Connective Tissue Flashcards
Connective tissue cells have a common __________ origin.
Embryonic
Mesoderm forms __________ cells
Mesenchymal
What 4 things do undifferentiated mesenchymal stem cells specialize and become?
Fibroblasts
Tenoblast
Chondroblast
Osteoblast
Fibroblast
Fibrocyte ligament
Tenoblast
Tenocyte tendon
Chondroblast
Chondrocyte cartilage
Osteoblast
Osteocyte bone
-blast
More metabolically active; CREATE Extracellular matrix
-cyte
Mature cell that MAINTAINS Extracellular matrix
Connective Tissue is made up of ______ + ____________ ______
Cells (**-blast or **-cyte) + Extracellular matrix (ECM)
What does the Extracellular Matrix (ECM) do?
Plays important role; determines tissue function
What are the 2 types of ECM?
Fibrillar
Interfibrillar
Fibrillar
Structural proteins
Interfibrillar
Gel-like ground substance
Fibrillar component: all connective tissues contain ________ _______.
Protein fibers
Name the 3 types of protein fibers
Collagen
Elastic
Reticular
Collagen (3 characteristics)
Made from collagen in tri-helical structure
Well organized
Resists tensile loads (very little stretch)
Elastic protein fiber (4 characteristics)
Made from elastin proteins
Ability to stretch
Develops tension
Returns to original length
Reticular protein fibers (2 characteristics)
Made from collagen fibrils (small fibers)
Poorly organized
Interfibrillar component is AKA
Ground substance
What does Interfibrillar component contain?
Proteoglycans
What are proteoglycans?
Protein core with glycosaminoglycans (GAGS) - “bottle brush”: attracts water
What are the 4 types of Connective Tissue?
Bone
Fibrous
Cartilage
Blood
(BBCF)
What are the types of Fibrous Connective tissue?
Dense and Loose