connective tissue Flashcards
what are the connective tissues?
blood, loose connective tissue, dense: bone, cartilage, tendon, ligaments
what is cell origin of ct
mesenchyme/mesoderm
loose connective tissue made of
fibroblasts, extracellular matrix (collagen and elastin fibers, fibronectin, laminin, ground substance)
ground substance
chains of glycosaminoglycans (GAGs) which hold water to reduce compressive force, proteoglycan complexed with - ions to also attract water, has core protein and chondroitin sulfate side chains. 90% of mass, 10% of weight. fills space
fibroblasts
secrete ground substance
GAG example
hyaluronic acid
adipocytes
fat-producing cells, starts as undifferentiated fibroblasts (mesenchyme, could form osteoblasts or myocytes as well)
Collagen (with types)
cross-linked chains.
1= large, used in dermis, bones, tendons,
2- not fibrous, used in hyaline cartilage
3= small fibers. arteries and muscles
4- found in skin
5- skin and hair
tendons vs ligaments
tendons attach muscle to bone, ligaments straddle joints. both made of collagen 1, few fibroblasts and little blood, tendons are more structured but ligaments less organized.
elastin is part of..
made of crosslinked fibers, makes up aorta, lungs, bladder, elastic cartilage, skin
cartilage is made of..
lacunae with chondrocytes which secrete ECM (type 2 collagen and extra - charged ground substance for max compression resistance). outer layer is dense perichondrium made of type 1 and fibroblasts
hyaline cartilage
made of type 2, cushions joints, trachaea, nasal cartilage
fibrocartilage makes up..
intervertebral disks, pelvic girdle (lots of collagen)
elastic cartilage makes up..
ear, epiglottis
calcified cartilage is found..
in vertebrae of chondrichthyes
intermembranous ossification forms..
skull and clavicle (dermato)
how does endochondral bone form?
osteoclasts eat away cartilage, blood enters, osteoblasts form structure (from diaphysis to epiphysis). bone forms in islands. ends stay cartilaginous
structure inside of bone
canaliculae - small channels for cells to communicate, haversian canal - holds blood vessels and nerves, ground substance in bone (secreted by osteoblasts) is osteioid. it is 65% mineral, 25% collagen 1
lacuna
cavity in bone made by vacated osteocyte
joint types
synarthroses (restricted movement, like skull) vs diarthroses (articulated)
spicules
areas of growth
osteon
a unit surrounding haversian canal
lamella
layer of mineral deposit
epiphyseal plate
growth plate of bone which remains cartilaginous upon ossification.