashcards
asymptomatic or complain of epigastric pain, nv, hematemesis or melena.. inflammation
gastritis
rapidly developing, superficial lesions often due to NSAIDS, alcohol, h-pylori infection, and stress from severe illness
acute gastritis
autoantibodies to parietal cells… causes pernicious anemia due to lack of intrinsic factor which aids absorption of Vit B12, assoicated with other autoimmune disorders like thyroiditis
Type A Chronic gastritis
occurs in the antrum and may be caused by NSAID use or H pylori infection.. associated with increased risk of PUD and Gastric cancer
Type B Chronic gastritis (90 %)
causes of gastritis
nsaid use, alcohol, h.pylori infection
meds that block gastric acid secretions by blocking histamine receptors in parietal cells exceptions…
- Ranitidine (zantac)
- Famotidine (pepcid)
- Nizatidine (axid)
- Cetirizine (zyrtec)
- zyrtec is H1 blocker for allergies
pain: duodenal ulcer vs gastric ulcer
decrease with meals vs greater with meals
causes of Peptic Ulcer Disease (PUD)
h pylori, corticosteroid, nsaid, alcohol, tobacco
Duodenal: hpylori is 90%
Gastric: h pylori is 70%
dx: PUD
upper endoscopy with biopsy
h pylori testing - urea breath test
complications of PUD
hemorrhage, obstruction, perforation, intractable pain HOPI
56 year old women recently diagnosied with RA. 2 months later has abdominal pain worse with food.
- Gastric ulcer
- duodenal ulcer
- crohn
- ulcerative colitis
greater pain with meals is Gastric ulcer…
crohns and ulcerative are IBD…
over secretion of Gastrin from tumors in duodenum and pancrease resulting in unresponsive, recurrent gnawing, burning abdomnal pain as well as with diarrhea, nausea, vomiting, fatigue, weakness, weight loss and GI bleeding
Zollinger-Ellison Syndrome
hormones for digestion..(source to target)
- Gastrin:
- Secretin:
- Cholecystokinin
- Gastric inhibitory peptide:
- stomach to stomach
- duodenum to pancreas, liver
- duodenum to pancreas, GB
- duodenum to stomach
hormone that stimulates bile secretion in the liver
secretin
hormone that stimulates emptying of bile in the GB
cholecystokinin
functional disorder that is characterized by changes in bowel habits that increase with stress as well as by abdominal pain that improves with bowel movements:
chronic abdominal pain, discomfort, bloating, alteration of bowel habits, diarrhea or constipation or both
irritable bowel syndrome
Inflammatory bowel disease: crohns disease vs ulcerative colitis
anywhere from mouth to anus (skip lesions) vs
large intestines and anus (continuous lesions with bleeding)
heartburn 30 to 90 minutes after a meal, worsens with reclining, and often improves with antacids, sitting or standing.. sour taste, globus, unexplained cough, morning hoarseness
Gastroesophageal reflux disease (GERD)
symptomatic reflux of gastric contents into the esophagus (transient LES relaxation)
test for GERD
barium swallow: hiatal hernia
upper endoscopy with biopsy: rule out barretts esophagus
24 hr ph monitoring
abnormal change of the cells (metaplasia) in the lower portion of the esophagus
- pheochromocytoma
- zollinger-ellison syndrome
- barrett esophagus
- hiatal hernia
Barretts esophagus
- pheochromocytoma - tumor of adrenal medulla
- sollinger ellison syndrome - gastrin producing tumor
- hiatal hernia ST
unilateral, 4 to 72 hrs, pain with nausea, photophobia or phonophobia, may have aura; more common in women, triggered by food, light or sound
migraine headache
treatment for migraines
Triptan, nsaids; propranolol, topiramate)
diagnosis for migraines
POUND; pulsatile, oneday, unilateral, nausea, disabling
unilateral, 15mins to 3 hrs, repetitive brief headache, excruciating periorbital pain with lacrimation and rhinorrhea; more common in men
Cluster headaches
treatment for cluster headaches
100% O2, sumatriptan
bilateral, >30mins, 4 to 6 hours, constant, steady pain, most common
tension headaches
treatment for tension headaches
analgesics, nsaids, acetaminophen
classic vs common migraines
unilateral w/aura vs bilateral w/o aura
unilateral chest pain, dyspnea, unilateral chest expansion, decrease tactile fremitus, hyperresonance, diminished breath sounds, all on affected side; commonly in tall, thin, young males
pneumothorax P_THORAX pleuritic pain tracheal deviation hyperressonancee onset sudden reduced breath sounds absent fremitus xray shows collapse
subtypes of pneumothorax
- primary (tall thin young males)
- secondary ( to COPD, TB, trauma, iatrogenic)
- tension (shock or death)
treatment of tension pneumothorax - emergency
immediate needle decompression followed by chest tube placement
RESULT OF Virchow's triad: venous stasis (plane flights, bed rest, incompetent venous valves) endothelial trauma (surgery, injury to LE) hypercoagulability state (malignancy, pregnancy, OCP use)
deep vein throbosis
clot formation in the large veins of the extremities or pelvis
unilateral lower extremity pain and swelling; Homan’s sign (dorsiflex foot causes pain in calf)
DVT
test choice for DVT
doppler ultrasound