Biological (Genes) Explanation other than Neurotransmitters for Schizophrenia

Question 1

What is the biological explanation for schizophrenia other than neurotransmitters?

Answer 1

Genes

Question 2

What % of people does schizophrenia affect?

Answer 2

1%

Question 3

What % of DZ twins does schizophrenia affect?

Answer 3

17%

Question 4

What % of MZ twins does schizophrenia affect?

Answer 4

48%

Question 5

What type of genes are triggered?

Answer 5

Chromosome 5, Chromosome 22, or C4-A

Question 6

What do the genetic differences cause?

Answer 6

Changes in brain function

Alter functions of synapse (dopamine receptors)

Question 7

How does Kety support the biological (genes) explanation for schizophrenia other than neurotransmitters?

Answer 7

Found that the biological relatives of Schizophrenia patients had a higher rate of Schizophrenia

Question 8

How can the gene explanation be used alongside the neurotransmitter explanation for schizophrenia?

Answer 8

Genes cause the changes in glutamate/dopamine which causes
schizophrenia, so it would be a more holistic
explanation of Schizophrenia

Question 9

What does the biological (gene) explanation for schizophrenia other than neurotransmitters explain?

Answer 9

Trends of how it runs in families making it a credible and useful theory

Question 10

Why is it reductionist saying genes are the only cause for schizophrenia?

Answer 10

Concordance for MZ twins is not 100% which we would expect if it was purely genetic,
therefore showing that the environment plays a role too

Question 11

Why do we not always see the true impact of nature and nurture in twin studies?

Answer 11

Assumes MZ and DZ twins share equal amounts of environmental influence, but MZ are treated more alike especially as they must be the same sex.so we have an incomplete gene explanation for schizophrenia

Question 12

Why can we not use schizophrenia to support the biological (gene) explanation for schizophrenia other than neurotransmitters?

Answer 12

Small sample size means that the findings from that study might not
be representative of a wider population calling into question how effective it is as an
explanation of Schizophrenia in the world population

Question 13

What did researchers at Liverpool University find which conflicts the biological (genes) explanation for schizophrenia other than neurotransmitters?

Answer 13

Childhood trauma makes you three times more likely to develop schizophrenia, suggesting that there is a strong relationship
between the environment and the development of schizophrenia and it is not just due to
genetics