Clinical Flashcards
What are the 3 types of Symptoms of Schizophrenia?
- Positive
- Negative
- Cognitive
What is Psychosis?
A general term for disorders that involve a loss of contact with reality
What is Schizophrenia marked by?
•Periods of remission where the patient has no symptoms •Followed by relapses where their symptoms reoccur
What is Schizophrenia?
- A psychotic disorder
* Where their ability to perceive, process + respond to environmental stimuli is impaired
What are Positive Symptoms in Schizophrenia?
Strange additions to normal behaviours
What are Negative Symptoms in Schizophrenia?
Loss of normal characteristics
What are Cognitive Symptoms in Schizophrenia?
Issues to do with information processing
What are the 4 Types of Positive Symptoms in Schizophrenia?
- Delusions
- Hallucinations
- Disorganised thinking/speech
- Abnormal motor behaviour/disorganised behaviour
What are Delusions as a Type of Positive Symptoms in Schizophrenia?
Bizarre beliefs which persist
What are the Different Types of Delusions as a Type of Positive Symptoms in Schizophrenia?
- Delusions of reference
- Delusions of grandeur
- Delusions of persecution
- Thought insertion
- Thought broadcasting
What are Delusions of Reference as a Type of Delusion as a Type of Positive Symptoms in Schizophrenia?
Patient believes that other peoples behaviour is directed specifically at them
What are Delusions of Persecution as a Type of Delusion as a Type of Positive Symptoms in Schizophrenia?
Believes that one is being plotted or conspired against
What is Thought Broadcasting as a Type of Delusion as a Type of Positive Symptoms in Schizophrenia?
Belief that others can hear their thoughts
What is Thought Insertion as a Type of Delusion as a Type of Positive Symptoms in Schizophrenia?
Person believes that their thoughts have been implanted by some kind of external force
What are the Cultural Differences of Delusions as a Type of Positive Symptoms in Schizophrenia?
- Delusions reflect pre-dominant themes + values of a persons culture
- In industrially advanced countries (America) patients delusions focus on sinister uses of tech - e.g. patients may report that they’re being spied on by their TV
- In Nigeria, mental illness is believed to be caused by evil spirits, so delusions may be in the form of witches
- So delusions differ according to the patient’s culture
- In some African cultures hallucinations are not seen as a sign of mental illness
- So different cultures may diagnose disorders differently
What are Hallucinations as a Type of Positive Symptoms in Schizophrenia?
- Perception of stimuli not actually present
- It can be visual, auditory, or olfactory
- Sometimes they will comment on the individuals character, usually in an insulting manner or they may give a command
What are the Cultural Differences of Hallucinations as a Type of Positive Symptoms in Schizophrenia?
- People from different cultures may interpret the voices that they hear differently
- Luhmann (2015) - found in some cultures the voices heard were harsh + critical, but in others they were seen as kind
- So symptoms of schizophrenia may vary from cultures
What is Disorganised Thinking/Speech as a Type of Positive Symptoms in Schizophrenia?
- Underlying with conscious thought that has an effect on a person’s language
- Patient’s speech is jumbled due to loose associations in thoughts - where 1 idea constantly triggers another, so they jump from topic to topic
What is Abnormal Motor Behaviour/Disorganised Behaviour as a Type of Positive Symptoms in Schizophrenia?
Agitated movement - such as repeating movements over and over again
What are the 6 Types of Negative Symptoms in Schizophrenia?
- Lack of energy + movement
- Social withdrawal
- Flatness of emotion
- Not looking after appearance + self
- Lack of pleasure in everyday things
- Speaking little
How do the Negative Symptoms in Schizophrenia Link to Psychology as a Science?
They are more objective as they may be more directly observable
What are the 3 Types of Cognitive Symptoms in Schizophrenia?
- Difficulties in concentrating + paying attention
- Problems with working memory
- Difficulties with executive functioning
What are the 3 Features of Schizophrenia?
- Onset
- Prevalence
- Prognosis
What is Onset as a Feature of Schizophrenia?
- Between late teens + mid 30s
- Peak onset is early to mid 20s in males, and late 20s for females
- The episodes develop gradually over time + may not be obvious at first
What is Prevalence as a Feature of Schizophrenia?
- Refers to how common a disorder is
- It is a universal illness
- The likelihood of developing schizophrenia is between 0.7 and 1%
- This is influenced by racial/ethnic background, residence + birth country
- People who experience social problems (poverty + unemployment) are more likely to develop schizophrenia
What is Prognosis as a Feature of Schizophrenia?
- Refers to likely course of the disease
- 25% of people who had a schizophrenic episode recover
- 50% of people have recurrent episodes
- 25% of people experience schizophrenic symptoms continually
- Life expectancy for person w/ schizophrenia is 10 years less than the average
- Males show higher proportion of negative symptoms + have longer duration of the disorder - these factors are associated w/ a poor prognosis
How does Onset as a Feature of Schizophrenia Link to Developmental Psychology?
Schizophrenia is triggered by some aspect of development during the years of late teens and mid 30s - either biological or social
How does Prevalence as a Feature of Schizophrenia Link to Individual Differences?
