Biological Treatment for Schizophrenia (Drugs) Flashcards

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1
Q

What is the biological treatment for schizophrenia?

A

Drugs

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2
Q

What do drug (biological) treatments use to change the balance of neurotransmitters in the brain?

A

Psychoactive drugs

e.g. antipsychotics reduce the availability of dopamine

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3
Q

How do drugs work?

A

Block dopamine receptors in the brain minimising the effect of dopamine

Reduces positive symptoms e.g. hallucinations

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4
Q

How are drug (biological) treatments tailored to the schizophrenic patient?

A

Psychiatrists adjust the quantity of a drug for the level needed

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5
Q

How can drug (biological) treatments for schizophrenia be administered?

A

Syrup, tablet or injection

If patients forget to take them then medical
practitioners could inject the anti-psychotics

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6
Q

What 2 types of drugs are there?

A

Typical and atypical

The latter being the more modern treatments which tackle more than just Dopamine and can effect other neurotransmitters like Serotonin and Glutamate

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7
Q

When are drugs taken?

A

Regular basis to keep the symptoms under control

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8
Q

How long does it take for a drug to show the effects and for the symptoms to reduce?

A

About 10 days

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9
Q

How are psychoactive drugs available for treating mental disorders e.g. schizophrenia?

A

On prescription and patients will be monitored to ensure they are responding to the drugs

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10
Q

Why are there several different drugs to treat the same disorder e.g. schizophrenia?

A

May be necessary to
try several different ones until the drug that suits a particular patient best is found

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11
Q

What are examples of drugs to treat schizophrenia?

A

Chlorpromazine

Thorazine

Haloperidol

Trilafron

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12
Q

How do drug (biological) treatments improve patient’s quality of life?

A

Act relatively quickly allowing stabilisation of the patient’s condition during the acute
phase of illness e.g. schizophrenia

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13
Q

How do drug (biological) treatments have major benefits and avoid/reduce hospitalisation?

A

Allows patient to return to and function effectively in the community

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14
Q

How does Emsley support the biological treatment for schizophrenia (drugs)?

A

Found 84% of patients on anti-psychotic medications had at least a 50%
reduction in symptoms if they were given early enough

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15
Q

How does Kane support the biological treatment for schizophrenia (drugs)?

A

Found that antipsychotic drugs help approximately 80-85% of patients

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16
Q

How does Hogarty support the biological treatment for schizophrenia (drugs)?

A

Found relapse rates of 48% vs 80% without these types of medication

17
Q

How does Meltzer support the biological treatment for schizophrenia (drugs)?

A

Haloperidol gave significant improvements in all aspects compared to placebo

18
Q

What % of patients do not respond to drug treatments for schizophrenia?

A

60% so it is not an effective treatment as a large percentage of patients are not helped

19
Q

Why might the biological treatment for schizophrenia not be the most effective?

A

Drugs cannot cure the disorder, at best they help the individual manage the disorder so when you come off the medication the symptoms might reappear

20
Q

Why might people’s schizophrenia not be treated with drugs?

A

Anti-psychotics have serious side effects e.g. decrease in motivation and Tardive
Dyskinesia (involuntary movement of face and jaw), so schizophrenics may prefer not to take them

21
Q

How does Leiberman conflict the biological treatment for schizophrenia (drugs)?

A

Many patients stop taking their medication because of the severe side
effects

22
Q

How does Leucht conflict the biological treatment for schizophrenia (drugs)?

A

Found that drugs are good for treating ‘positive’ symptoms, however
comparative affects on ‘negative’ schizophrenia are marginal

Does not cover all aspects of schizophrenic symptoms

23
Q

How does Rosa conflict the biological treatment for schizophrenia (drugs)?

A

Found only 50% of patients complied with taking their anti-psychotics