Costanzo Phys Flashcards

1
Q

What part of the circulation is the most dynamic in size

A

Arterioles

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2
Q

What receptor found in arterioles causes them to constrict

A

α1 receptors

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3
Q

What receptor in arterioles causes them to relax

A

β2 receptors

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4
Q

What are the general category of chemicals that cause changes in arteriole size

A

Catecholamines

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5
Q

What is the volume of blood inside the arteries called

A

Stressed volume

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6
Q

What is the volume of blood inside veins called

A

Unstressed volume

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7
Q

How is blood flow to one area altered

A
  1. Increase CO
  2. Divert blood from other structures to it
  3. Combine 1 and 2
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8
Q

What is velocity of blood related to?

A

Flow/area

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9
Q

What is the major mechanism for changing blood flow in CV system

A

Increasing or decreasing arteriole resistance

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10
Q

The most susceptible variable in the resistance equation?

A

Radius

Stuff/(pi*r^4)

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11
Q

What is resistance to flow directly correlated to

A

Length of vessel (length inc = resistance inc)

Viscosity (hematocrit)

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12
Q

Which resistance system shows the system as a whole? Closed loop?

A

Parallel = system
-no decrease in pressure among organs

One loop = series (A->ariole->cap->vule->V)
-sum of pressures is sum of system

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13
Q

What are turbulent sounds of blood called

A

Kortokoff sounds

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14
Q

What are audible murmurs

A

Turbulent flow sounds caused by disruptions of laminar flow

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15
Q

Reynolds number less than what is laminar

A

2000

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16
Q

Anemia can cause what changes in blood flow

A

Decreased hematocrit means less viscosity means less resistance

17
Q

Thrombi cause what relating to blood flow

A

Decreased diameter means increased velocity means more likely turbulent flow

18
Q

At what part of a blood vessel is viscosity and blood cells lowest

A

Walls

19
Q

Where is the largest pressure drop seen

A

Small A to arterioles

20
Q

What causes the small dip in systolic pressure? (Dicrotic notch or incisura)

A

The aortic valve closing

21
Q

Stroke volume is…

A

The volume ejected from the LV in one stroke

22
Q

Why is pressure higher in large A than aorta

A

The pressure wave from the contraction travels faster than flow; the large A need to contract to keep the blood moving

23
Q

Where is pulse pressure lost

A

Arterioles due to increased resistance and more compliant vessels

24
Q

What changes do we see to BP in arteriosclerosis? Aortic stenosis? Aortic regurgitation?

A
  1. Hardened vessels are less compliant causing a larger change in pressure than normal
  2. Valve stenosis causes decreases pressure because less blood can leave the ventricle
  3. Same as stenosis
25
Q

Which portion of cardiac conduction ensures that the ventricles have time to fill

A

Slow conduction through AV node

26
Q

What are the components of normal sinus rhythm

A

SA node initiates, 60-100 bpm, correct sequence

27
Q

What phase is the upstroke?

A

0

28
Q

What is phase 1 of the cardiac AP

A

The initial repolarization

29
Q

What is phase 2 of cardiac AP

A

The plateau (longer in vent)

30
Q

What is phase 3 of cardiac cycle

A

Repolarization

31
Q

What is phase 4 of cardiac AP

A

Rest

32
Q

What ultimately controls the HR

A

The pacemaker cell with the fastest phase 4 depolarization

33
Q

What causes a latent pacemaker to take over

A
  1. SA node inhibited by drugs or disease
  2. Signal from SA node cannot reach the heart
  3. Latent pacemaker cell becomes faster than SA node