People who experience social problems such as poverty and unemployment are more likely to develop schizophrenia
How does Prognosis as a Feature of Schizophrenia Link to Individual Differences?
Males show more negative symptoms + have a longer duration of the disorder - these factors are associated with poor prognosis
How does Prognosis as a Feature of Schizophrenia Link to Cultural Differences?
The WHO international pilot study of schizophrenia suggests - patients w/ this disorder in developing countries have more positive prognosis than do patients in Western industrialised societies
How does Prevalence as a Feature of Schizophrenia Link to Cultural Differences?
Prevalence varies according to countries
What is a Neurotransmitter?
Chemicals that allow neurons to communicate with one another which allows our brains to think and feel so that our bodies are able to do things
What is Dopamine?
Neurotransmitter associated with functions, including motivation and feeling pleasure
What is the Dopamine Hypothesis?
Suggest that schizophrenia can be explained by changes of dopamine functioning in the brain
How can Schizophrenia be Explained by High Levels of Dopamine?
- Low levels of beta hydroxylase, so excess dopamine builds up in the synapses
- Excess dopamine receptors at synapses in the brain
- Due to hyper sensitivity of certain dopamine receptors
How are Low Levels of Serotonin Related to Schizophrenia?
Irregular serotonin activity = negative symptoms of schizophrenia
How are Low Levels of Dopamine Related to Schizophrenia?
Low levels of dopamine in mesocortical pathway = negative symptoms
How are High Levels of Dopamine Related to Schizophrenia?
High levels of dopamine in mesolimbic pathway = positive symptoms
What are Neurotransmitters (which aren’t serotonin or dopamine) Which have a Influence on Schizophrenia?
- GABA
* Glutamate
What are the Strengths of the Theory of Neurotransmitters as an Explanation for Schizophrenia?
- Explains positive + negative symptoms - increase of dopamine in mesolimbic pathway accounts for positive symptoms, decrease of dopamine in mesocortical pathway accounts for negative symptoms
- Backed up by evidence from drug treatment - antipsychotic medications for work by blocking dopamine receptors
- Testable evidence that excess dopamine plays a role in schizophrenia - people given Levodopa experience schizophrenic-like symptoms (e.g. hallucinations)
- PET scans in investigating dopamine levels in patients provide an objective measure of neurotransmitter functioning in areas of the brain
What are the Applications of the Theory of Neurotransmitters as an Explanation for Schizophrenia?
Many antipsychotic medications used to treat schizophrenia work by blocking dopamine receptors
What are the Weaknesses of the Theory of Neurotransmitters as an Explanation for Schizophrenia?
- It’s reductionist - Ignores other factors that may influence whether someone develops schizophrenia - biological, psychological + social factors
- Cannot prove that excess dopamine causes schizophrenia, instead it may be a symptom of schizophrenia
- Not all patients with schizophrenia respond to the drugs - Friedhoff (1980) found that some patients show no improvement after taking dopamine antagonists
- PET scans show that blocking dopamine receptors doesn’t always remove the symptoms
What did Brown and Birley (1968) Find which Suggests the Theory of Neurotransmitters as an Explanation for Schizophrenia
is Reductionist?
- Found that 50% of schizophrenic patients reported a major life event in the 3 weeks prior to the relapse
- Suggesting that social conditions may trigger relapse
What did Owen (1978) Show which Supports the Theory of Neurotransmitters as an Explanation for Schizophrenia?
- Post-mortem examinations of the brains of people with schizophrenia
- Showed that they had a higher density of dopamine receptors in the cerebral cortex
What does it mean if Schizophrenia is Genetic?
- People who are genetically related to schizophrenics should be more likely to have schizophrenia themselves
- The chances of them having schizophrenia is higher
What are the 3 Types of Research that have Investigated the Role of Genetics in Schizophrenia?
- Family studies
- Adoption studies
- Twin studies
What are Family Studies as a Type of Research that has Investigated the Role of Genetics in Schizophrenia?
- Investigate whether close biological relatives also have schizophrenia
- Problematic as the closer the relative the more likely they are to share the same environment
- So it’s difficult to separate out the effects of nature with nurture
What are Adoption Studies as a Type of Research that has Investigated the Role of Genetics in Schizophrenia?
- Useful as a genetic factor can be looked for in adopted children who have been apart from their biological parents
- Allows effects of nature to be separated from nurture which controls extraneous variable of environment
- The adopted children whose biological parents are schizophrenic have a higher risk of developing schizophrenia
What are Twin Studies as a Type of Research that has Investigated the Role of Genetics in Schizophrenia?
- Schizophrenia in MZ and DZ twins can be compared
- If a twin has schizophrenia then the concordance rate between MZ twins should be 100% whereas it should be lower in DZ twins as they only share 50% of their genetic material
What are Dizygotic (DZ) Twins?
- Non-identical
* Share 50% of their genes
What are Monozygotic (MZ) Twins?
- Genetically identical
* Share 100% of their genes
What were the Results from Gottesman and Shield’s (1966) Study which related to Twin Studies?
