Communicable Diseases Flashcards

1
Q

Characteristics of viruses?

A

Smaller than bacteria, non-living, invade cells and multiply inside causing them to burst

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1
Q

Characteristics of bacteria?

A

Larger, prokaryotic, don’t have membrane-bound organelles, produce toxins to make you feel ill

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2
Q

How do you stain bacteria?

A

Gram-positive looks purple-blue under a microscope and Gram-negative appears red

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3
Q

What is a parasite?

A

An organism that feeds off a host at their expense

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4
Q

Characteristics of fungi?

A

Eukaryotic, found on plants, makes plants unable to photosynthesise and digest food, kills the plant

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5
Q

Name all the plant diseases?

A

Ring rot, Tobacco Mosaic Virus, Potato Blight, Black Sigatoka

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6
Q

Symptoms of ring rot?

A

Bacterial disease, Gram-positive, Effects the leaves, tubers and fruit, Destroys the crop and has no cure

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7
Q

Tobacco Mosaic Virus symptoms?

A

Viral infection, damages leaves making them look all discoloured, prevents photosynthesis, no cure, treat by cutting infected leaves, leads to crop loss

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8
Q

Potato blight?

A

Fungal infection, dark brown patches on leaves around edges going towards middle, remove infected plants, insecticides, prevent by cleaning equipment, spread plants far apart

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9
Q

Explain Black Sigatoka?

A

Fungal disease, turns leaves black, hyphae digests the cells, reduces crop yield, use fungicides to treat

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10
Q

Tuberculosis?

A

Bacterial disease, caused by mycobacterium tuberculosis, destroys the lung tissue and suppresses the immune system, take antibiotics to treat, spread by droplet inhalation

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11
Q

Explain bacterial meningitis?

A

Bacterial infection, effects the meninges of the brain, can spread to the rest of the body and causes blood poisoning, affects 15-19 year olds typically, a symptom is a red/purple rash appears once glass is pressed to skin, treated by antibiotics, can get vaccinated from it

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12
Q

HIV/AIDS?

A

Viral infection, destroys the immune system and makes people susceptible to other diseases, transmitted by exchange of bodily fluids, sharing needles and unprotected sex, use drugs to slow the process down, no cure or vaccine yet

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13
Q

Influenza?

A

Viral infection, targets ciliated epithelium cells involved in gas exchange, can be fatal, leaves always open for secondary infection, 3 strands of it (A, B and C) Can be prevented with vaccination, the virus can mutate

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14
Q

Malaria?

A

Protist, spread by mosquitoes as vectors, infects red blood cells, the liver and the brain, symptoms are like the flu, prevent spread by using mosquito nets

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15
Q

What type of mosquitoes spread malaria?

A

Anopheles (female mosquitoes)

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16
Q

What is ring worm?

A

Fungal disease, causes grey-white, crusty, infectious, circular areas on the skin, treated by anti fungal creams, spread by direct contact

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17
Q

Athlete’s foot?

A

Fungal disease, causes cracking, spread by contact on clothes or towels, treated with anti-fungal creams

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18
Q

What are the three types of direct contact?

A

Direct contact (kissing, STDs, skin), Inoculation (animal bite, break in skin), Ingestion (contaminated food)

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19
Q

Different types of indirect transmission?

A

Fomites (inanimate objects), Droplet inhalation and Vectors

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20
Q

Factors effecting transmission?

A

Overcrowding, Poor nutrition, Compromised immune system, Climate, Hygiene

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21
Q

Non-specific defenses of mammals?

A

HCL stomach acid, skin acting as a barrier, blood clotting, inflammatory response, mucus membranes, cilia, expulsive reflexes

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22
Q

Explain the inflammatory response?

A

Histamine (dilates blood, more leaky) and cytokines (attract phagocytes) are released. Red, high temps and swelling occurs

23
Q

Explain how blood clots?

A

An enzyme cascade is triggered by thromboplastin making a blood clot. Serotonin is released constricting blood flow to area. Clot dries and toughens

24
Physical plant defences?
Deposition of callose in the plasmodesmata blocking pores, lignin acting as barrier
25
Chemical defenses in plants?
Terpenoids, toxins and insect repellents
26
Describe the process of phagocytosis?
Phagocytes recognize non-human antigens, phagocyte engulfs pathogen becoming a phagosome, this combines with lysosome forming a phagolysosome, enzymes digest and destroy pathogen
27
What is an opsonin?
Chemicals that bind and 'tag' pathogens making more recognizable to phagocytes
28
What in an antibody?
A Y-shaped glycoprotein called immunoglobins which bind to specific antigens
28
What is it called when the antibody has bound to an antigen?
Antigen-antibody complex
28
Structure of an antibody?
2 heavy and 2 light chains, held together by disulfide bridges, variable region for antigen binding sites, constant region too, hinge for flexibility
28
Ways that antibodies defend the body?
Agglutination, Neutralization, Anti-toxins, Opsonin
28
What produces antibodies?
Plasma cells
28
Role of T helper cells?
Bind to APC's and produce interleukins
28
What do interleukins do?
Stimulates the activity of B cells for humoral immunity
28
What do memory cells contribute to?
The immunological memory
29
Role of T regulator cells?
They suppress the immune system once pathogen eliminated, prevents autoimmune disease
29
Where are B and T cells matured?
B cells = Bone marrow T cells = Thymus
29
Describe the process of cell-mediated immunity?
Macrophage APCs bind with a T helper cell to release interleukins and stimulate mitosis into T memory cells or T killer cells
30
What is clonal selection?
Selecting the best B cell for the particular antigen
31
What is clonal expansion?
The activated B cells dividing by mitosis into plasma and memory cells
31
Difference in primary and secondary immune response?
Primary can take days or weeks, secondary uses memory cells to produce correct antibody quicker, more efficient
31
What is an autoimmune disease?
When the body stops recognizing 'self' cells and attacks healthy body tissue
32
Examples of autoimmune diseases?
Lupus, arthritis and type 1 diabetes
33
How are autoimmune diseases treated?
Immunosuppressant drugs
33
Natural immunity?
Natural Active - The immune response Natural Passive - Antibodies from mothers milk/ placenta
34
Artificial immunity?
Artificial Active - Vaccination Artificial Passive - Antibodies injected
35
How does a vaccine work?
Dead/ inactive pathogens are injected into the blood, primary response triggered to produce antibodies and memory cells so that secondary response will be quicker
36
What is an epidemic?
When a communicable disease spreads rapidly to a lot of people at a local level
37
What is a pandemic?
When a disease spreads rapidly on a global level
38
Herd immunity?
When a significant number of the population have been vaccinated and have developed immunity, disease dies out
39
Different sources of medicine?
Willow is used for aspirin (painkiller), foxgloves is used for digoxin (heart disease) and extraction from mold developed penicillin
40
Pharmacogenomics?
A combination of drugs that work with your genetics and disease - personal medicine
40
What is synthetic biology?
Genetic engineering of modified bacteria
41
3 things that drugs need to be tested to find out?
Toxicity, effectiveness and dosage
42
Examples of antibiotic-resistant bacteria?
MRSA and C. diff