Bones Flashcards
What are Osteoblasts and Osteocytes derived from?
Embryonic Mesenchymal Cells
Secrete Osteoid (mineralised bone
What are difference of location between osteoblasts and osteocytes?
Osteoblasts: Found on bone surface secreting osteoid
Osteocytes: Trapped in bony matrix
What are Osteoclasts derived from? And where found?
Haematopoietic Stem Cells
Surface of bone –> Howship’s Lacunae
What are the 4 categorisation of bone type?
1) Origin: Primary and Secondary
2) Formation: Membranous and Endochondrial
3) Gross Appearance: Spongy/cancellous and Compact
4) Location: Osteons and Appositional
What is the main make up of secondary bone?
Formed as osteon with central Haversian canal with central blood vessels
(Surrounding concentric layers of Lamellar bone with Osteocytes)
What are the 2 methods of bone formation?
1) Intramembranous Ossification: Flat bones of skull/cortical bone shafts
2) Endochondral Ossification: All other types
What are the technical term for bone shaft and head?
Shaft: Diaphysis
Head: Epiphyses
What are the main cell types of synovium?
1) Type A: Phagocytic Action
2) Type B: Rich in RER and Secrete synovial fluid
What is a prominent feature of osteoclasts?
They are multinucleated
What is a potential function of osteocytes?
Might resorb formed bone matrix
What feature is found in Haversian canals?
Blood vessels
What bones are formed by intramembranous ossification?
Majority of cranial bones, flat bones of face, Clavicles
