Clo2 Flashcards
What is the law of surface tension? And what is the relationship
LaPlace law- relationship between pressure and surface tension
What is the disease associated with excess surface tension that doesn’t permit proper inflation
Atelectasis- may collapse alveoli
With the alveolar capillary membrane (ACM), gas can move in the spaces of the venous capillary and alveoli due to
Gas diffusion
What causes left shift aka increased affinity
Increased pH
Decreased CO2
Decreased temp,
Decreased DPG
Abnormal Hb
What causes right shift aka decreased affinity
Decreased pH
Increased CO2
Increased temp
Increased DPG
What is the relationship between ventilation, CO2 and O2
When breathing, ventilation is the process of the intake of O2 and the removal of CO2
What is the most common cause of hypoxemia
V/Q (ventilation and perfusion) mismatch
Distinguish where the concentration of O2 vs CO2 is highest vs lowest
PaO2 is lowest in the cells
PaCO2 is highest in the cells
A patients primary drive to breathe comes from what
Central chemoreceptors (CCR)
What’s the relationship between surfactant and lung inflation
Surfactant reduces surface tension at the air-water interface in the alveoli, preventing collapsed lung and allow easy lung expansion.
If there is a decrease in surfactant, surface tension will increase and can cause lung collapse
Term for movement of matter from high concentration are to low concentration
Diffusion
What are the 3 anatomical barriers that exist at the alveolar capillary membrane (ACM) even though the diffusion membrane is thin
- Alveolar epithelium
- Interstitial space and its structures
- Capillary endothelium
