Crohn's, IBD and Ulcerative colitis Flashcards

1
Q

Presenting features of ulcerative colitis

A

diarrhoea
rectal bleeding
abdominal pain
- gone on for a long time

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2
Q

presenting features of Crohn’s disease

A

abdo pain
weight loss
growth failure
can have diarrhoea but not always

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3
Q

diagnosis of IBD (Crohn’s and UC)

A
History & Examination
Intestinal symptoms
Extra-intestinal manifestations
Exclude infection
Family History
***Growth and sexual development***
Nutritional status
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4
Q

skin changes in Crohn’s

A

ERYTHEMA NODOSUM

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5
Q

oral and perianal changes changes in crohns

A

ulcers - rolled edge

anal tags and fissures

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6
Q

lab investigations? - crohn’s

A
Full blood count & ESR
Anaemia
Thrombocytosis
Raised ESR
Biochemistry
Stool calprotectin >1800
Raised CRP 
Low Albumin
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7
Q

low albumin and crohn’s

A

leaking protein into the gut that leaks out into the stool

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8
Q

adult UC - distribution?

A

Proctitis

or left sided

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9
Q

child UC - distribution?

A

Pancolitis

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10
Q

adults crohn’s - most common

A

Isolated ileal

and Ileocolonic

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11
Q

Child crohn’s - most common

A

Upper GI / panenteric

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12
Q

Diagnosis and investigations

A
Radiology (especially Crohn’s disease)
MRI - small bowel imaging
Barium meal and follow-through (younger kids)
Endoscopy
Colonoscopy & Upper GI endoscopy
Mucosal biopsy
Capsule enteroscopy
Enteroscopy
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13
Q

capsule enteroscopy is good for

A

diagnosing IBD

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14
Q

ulcerative colitis on a colonoscopy

A

blood in stools
abdo pain

  • contact bleeding
  • crypt abscess - pus
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15
Q

crohns on a colonoscopy

A

serpiginous ulcers - slimy

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16
Q

granuloma sign of

A

crohns disease

17
Q

ulcerative colitis on histology features

A

disordered crypts

- pus

18
Q

methods of treatment for IBD

A
Anti-inflammatory  
Immuno-suppressive 
Biologicals ( Infliximab)
nutritional 
surgical
19
Q

Crohn’s treatment pyramid

A

Polymeric diet or oral prednisolone

  • Steroid sparing agents azathioprine /6MP or Methotrexate
  • Biologicals Infliximab / Adalibumab
  • surgery