Clinical Key Question Flashcards

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1
Q

What is your clinical key question?

A

Should we use medication to treat depression?

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2
Q

How many people over 16 have shown symptoms of anxiety or depression in the UK?

A

19.7%

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3
Q

What are patients prescribed with while waiting for therapy?

A

Drugs by the doctor

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4
Q

How many items are prescribed yearly?

A

70.9 million

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5
Q

How much does it cost the NHS to treat those with depression yearly?

A

£672.5 million

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6
Q

How is using medication beneficial to treat depression?

A

People can go to work so the government receives taxes and don’t have to pay out some benefits

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7
Q

What does it mean if depression does have a biological cause e.g. monoamine imbalance?

A

You can treat depression with a medical intervention

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8
Q

What is an alternative to using medication to treat depression?

A

CBT therapy

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9
Q

What do drugs have?

A

Side effects

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10
Q

Why might using medication to treat depression not be very good?

A

Not long lasting

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11
Q

What does having an imbalance of neurotransmitters mean?

A

Depression

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12
Q

What does excess reuptake of monoamines lead to?

A

Depression

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13
Q

What is low serotonin linked to?

A

Low mood, sleep issues and erratic brain functioning

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14
Q

What is low dopamine linked to?

A

Anhedonia and lack of concentration

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15
Q

What is low noradrenaline linked to?

A

Lack of energy, changes in sleep

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16
Q

Why is it good that MAOIs stop MAO from doing its job?

A

Doesn’t break down the
monoamines and their number increases

Improves symptoms such as energy and
pleasure.

17
Q

What do drug treatments use?

A

Monoamine agonists

e.g. anti-depressants increase levels of monoamines

18
Q

What do SSRIs do?

A

Stops reuptake of serotonin so there is more in the synapse

Improves symptoms like anxiety

19
Q

What do high levels of MAO do?

A

Break down monoamines

20
Q

How does Geddes support the clinical key question?

A

Using drugs has a relapse rate of 18% so symptoms are less likely to return

21
Q

How does the Royal College of Psychiatry support the clinical key question?

A

50 to 65% of people treated with
antidepressants showed improvement so drugs are an effective treatment for depression

22
Q

How does the Royal College of Psychiatry conflict the clinical key question?

A

Drugs aren’t effective for a
significant minority (35-50%) suggesting other treatments, such as ECT or CBT, might be a
better treatment

23
Q

How does Nulman support the clinical key question?

A

Showed no negative effects on cognitive or language functions in
children whose mothers had undergone drug treatment for depression during pregnancy so it is safe and effective

24
Q

How does March support the clinical key question?

A

Suggested that for adolescents the best results are found by
combining drug treatment with CBT so we should be using drug therapy to
treat depression

25
Q

How does Muller conflict the clinical key question?

A

Found 76% of those who didn’t receive treatment for depression still recovered, and did not relapse

26
Q

How does Muller support the clinical key question?

A

24% of patients needed treatment, suggesting drug therapy is needed in some circumstances

27
Q

How does Rausch conflict the clinical key question?

A

Showed the success of SSRI treatment is dependent on the sufferer’s genes, suggesting another aspect to the biological substrate

28
Q

How does Hollon conflict the clinical key question?

A

Showed CBT had a longer lasting effect than drugs

29
Q

How does Kuyken conflict the clinical key question?

A

Found 60% of those who’d been given drugs relapsed so CBT may be a better alternative as it teaches you skills you can use in your own life