- Concordance rates for schizophrenia were higher in females compared to males for MZ and DZ twins
- Concordance rates higher for MZ+DZ twins for severe schizophrenia compared to mild
- Concordance rates for severe schizophrenia was much higher in MZ twins (75%) compared to DZ twins (22%)
What were the Conclusions from Gottesman and Shield’s (1966) Study which related to Twin Studies?
- Schizophrenia does have a biological basis, developing it is influenced by a persons gene
- However, not totally caused by genes as concordance rate for MZ weren’t 100% •Therefore genes are a risk factor for developing it but environmental triggers are necessary
What did Gottesman and Shield’s (1966) Investigate which related to Twin Studies?
Whether schizophrenia has a genetic basis for looking at concordance rates for schizophrenia and MZ and DZ twins
What are the Strengths of Genes as an Explanation for Schizophrenia?
- Evidence from Twin studies suggest that there is a significant genetic factor in schizophrenia (e.g. Gottesman + Sheild)
- Biological approach to explaining schizophrenia is associated with the medical profession + has scientific status + credibility
What are the Weaknesses of Genes as an Explanation for Schizophrenia?
- Research methods used to establish genetic links e.g. twin studies have flawed methodologies - as don’t take account that genes may function differently in different environments
- Reductionist as environmental factors may be involved in the development of schizophrenia - e.g. concordance rate in MZ twins for Schizophrenia is only around 40-50%, so if the illness was purely down to genetics, we’d expect the rate to be 100%
- Confusion as to which genes are responsible for predisposing a person to schizophrenia as there could be many, Wright (2014) suggested that 700 genes have been linked to schizophrenia
What are the Individual differences in the Genetic Explanation of Schizophrenia?
- Symptoms of schizophrenia are very diverse and not the same for everyone
- Biological view is unlikely to be a complete one as there are likely to be different factors associated with developing the disorder that may account for the various subtypes and presentation of symptoms
What is the Issue and Debate of Nature-Nurture in the Genetic Explanation of Schizophrenia?
- Diathesis-stress model argue that schizophrenia develops in those who have a biological predisposition to developing illness due to genetic’s (neurochemical or neuroanatomical factors)
- But who also have some sort of environmental trigger - suggest the cause is a combination of factors
What does the Diathesis-Stress Model of Schizophrenia Suggest about the Genetic Explanation?
A genetic disposition which becomes apparent when the individual becomes stressed by factors in their environment
How is Developmental Psychology Linked to the Genetic Explanation of Schizophrenia?
- Schizophrenia can be explained through the process of development
- Thomas (2010) suggests schizophrenia stems from abnormalities in early brain development
- Prenatal exposure to infection or lack of nutrition have been linked with schizophrenia (Opler and Susser (2005))
- Schizophrenia develops in late adolescence and early adulthood
What are the Similarities between the Neurotransmitter Explanation for Schizophrenia and the Genetic Explanation for Schizophrenia?
- Both reductionist
- Both are biological explanations in terms of the medical model
- Both have research evidence to support their theories
What is the Cognitive Explanation of Schizophrenia?
- Explain human behaviour in terms of information processing
- So, explains the symptoms of schizophrenia in terms of the patients thought processes
- Cognitive impairments play an important role in the development and maintenance of schizophrenia
What are the 2 Cognitive Factors which may Explain Schizophrenia?
- Problems with attention
* Problems with memory
What are the Problems with Attention as a Cognitive Factor which may Explain Schizophrenia?
- People with schizophrenia have attentional processes which work in a different way
- They don’t have normal functioning of these filtering processes, leading them to pay too much attention to irrelevant stimuli
- Preventing them from making sense of the world in the way that most people can
What does Frith (1979) Suggest which Supports the Problems with Attention as a Cognitive Factor which may Explain Schizophrenia?
- Inability to filter out unnecessary cognitive noise created by internal information processing
- Patient is unable to self monitor effectively, resulting in hallucinations or delusions as they don’t realise that their thoughts are self generated
- Patient experiences their own internal thought as an external voice
- Which explains the symptoms of hallucinations and delusions
What does Hemsley (1993) Suggest which Supports the Problems with Memory as a Cognitive Factor which may Explain Schizophrenia?
- People with schizophrenia aren’t able to activate relevant schemas
- They experience sensory overload, so they are unable to predict what will happen next, their concentration is poor + they attend to irrelevant aspects of the environment
- Their poor integration of memory + perception leads to disorganised thinking and behaviour
What are the Problems with Memory as a Cognitive Factor which may Explain Schizophrenia?
- There is a substantial breakdown in the relationship between memory and perception in schizophrenics
- Which is linked to schemas, as relevant schemas are not triggered in people w/ schizophrenia
What is the Research by McGuigan (1966) which Supports the Cognitive Explanation for Schizophrenia?
- Found that the larynx of patients with schizophrenia was active during the time they were experiencing auditory hallucinations
- Suggesting that they mistook their own inner speech for that of someone else
What is the Research by McGuire (1996) which Supports the Cognitive Explanation for Schizophrenia?
Found schizophrenics to have reduced activity in the parts of the brain involved in monitoring inner speech
What is the Research from PET Scans which Supports the Cognitive Explanation for Schizophrenia?
