CLIPP 16 Flashcards

1
Q

name 3 reasons why children are at higher risk for dehydration

A

they have a higher surface area:body mass ratio

higher basa metabolic rates

higher percentage of body weight that is water

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2
Q

What are common symptoms of DKA?

A

vomiting

weight loss

dehydration

shortness of breath

abdominal pain

change in LOC

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3
Q

What are the 3 diagnostic criteria for DKA?

A

random blood glucose of > 200 mg/dL

venous pH < 7.3 or serum bicarb < 15 mEq/L

Moderate or large ketonuria or ketonemia

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4
Q

What is the pathophysiology of DKA?

A

decreased insulin causes counterregulatory hormones to be secreted

increased gluconeogenesis and lipolysis

increased glucose –> increased water in vessels –> increased water loss

increased free fatty acids –> ketone production

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5
Q

describe whether the following lab values in DKA will be increased, normal, or decreased: blood pH, serum Na+, serum K+, bicarb, creatinine, serum glucose, serum ketones, urine ketones

A

pH = decreased

serum Na = decreased (dilutional hyponatremia)

serum K = normal/elevated (depleted intracellular K+)

bicarbonate = decreased

creatinine = elevated (severe dehydration –> prerenal azotemia)

serum glucose = increased

Serum ketones = increased

urine ketones = increased

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6
Q

What are the 3 types of dehydration?

A

isotonic/isonatremic

hypotonic/hyponatremic

hypertonic/hypernatremic

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7
Q

over what time period (hours) shoudl patients with isotonic/isonatremic dehydration have their fluids replaced? Hypotonic/hyponatremic? Hypertonic/hypernatremic?

A

Isotonic/isonatremic = 12 hours

Hypotonic/hyponatremic = 24 hours

Hypertonic/hypernatremic = 48 hours

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8
Q

In DM 2, are insulin levels low, normal, or high?

A

Usually normal or high levels of insulin, but hyperglycemia exists due to insulin resistance (IR) of peripheral tissues.

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9
Q

when does the ADA recommend screening for DM in children?

A

10 years of age or at onset of puberty

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10
Q

What is the max score on the Glasgow Coma Scale? what score indicates aggressive intervention and management?

A

15 total

8 or less may require aggressive intervention and management

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11
Q

In a patient with dehydration and tachycardia, resuscitation with an IV fluid bolus is crucial. What type of fluid should be administered and at what rate?

A

isotonic saline (0.9%) at 20 mL/kg over 60 minutes

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12
Q

besides fluid administration, what important “drug” should be administered to a patient in DKA?

A

insulin

Fluid resuscitation itself will help lower the blood glucose, but only insulin will correct the metabolic derangements of DKA by suppressing lipolysis and ketogenesis.

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13
Q

What is the Holliday-Segar method for maintenance fluids?

A

100 mL/kg/day for the first 10 kg of body weight
50 mL/kg/day for the second 10 kg of body weight
20 mL/kg/day for each additional 1 kg of body weight

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14
Q

Why is it important to have hourly neuro checks in DKA?

A

to make sure the patient doesn’t develop cerebral edema

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15
Q

Why is it important to monitor I/O in DKA?

A

hydration status needs to be continually reassessed

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16
Q

Why is it important to administer insulin in DKA?

A

because insulin is the only way to reverse DKA

17
Q

Why is it important to monitor serum glucose every 60 minutes in DKA?

A

glucose is initially monitored every 60 minutes to assess DKA reversal (along with other metabolic labs)

18
Q

Why is it important to monitor Ca, Mg, and phosphorus in DKA?

A

DKA patients often become Mg and phosphorus depleted. When phosphorus is added, calcium must be monitored

19
Q

Why is it important to monitor pH via venous blood gas in DKA?

A

got to make sure the acidosis is resolving

20
Q

Why is it important to monitor urine ketones in DKA?

A

urinary ketones should decrease as acidosis resolves

21
Q

there are a lot of options for subcutaneous insulin regimens, but every insulin regimen has the same two components. What are they?

A

basal insulin: intermediate-long acting to maintain normoglycemia in the fasting tate

prandial insulin: short acting insulin taken before meals

22
Q

What is the differential diagnosis fo vomiting and altered mental status?

A

DKA
Toxic ingestion
GI obstruction
Increased intracranial pressure
Gastroenteritis
Appendicitis
Bacterial pneumonia
Pyelonephritis