CVR 41 Flashcards
1
Q
4 ways to modify the effect of a drug
A
absorbtion
distribution
metabolism
excretion
2
Q
How is absorbtion changed
A
slowed or accelerated like when opiates slow motility but metoclopramide speeds it up.
3
Q
How is distribution changed
A
move the drug from binding sites like when NSAID displace warfarin from albumin increasing bleeding.
4
Q
How does St Johns Wort affect the Pill
A
makes the pumps more active reducing the amount of drug in the system (cyclospine0
5
Q
Metabolic interactions
A
Cyto P450 3A4 erythromycin inhibits the use of other drugs
6
Q
How are NSAID and Lithium carbonate interacting
A
NSAID reduce renal blood flow and reduce clearance can be toxic