- Show under activity in the frontal lobe of the brain of people suffering from schizophrenia
- Which is linked to self monitoring
- Providing biological support for this explanation
What are the Strengths of the Cognitive Explanation for Schizophrenia?
- It explains some of the key problems associated with schizophrenia, e.g. it explains the symptom of delusions + hallucinations + disorganised behaviour
- It is supported by research evidence
- Useful in developing effective treatments which have helped many people with mental disorders by alleviating the symptoms and improving their lives - e.g. Morrison (2014) found that cognitive therapy reduced psychiatric symptoms + is safe for people with schizophrenia
- It is less reductionist as it includes the idea that delusions are triggered by strange sensory experiences that arise from biological problems, suggesting a complex interaction between biological and cognitive causes of schizophrenia
What are the Weaknesses of the Cognitive Explanation for Schizophrenia?
- Difficult to find out whether the cognitive problems are a cause of their disorder or an affect, As they may play a role in causing schizophrenia or schizophrenia itself may cause the cognitive problems
- It is reductionist as it underestimates genetic factors, stressful life events and social factors in the development of schizophrenia
- Many brain-damaged patients have problems with attention or the relationship between memory and perception, but they failed to develop the symptoms of schizophrenia, which challenges the cognitive explanations
What are the Similarities between the Genetic Explanation and the Cognitive Explanation for Schizophrenia?
- Both supported by research evidence
- Both look at human body as part of the explanation, as 1 looks at memory and the other looks at genes
- Both reductionist as they underestimate the other factors into schizophrenia - such as social and environmental
What are the Differences between the Genetic Explanation and the Cognitive Explanation for Schizophrenia?
- Cognitive explanation can be more useful as it leads directly to treatment
- Cognitive looks at memory + attention as part of the explanation, whereas genetic looks at the biological inherited genes as part of the explanation
- Genetic can show cause + effect link between genes + schizophrenia, whereas the cognitive symptoms shown may be a symptom of schizophrenia rather than a cause
What is the Health and Care Professions Council (HCPC)?
- Clinical practitioners must register with this
* It sets standards which practitioners must meet in order to remain registered with the HCPC
What are the 7 Standards Set Out by the HCPC for Clinical Practitioners?
- Character
- Health
- Standards of proficiency
- Standards of conduct, performance + ethics
- Standard for continuing personal development
- Standards of education and training
- Standards for prescribing
What is Character as a Standard Set Out by the HCPC for Clinical Practitioners?
- Registrants provide credible character references from people who have known them for at least three years
- Considering any criminal convictions and their character traits
What is Health as a Standard Set Out by the HCPC for Clinical Practitioners?
- Provide info every two years when they re-register about their general health
- Provide info on any health issues that they have only if it’s likely to affect their ability to practice safely
What are the Standards of Profficiency as a Standard Set Out by the HCPC for Clinical Practitioners?
- There are a set of specific expectations for practitioners psychologists
- E.g. professional autonomy + accountability, delivery of strategies for meeting health + social care needs
- Specific requirements within each standard to be demonstrated by practitioners in different areas of psychology
What are Standards of Conduct, Performance and Ethics as a Standard Set Out by the HCPC for Clinical Practitioners?
- List of 14 guidelines that practitioners must adhere to in their clinical practice
- Including points such as maintaining confidentiality in work with service users, referring on to others when necessary, and only acting within the limits of their own knowledge
What are Standards for Continuing Personal Development as a Standard Set Out by the HCPC for Clinical Practitioners?
- Professionals expected to take part in + document regular training that they undertake to develop their own practice
- Including training events, evidence on how they’ve changed their practice, and an evaluation of the effectiveness of these changes
What are Standards of Education + Training as a Standard Set Out by the HCPC for Clinical Practitioners?
•Set of minimum levels of qualification specified before people can register to practice in
different areas of health + care professions
•Registrants must be able to evidence at least a master degree with bps qualification in the area of practice they will be working in
•HCPC sets out standards for training courses
What are Standards for Prescribing as a Standard Set Out by the HCPC for Clinical Practitioners?
- These standards set out safe practice for prescribing medication by health and care professionals
- Including the required knowledge and training to be able to prescribe within professional practice
What are the 2 Treatments which can Help People with Schizophrenia?
- Drug treatment
* Cognitive treatment
What is Drug Treatment for Schizophrenia Based on?
- The medical model of mental disorder
- Where mental disorders are seen as an illness + assumed they have biological causes
- Treatments are physical in nature
What are the Drugs used in Treatment for Schizophrenia Known as?
Anti-psychotic drugs
How does the Dopamine Hypothesis Explains how Drug Treatments for Schizophrenia Work?
Schizophrenia results from abnormally high levels of dopamine
How did the 1st Anti-Psychotic Drug (Phenothiazine) Explain how Drug Treatments for Schizophrenia Work?
- Blocking receptors for dopamine
- So, effects of dopamine aren’t picked up by the Brain
- However, there were side effects - shaking, muscle tremors, jerky movement
What are the New Drug Treatments for Schizophrenia and How do they Work?
- Clozapine - acts by blocking serotonin receptors
* Olanzapine + risperidone - have fewer side effects + more effective - known as ‘atypical’ drugs
What are the Strengths of Drug Treatment for Schizophrenia?
