CVR 43 Flashcards
Name some ARB’s
angiotensin receptor blockers
(few side effects, widely accepted) block type 1 angiotensin II (AT1) receptors on bloods vessels
Azilsartan (Edarbi) Candesartan (Atacand) Eprosartan. Irbesartan (Avapro) Losartan (Cozaar) Olmesartan (Benicar) Telmisartan (Micardis) Valsartan (Diovan)
Effect of aldosterone on the heart?
contribute to abnormal left ventricle growth and hypertension
Spironolactone — the first and most widely used member of this class antagonist aldosterone
What do ACE inhibitors do
Angiotensin-converting enzyme (ACE) inhibitors are heart medications that widen, or dilate, your blood vessels. Inhibit formation of angiotensin 2
Benazepril (Lotensin) Captopril. Enalapril (Vasotec) Fosinopril. Lisinopril (Prinivil, Zestril) Moexipril. Perindopril (Aceon) Quinapril (Accupril)
Drugs used in heart failure
diuretics ACE beta blcokers aldosterone digitalis
ACE indication
heart failure NYHA I-IV
asympotmatic ventricular dysfnuction
LVEF < 35-40%
Contraindications of ACE
intolerance renal failure renal artery stenosis pregnancy renal insiffuiccny hyperkalemia hypotension
When are ARBs not indicated
with beta blockers. Used with pats intolerant to ACE