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Board Prep - Veterinary Pharmacology > Clinical Pharmacology > Flashcards

Clinical Pharmacology Flashcards

1
Q

What are the 5 actions of antibacterial drugs?

A

Inhibition of cell wall synthesis
Impairment of cell membrane
Inhibition of protein synthesis
Inhibition of Nucleic acid
Inhibition of Folate cofactors synthesis

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2
Q

Examples of antibiotic that inhibit cell wall synthesis
PCBVC

A

Penicillin
Cephalosporin
Bacitranin
Vancomycin
Cycloserine

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3
Q

Examples of antibiotics that impairs the bacterial cell membrane
PCTGA

A

Polymyxin B
Colistin
Tyrothricin
Gramicidin
Amphotericine B

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4
Q

Examples of antibiotics that inhibits protein synthesis
ASTMLTV

A

Aminoglycosides
Spectinomycin
Tetracycline
Macrolides
Lincosamides
Tiamulin
virginiamycin

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5
Q

Antibiotics classified under Aminoglycosides
SDNGKA

A

Streptomycin
Di hydrostreptomycin
Neomycin
Gentamicin
Kanamycin
Apramycin

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6
Q

Antibiotics under macrolides
TESOC

A

Tylosin
Erythromycin
Spiramycin
Oleandomycin

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7
Q

Antibiotics under Lincosamides

A

Lincomycin
Clindamycin

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8
Q

Examples of antibiotics that inhibits Nucleic acid
QNRN

A

Quinolones
Novobicin
Rifamycin
Nitrofurans

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9
Q

Antibiotics under Quinolones
EON

A

Enrofloxacin
Oxalinic acid
Nalididic acid

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10
Q

Antibiotics under Nitrofurans

A

Nitrofarazone
Furazolidone
Furaltadone

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11
Q

Examples of antibiotics that inhibit Folate cofactor synthesis
SST

A

Sulfonamides
Sulfonamide-Trimethoprim
Trimethoprim

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12
Q

What do you call penicillin from non penicillinase producing bacteria ?

A

Natural penicillins

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13
Q

Examples of natural penicillins

A

Penicillin G
Penicillin V

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14
Q

Describe the action of Pen G

A

Long acting
✓ Gram - bacteria
✓ UTI

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15
Q

Describe action of Pen V

A

✓ Gram + infections

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16
Q

What are the categories of Penicillins?

A

Natural Penicillins
Penicillinase - stable penicillins / Anti staph
Broad spectrum

17
Q

Example of Penicillinase- stable penicillin Antistaph
CODMNQ

A

Cloxapenicillin
Oxapenicillin
Dicoxapenicillin
Methipenicillin
Natpenicillin
Quinapenicillin

18
Q

False substrates for penicillinase which protects penicillin antibiotics. Usually combined with Amoxicillin. CST

A

Clavulanic acid
Sulbactam
Tazobactam

19
Q

Penicillin antibiotics that are used to treat Gram - aerobes
✓ E. coli, Haemoproteus, proteus
× Klebsiella, Pseudomonas
AAH

A

Amoxicillin
Ampicillin
Hetacillin

20
Q

Penicillin antibiotics which are antipseudomonal. Usually combined with tobramycin or gentamycin. Aka. Carboxypenicillins
CIT

A

Carbenicillin
Indanyl carberricillin
Ticarcillin

21
Q

Penicillin antibiotics that works on Klebsiella, Enterobacter, Pseudomonas
PAM

A

Piperacillin
Azlocillin
Meziocillin

22
Q

Acid-labile penicillin antibiotics
PMT

A

Penicillin G
Methicillin
Ticarcillin

23
Q

During inflammation, penicillin can cross _ , which it normally cannot?

A

Blood brain barrier
Placenta
Mammany barriers

Board Prep - Veterinary Pharmacology (16 decks)

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