- Effective in reducing symptoms + more effective than any other form of therapy as reduces symptoms quickly
- Useful w/ assistance of antipsychotic drugs
- Allowed patients to live relatively normal lives - prior to phenothiazine, schizophrenia was considered untreatable
- Appropriate as it has more of genetic basis - main drugs used to treat schizophrenia block dopamine receptors, so appropriate to use as they target parts of physiological system that function abnormally in Schizophrenia
What did Meltzer (2004) Find which Supports that Drug Treatment is Effective in Reducing Symptoms of Schizophrenia?
Haloperidol gave significant improvements in all areas of functioning compared to placebo
What are the Weaknesses of Drug Treatment for Schizophrenia?
- It’s reductionist - ignores psychological + social factors
- Effectiveness + usefulness of drug therapy is limited - it is palliative - it suppresses the symptoms of the disorder without addressing the underlying causal processes - patients have to take drugs for many years
- Unethical - drugs often produce side effects + some patients unable to give consent + may lead to addiction + dependency
- Relapse is a problem - drugs don’t offer a long term cure as they don’t address the cause of the problem
- Some patients are resistant to drugs
- Most common drugs aren’t effective in treating the negative symptoms of schizophrenia
How is Drug Treatment for Schizophrenia an Issue of Social Control?
- Drug treatment can be looked down on in society as it’s considered that you need to alter their behaviours to become more ‘normal’ - social norms in society
- Cannot assume everyone has same symptoms + severity of symptoms due to labelling them ‘schizophrenic’
- Pharmaceutical drug company’s want money
Why is Drug Treatment the Most Common Biological Treatment for Schizophrenia?
- Dopamine hypothesis is widely accepted explanation for schizophrenia
- Suggests that schizophrenia may result from high levels of dopamine
- So, it follows the most common form of biological treatment for schizophrenia is drug therapy
What does the Cognitive Model of Abnormality Assume?
- Mental disorder is created by errors in thinking
* Thoughts influence emotions + feelings
What do Cognitive Behavioural Therapies Attempt to do?
Attempt to change maladaptive behaviour by changing the way people think
What does the Cognitive Behavioural Therapy Assume?
- Patients have irrational thoughts + beliefs about themselves + the world
- Thoughts + beliefs are negative, self-defeating + contribute to development of mental disorders
How do Therapists using Cognitive Behavioural Therapy Try to Change the Patients Behaviour?
- Focusing on the present symptoms
- Looking at how the person thinks about how an event affected them - what they felt + how they behaved
- Challenge negative thoughts + change them for more realistic + positive thoughts
- Person will feel better + behaviour will change
What is the Aim of Cognitive Behavioural Therapy when Treating Schizophrenia?
Reduce the stress felt by the patient with schizophrenia + allow them to help them mange + understand their symptoms
What are the 3 Techniques Used in Cognitive Behavioural Therapy for Schizophrenia?
- Belief modification
- Focusing + reattribution
- Normalising the experiences of the person w/ schizophrenia
What is Belief Modification as a Technique Used in Cognitive Behavioural Therapy for Schizophrenia?
Delusional thinking is challenged
What is Focusing + Reattribution as a Technique Used in Cognitive Behavioural Therapy for Schizophrenia?
- To help w/ hallucinations (auditory)
* Therapist aims to show that the voices are self-generated + don’t need to be feared
What is Normalising the Experiences of the Person with Schizophrenia as a Technique Used in Cognitive Behavioural Therapy for Schizophrenia?
Psychotic symptoms are looked at as more normal to reduce the fear related to them
What are the Strengths of Cognitive Behavioural Therapy as a Treatment for Schizophrenia?
- Useful as effective in treating - patients show increase in coping skills + decreased hallucinations + delusions
- Most ethical - empowers patients by educating them in self-help strategies + they have more control over the process - allows patients to be more independent
- Strategies learned cab be incorporated into a patients life - so it’s a useful treatment
What are the Weaknesses of Cognitive Behavioural Therapy as a Treatment for Schizophrenia?
- Reductionist - doesn’t address the underlying cause of the mental disorder as it overlooks biological causes
- Not effective - patient suffering severe schizophrenia may lack problem solving skills + don’t have an insight into their condition
- Effectiveness is hard to judge - control treatments are sometimes given by non-experts, so the use of inadequate control treatment conditions may explain some of the findings
What did Sensky (2000) Find which Supports that Cognitive Behavioural Treatment is Effective in Treating Schizophrenia?
- He compared CBT w/ non-specific ‘befriending interventions’ for patients w/ schizophrenia
- Found that CBT was more effective in reducing both positive + negative symptoms of schizophrenia
How does Cognitive Behavioural Therapy Link to the Issue of Social Control?
- CBT can be seen as an agent of social control, so patients thoughts may be changed to fit into social norms
- Superficial way of trying to get patients to act normally without actually addressing the problem
- But, by alleviating the symptoms, it makes the patient much more independent
What are 2 Similarities Between Cognitive Behavioural Therapy and Drug Treatment as Treatments for Schizophrenia?
