cv - lymphatic system Flashcards

1
Q

what makes up the lymphatic system

A

Network of organs, vessels and tissues

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2
Q

describe the accessory fluid

A

return route to the blood

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3
Q

the lymphatic system is vital to what other system in the body

A

immune system

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4
Q

it is complementary to what other body system

A

Cardiovascular system

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5
Q

what is lymph

A

Fluid of the system (clear, pale yellow) ~interstitial fluid; 32L/day drained into system; returns lost plasma proteins to bloodstream in lymphatic vessels

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6
Q

what is lymphatic tissue

A

Structures and organs containing lymphatic tissue – a specialised connective tissue that contains large numbers of lymphocytes

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7
Q

what is bone marrow

A

Stem cells develop into RBC & WBC

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8
Q

whats the 3 functions of lymphatic system

A

Drain tissue spaces of excess interstitial fluid and return it to the cardiovascular system.

Transport dietary lipids and lipid-soluble vitamins (A, D, E & K) from the GI tract to the blood

Protect the body from foreign cells, microbes and cancer cells through immune responses.

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9
Q

what are the smallest lymphatic vessel

A

lymphatic capillaries

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10
Q

explain lymphatic capillaries

A

Slightly larger than blood capillaries, closed-ended

Pressure in tissues will force fluid into them

Overlapping endothelial cells, like a one-way valve, so fluid not flow out

Found throughout body except in CNS, bone marrow, portions of spleen and avascular tissues.

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11
Q

lymphatic capillaries merge to form what

A

form larger vessels: lymphatic ducts

  • Thin walled and more valves than veins
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12
Q

lymphatic vessels periodically have what

A

lymph nodes

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13
Q

explain lymph nodes

A

Lymphocytes in capsular structure

The left thoracic duct—-> Left subclavian vein at junction with jugular

Right lymphatic duct —> Right subclavian vein

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14
Q

explain lymph flow

A

Unlike cardiovascular, system has no pump

Muscle contraction

1-way valves,

Respiratory pressure

Smooth muscle contraction in lymph vessel wall.

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15
Q

lymphatic organs can be divided into what

A

primary and secondary organs

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16
Q

what are the primary lymphatic organs

A

Thymus

Red bone marrow
- Provide appropriate environment where stem cells divide & mature into B & T cells

17
Q

what are the secondary lymphatic organs

A

Lymph nodes
Spleen
Lymphatic nodules

18
Q

secondary lymphatic organs are the sites where most what occurs

A

most immune responses occur

19
Q

explain the thymus structure

A

Two lobed organ
Between lungs, above heart

20
Q

what are the cells in the thymus

A

immature T cells
mature T cells

21
Q

explain immature T cells in thymus

A

migrate from bone marrow to cortex of thymus where multiply and mature

22
Q

explain mature T cells of thymus

A

then enter blood and populate lymph nodes, spleen and other lymphatic tissues.

23
Q

what are lymph nodes structure and how many and where located

A

~600 bean-shaped organs along lymph vessels

Scattered throughout the body
- Concentrated near mammary glands, axillae (armpits) & groin

24
Q

explain cells in lymph nodes

A

Contain plasma cells, mature B-cells, T-cells, dendritic cells and macrophages

25
Q

what do lymph nodes do

A

Filter lymph,
trap foreign substances
Macrophages & lymphocytes destroy most foreign substances

26
Q

explain germinal centres in lymph nodes

A

Aggregations of B lymphocytes

Rapidly proliferating and differentiating upon stimulation with antigen.

27
Q

explain the spleens shape and location

A

Oval, largest single mass of lymphoid tissue

On LHS between stomach & diaphragm

28
Q

name the 2 tissue types of the spleen

A

Two types of parenchymal tissue:
white pulp
red pulp

29
Q

explain the white pulp parenchymal tissue of the spleen

A

lymphatic – lymphocytes & macrophages surrounding central arteries

30
Q

explain the red pulp parenchymal tissue of the spleen

A

blood-filled venous sinuses and splenic cords with RBC, macrophages, lymphocytes, plasma cells & granular leukocytes

  • Destroys worn or defective blood cells & platelets
  • Stores platelets
  • Production of blood cells in foetal life

Remove if ruptured as severe i.p. (intraperioneal) haemorrhage & shock; red bone marrow & liver can take over functions.

31
Q

describe lymphatic nodules

A

Egg-shaped masses of lymphatic tissues

NOT surrounded by capsule

32
Q

Mucosa-associated lymphatic tissue (MALT) found is in what

A

GI tract
Urinary tissue
Reproductive tissue
Respiratory tissue

Some in large aggregates e.g., tonsils, Peyer’s patches (in ileum).

33
Q

how much of the fluid exchange across walls of capillaries goes to lymphatics

A

1/10 volume

34
Q

describe Fluid exchange across walls of capillaries

A

hydrostatic pressure out

osmotic pressure into capillaries