Connective Tissue

Question 1

What 2 things are Connective tissues derived from?

Answer 1

1) (UD) pluripotent mesenchymal cells (Mesodermal layer of embryo)
2) Haematopoietic Stem Cells

Question 2

What are examples of HSC? (3)

Answer 2

1) Monocytes
2) Mast Cells
3) Blood Cells

Question 3

Examples of Visible Fibres?

Answer 3

Collagen, Elastic and Reticulin

Question 4

Examples of Ground Substance? (2)

Answer 4

1) Glycosaminoglycans

2) Proteoglycans

Question 5

Three types of Connective Tissue?

Answer 5

1) Fibrous (L/D)
2) Fatty
3) Hard: (cartilage/bone)

Question 6

How is Collagen produced and assembled?

Answer 6

1) Fibroblasts secrete tropocollagen

2) TC assembles collagen extracellulary

Question 7

What are the 5 types of Collagen function?

Answer 7

1) Tendons and Skin
2) Cartilage
3) Liver/BMarrow/Spleen (reticulin)
4) Basement Membranes
5) Placenta

Question 8

Type and Difference of Fibrous Connective Tissue?

Answer 8

1) Loose: Widely space thin collagen, fibroblast and unstained GS
2) Dense: Tightly packed thick collagen, blast/cyte and unstained GS

Question 9

Components, function and stain of Reticulin (3)?

Answer 9

1) Type 3 Collagen and Fibrillar Collagen
2) Provides a supporting Scaffold for cells
3) Stained with Silver stain

Question 10

What is Elastic tissue made of and produced by (2)?

Answer 10

1) Elastic Fibres/ Sheets of Elastin

2) Fibroblasts

Question 11

Two types of Fatty CT?

Answer 11

1) White: Large cells with 1 fat globule

2) Brown: Globules of fat between Shoulder blades/back of new-born, and thermoreg

Question 12

Which 2 cell types make up Cartilage?

Bonus: Property?

Answer 12

1) Chondroblasts (Immature)
2) Chondrocytes (Mature)
(Avascular)

Question 13

What is found in Cartilage’s EC Fibre and Matrix?

Answer 13

1) Collagen and Elastin

2) GAG (Hyaluronic Acid) & PG (CS & KG)

Question 14

What is in Hyaline Cartilage?

Answer 14

Chondrocytes in lacunae surrounded by glassy amorphous matrix
(No Visible Fibres, Synovial)

Question 15

What is Perichondrium made of?

Answer 15

Collagen and Fibroblasts

Question 16

Where is Elastic Collagen found and is it visible?

Answer 16

1) Pinna of Ear and Epiglottis

2) Elastic Fibres visible in matrix

Question 17

Where is Fibro cartilage found and is it visible?

Answer 17

1) Pubic Symphysis and Annulus Fibrosus

2) Visible collagen fibres in matrix

Question 18

Where is Synovium found and how many layers?

Answer 18

Inside Joint capsules of Synovial joints
1-4 layers A: Phagocytes B) Rich in RER
[(Vary in shapes Squam to Cub) and very vascular and innervated]

Question 19

Where is smooth muscle found and properties?

Answer 19

1) Arterial wall, intestine and respiratory tract

2) Involuntary, fusiform, not striated/branched and central nucleus

Question 20

Are all collagen types of uniform thickness?

Answer 20

Type 1 displays variable

Question 21

Is Collagen either elastic or contractile?

Answer 21

No Collagen can’t stretch or contract

Question 22

What is unique about reticulin?

Answer 22

It is able to form branched fibres

Question 23

How does Hyaline tissue gain nutrients?

Answer 23

Nutrients diffuse from surrounding tissues