- Both supported by research evidence - e.g. Sensky, Meitzar
- Both are useful as they allow people to live independent lives
- Both ignore social factors
What are 2 Differences Between Cognitive Behavioural Therapy and Drug Treatment as Treatments for Schizophrenia?
- Drug Therapy is more reductionist than CBT, as it focuses purely on biological treatment , where CBT looks at cognitive + behavioural
- CBT can be considered more ethical than drug therapy
What is a Review Article?
Summarises previously published studies
Why are Review Articles Useful?
- Looks at recent major advances + discoveries
- Looks at significant gaps in research
- Looks at current debates
- Looks at ideas of where research might go next
What are the Strengths of Review Articles?
- Generate new ideas about where research should go next
- Can close significant gaps in research
- Draws together wide body of data
- Includes recent major developments
What are the Weaknesses of Review Articles?
Has practical problems - validity and reliability may be interpretative if original studies had flaws
What is the Aim of the Contemporary Study for Schizophrenia by Carlsson (2000)?
Review research to investigate:
•Use info on psychosis + neurotransmitter functioning to produce new antipsychotic drugs that are more effective w/ fewer side-effects
•Show neurotransmitter functioning in specific brain areas
•Investigate neurotransmitter functioning + psychosis, beyond the dopamine hypothesis
What is the Procedure of the Contemporary Study for Schizophrenia by Carlsson (2000)?
- Literature review
- Methods + findings of studies to do w/ neurotransmitter interactions in schizophrenia are analysed
- Including studies using rodents to test neurotransmitter functioning + related brain structure functioning, studies on people w/ acute schizophrenia + people with schizophrenia in remission, studies which used brain scans to investigate psychosis
What were the Key Points about Dopamine from the Literature Review of the Contemporary Study for Schizophrenia by Carlsson (2000)?
- PET scans provide evidence to show high levels of dopamine related to psychosis - e.g. Abi-Dargham (1998) + Breier (1997)
- Supporting the dopamine hypothesis
- However interactions with other neurotransmitters (e.g. noradrenaline, serotonin, acetylcholine, glutamate, + GABA) may be related w/ schizophrenia
What were the Key Points about Glutamate from the Literature Review of the Contemporary Study for Schizophrenia by Carlsson (2000)?
- Low levels of glutamate play a role in schizophrenia
- Lodge (1989) - shows that PCP can induce psychosis by inhibiting the action of glutamate in the brain
- Glutamate failure in cerebral cortex may lead to negative symptoms of schizophrenia, •Glutaminergic in the basal ganglia could be responsible for positive symptoms
What were the Key Points about Dopamine and Glutamate from the Literature Review of the Contemporary Study for Schizophrenia by Carlsson (2000)?
- Some research has found an interaction between dopamine and glutamate
- Reduced levels of glutamate is associated with increased dopamine release
What were the Key Points about Serotonin from the Literature Review of the Contemporary Study for Schizophrenia by Carlsson (2000)?
- Serotonin may be implicated in schizophrenia
- Serotonin levels are related to dopamine
- Clozapine works by reducing dopamine and serotonin levels in the brain
- NMDA antagonists, which limit glutamate, seem to stimulate serotonin levels
What were the 2 Main Theories About the Causes of Schizophrenia from the Contemporary Study for Schizophrenia by Carlsson (2000)?
- Whether high levels of dopamine (hyperdopaminergia) cause schizophrenia
- Whether low levels of glutamate (hypoglutamatergia) cause schizophrenia
What was the Conclusions from the Contemporary Study for Schizophrenia by Carlsson (2000)?
- Glutamate deficiency may explain increased dopamine responsiveness
- Glutamate deficiency should be studied
- Increased serotonin activity is found in people w/ schizophrenia - dopamine + serotonin contribute to the positive + negative symptoms
- More focus on other neurotransmitters is needed (e.g. GABA, acetylcholine, etc)
- May be different subpopulations of those w/ schizophrenia, where it’s caused by different abnormal levels of different neurotransmitters - this has implications for treatment
What are the Strengths of the Secondary Data from the Contemporary Study for Schizophrenia by Carlsson (2000)?
- Provides an overview of key findings in the area
- generate new ideas about where research should go next
- Closes significant gaps in research
- Draws together wide body of data - allowing a large amount of info to be brought together quickly
- Because of the extensive nature of material covered, the conclusion drawn is likely to be valid
- Ethical - no direct ethical issues
What are the Weaknesses of the Secondary Data from the Contemporary Study for Schizophrenia by Carlsson (2000)?
- Studies rely on secondary data from many other studies
- The validity and reliability of Carlsson’s study may be affected by any research issues in the original studies
- So, any conclusions from his study may be problematic
What are the Strengths of the Original 33 Studies from the Contemporary Study for Schizophrenia by Carlsson (2000)?
- High reliability - studies cited by Carlsson are lab experiments - many are animal + PET scans using standardised procedures + controlled
- High validity - Carlsson considered glutamate as a possible contribute to schizophrenia (another hypothesis), he argues both hypotheses may be true + research should continue in both (evidence seems to suggest this), he questions the validity of the dopamine hypothesis he himself developed in 1950s, Sendt (2012) literature review supports Carlsson’s findings
What are the Weaknesses of the Original 33 Studies from the Contemporary Study for Schizophrenia by Carlsson (2000)?
