Chapter 3: Cell division Flashcards
Phases of the cell cycle?
Interphase which includes G1, S, G2, phases
What happens in G1 phase?
Cell increases in size, organelles like mitochondria and cytoplasm replicate
What happens in the S phase?
Synthesis phase, the DNA is replicated in the nucleus
What happens in the G2 phase?
Cell continues to grow in size, checks chromosomes for DNA replication errors, repairs them
Why do cells go to the G0 phase?
They’ve been differentiated and can no longer divide, damaged DNA or there are too many cells in the body
What does the G1 and G2 checkpoint do?
Checks if cell is big enough and has been replicated correctly without any errors
Explain the spindle-assembly checkpoint?
Also known as metaphase. Chromosomes are attached to spindles and get aligned along the equator of the cell. Necessary to pass or mitosis can’t happen
Order of mitosis stages?
Prophase, Metaphase, Anaphase and Telophase
Prophase in mitosis?
Chromosomes condense and thicken, this makes them visible. Nuclear envelope starts to break down. Spindle fibres start to form
Metaphase in mitosis?
Spindle fibres move chromosomes into the centre of the cell called the metaphase plate
Anaphase in mitosis?
Centromeres holding the chromatids together separate to either poles by the spindle fibres
Telophase in mitosis?
Chromatids now called chromosomes and assemble at poles. Nuclear envelope starts to form around them. then its cytokinesis.
Where does chiasmata take place and what is it?
Anaphase 1, it is the break and rejoining of chromatids due to them crossing over, cause DNA change and genetic variation
What is crossing over?
Takes place in Prophase 1 and it is the chromatids entangling because they were brought to close together
Where does independent assortment take place and what is it?
Metaphase 1, its chromosomes facing different directions and different poles, cause genetic variation
What happens in Telophase 2?
The chromosomes uncoil and form chromatids again
what is the level of organisation?
Specialised cells, tissue, organs, organ systems, organisms
How are erythrocytes specialised?
Red blood cells, flattened biconcave shape which increases SA:V. No nuclei which means more space for haemoglobin to carry oxygen. Flexible to fit through capillaries
How are neutrophils specialised?
White blood cells essential role in immune system. Multi-lobed nucleus easier to fit through small gaps to reach infections. Granular cytoplasm contains a lot of lysosomes to attack and break down pathogens