- Low generalisability - some findings come from animals - so may not generalise to humans, culture may influence the type of auditory hallucinations (Luhrman, 2015), may be time locked (1999/2000) so research may no longer be representative of state of scientific ideas
- Unethical - issues of deception + risk as patients don’t know if they’re being given the real drug or placebo, studies use humans - with or without schizophrenia being given amphetamines or PCP or other drugs that increased psychotic symptoms
What are the Applications from the Contemporary Study for Schizophrenia by Carlsson (2000)?
- Useful in developing antipsychotic drugs
- Glutamate antipsychotics are still in development (Papanastasiou et al, 2013) could bring relief to people who don’t respond well to typical antipsychotics
- Improved dopaminergic drugs that have fewer side-effects based on better understanding of dopamine pathways + new atypical drugs that affect other neurotransmitters, like serotonin and glutamate
What are the Issue and Debates about Psychology as a Science in the Contemporary Study for Schizophrenia by Carlsson (2000)?
- Use of scientific methods- e.g. PET scans
- High validity - looks at a wide range of studies
- Uses animal studies which aren’t generalisable
- Not valid data - review article uses secondary data which might have flaws
- High validity + credibility- Breier et al (1997) produced objective data
What are the Issue and Debates about Practical Issues in the Design and Implementation of Research in the Contemporary Study for Schizophrenia by Carlsson (2000)?
- Difficult to study functioning of neurotransmitter in the brain
- So, neurotransmitters which are easiest to study (dopamine + serotonin) tend to be most researched and others which are important tend to be ignored
What are the Issue and Debates about Reduction in the Contemporary Study for Schizophrenia by Carlsson (2000)?
- This research is purely biological as only focuses on neurotransmitters, so it ignores social + cognitive factors
- But, research uses many different studies to draw its conclusions (rodent studies, PET scans), as it generates such a wide range of evidence it can be considered somewhat holistic, also looked at many different neurotransmitters
What are the Issue and Debates about an Understanding of How Psychological Understanding has Developed Over Time in the Contemporary Study for Schizophrenia by Carlsson (2000)?
- Further research suggested by the article will lead to more changes
- Methods of investigating neurotransmitters have become more sophisticated overtime
- Further research found that there is an interaction between dopamine + glutamate, as reduced level of glutamate is associated with increased dopamine levels
What are the Issue and Debates about the Use of Psychological Knowledge Within Society in the Contemporary Study for Schizophrenia by Carlsson (2000)?
- The research suggests areas for further research which can be used to inform further treatments for schizophrenia
- Future research as different sub populations have abnormal levels in different transmitters, not just dopamine
What is the Aim of the Longitudinal Study for Schizophrenia by Sensky (2000)?
Compare cognitive behavioural therapy (CBT) w/ non-specific ‘befriending interventions’ for patients w/ schizophrenia in effectively reducing positive symptoms of schizophrenia
What is the Design of the Longitudinal Study for Schizophrenia by Sensky (2000)?
- Randomised controlled design
- Patients allocated to one of two groups: A cognitive behavioural therapy group or an non-specific befriending control group
What were the Participants of the Longitudinal Study for Schizophrenia by Sensky (2000)?
- 90 patients - 57 from clinics in Newcastle, Cleveland and Durham and 33 from London
- They had a diagnosis of schizophrenia that had not responded to medication
- Aged 16 to 60 years
What were the Results of the Longitudinal Study for Schizophrenia by Sensky (2000)?
- Both interventions resulted in significant reductions in positive and negative symptoms and depression
- At the 9 month follow-up evaluation, patients who had received cognitive therapy showed greater improvements on all measures
What were the Conclusions of the Longitudinal Study for Schizophrenia by Sensky (2000)?
CBT is effective in treating negative + positive symptoms of schizophrenia that are resistant to standard antipsychotic drugs, w/ its efficiency sustained over 9 months of follow-up
What was the Procedure for the
Cognitive Behavioural Therapy Group of the Longitudinal Study for Schizophrenia by Sensky (2000)?
- Normal routine of CBT used - engaging with patient, examining antecedents of psychotic disorder, developing a normalising rationale + treatment of other disorders
- Specific techniques for positive symptoms of schizophrenia used
- Patients helped to change their beliefs + taught coping strategies to deal with the voices
What was the Procedure for the Befriending Group of the Longitudinal Study for Schizophrenia by Sensky (2000)?
- Patients had same time allocation at the same intervals as the patients in the CBT
- Therapists were empathetic + non-directive
- No attempt at therapy, the sessions focused on hobbies, sports + current affairs
What was the Procedure for Assessing the Patients of the Longitudinal Study for Schizophrenia by Sensky (2000)?
- Assessed by blind raters at baseline, after treatment (lasting up to 9 months), and a 9 month follow-up evaluation
- Assessed using comprehensive psychiatric rating scale, the scale for assessment of negative symptoms and a depression rating scale
- Patients continued to received routine care throughout the study
- Patients received a mean of 19 individual treatment sessions over 9 months
What does Diagnosis Involve?
- Clinician assessing a patient •Decides whether they show evidence of mental disorder
- Decides whether their symptoms match those in a checklist of the features + symptoms of a mental disorder
Why is it Hard to Define Abnormal Behaviour in an Objective and Scientific Way?
- No clear dividing line separating normal + abnormal behaviour
- Concept of abnormality can change over time
- Concept of abnormality can change between societies/cultures
- Many different types of behaviour can be considered abnormal
What are the 4 D’s of Diagnosis?
- Deviance
- Distress
- Dysfunction
- Danger
What is Deviance as 1 of the 4 D’s of Diagnosis?
- Behaviours/emotions that are unusual in society
* Behaviour must be statistically rare + disapproved of by most in society
What is Distress as 1 of the 4 D’s of Diagnosis?
Extent to which the individual finds their behaviour and/or emotions upsetting
What is Dysfunction as 1 of the 4 D’s of Diagnosis?
Extent to which the behaviour interferes with the persons day-to-day life
What is Danger as 1 of the 4 D’s of Diagnosis?
Behaviour which could harm others or the individual
What is the Issue and Debate of Issues of Social Control in the Diagnosis of Mental Disorders?
- Clinicians have a lot of power and influence in the diagnosing of mental health problems
- This has implications for patients who are labelled as mentally ill
- As it’s possible to treat patients against their will if their sectioned by the mental health act + considered at risk to themselves or others
- But, antipsychotic medication is critical for alleviating the distress associated with schizophrenia + enabling quality of life to be restored
What are the Strengths of the 4 D’s of Diagnosis?
- Useful - they have practical applications in helping professionals decide whether a patient symptoms need a clinical diagnosis
- Holistic way to assess someone’s mental health - cover a wide range of symptoms
- Davis (2009) - suggests a 5th D needs to be added - duration to increase validity
What are the Weaknesses of the 4 D’s of Diagnosis?
- Low validity - as diagnosis may not be accurate
- Low reliability - if used by 2 professionals, may not get same diagnosis - reducing scientific status of diagnosis
- Subjectivity in the application of the 4 D’s - E.g. dysfunction is subjective as individual may not think they have a problem + their unusual behaviour may suit them
- Distress + danger is subjective + difficult to measure - not all mental disorders are distressing
- Model criticised for being incomplete - Davis (2009) suggests that duration needs to be added
What is the Issue and Debate of Practical Issues in the Design and Implementation of Research in the Diagnosis of Mental Disorders?
- Issues of reliability + validity- diagnosis process conducted through unstructured or semi-structured interviews
- When gathering highly sensitive data about someone’s mental health - there are problems with the self-report method
What is the Issue and Debate of Psychology as a Science in the Diagnosis of Mental Disorders?
- Diagnosing disorders relies on unstructured/semi-structured interviews
- Involving the clinicians subjective interpretation of data
- Which reduces scientific status of the diagnosing of mental illness as it’s objective, lacks reliability and validity
Why are Classification Systems used by Practitioners?
To help them make diagnosis + establish appropriate treatment regimes
What is the Aim of Classification Systems?
Provide clear + measurable criteria for diagnosis, which can be used in the same way by all practitioners - increasing the reliability of diagnosis
What is the Medical Model of Abnormality?
- Biological approach assuming that the major source of abnormal behaviour is a form of medical illness
- Believes that the best treatment for mental disorders is biological - e.g. drug treatment
What are the Strengths of the Medical Model of Abnormality?
- Scientific + objective approach to diagnosis - has a lot of scientific credibility
- It group symptoms together + classifies them into a syndrome - so, their cause can be discovered + treated
What are the Limitations of the Medical Model of Abnormality?
- Limited - criticised for just focusing on the symptoms + not causes of this disorder - e.g. the model was criticised by anti-psychiatry movement in the 1960s
- Symptoms cannot be easily measured, so clinician must make a subjective judgement
What was the Anti-Psychiatry Movement in the 1960’s which Criticised the Medical Model of Abnormality?
- Thomas Szasz + R.D. Laing suggested that psychiatric symptoms is an understandable reaction to coping with a sick society
- They felt that mental hospitals were not designed to cure people + they function as a prison, where disruptive people could be removed from society
- Concerned that diagnosis could be used as an agent of state control + diagnosis results in labelling + could be used to medicalise social problems
- Concerned about controversial medical practices in psychiatry - e.g. use of lobotomies as a treatment
What are the 2 Major Classification Systems?
- ICD 10
* DSM-5
What is the Purpose of the DSM-5 and the ICD 10?
- Diagnostic tool is designed to enable practitioners to identify + treat particular disorders
- To provide a standardised, criterion based system to allow for accurate diagnosis of mental disorders
Why are the DSM and ICD Regularly Reviewed and Updated?
- To take into account new research
- To take account of peoples changing cultural views
- To show that psychological understanding changes and develops over time
What are the Similarities Between the DSM and ICD?
- Both regularly updated
- Both attempt to make diagnosis accurate across cultures
- Both rely on checklists + can be criticised for being reductionist
- Both criticised as use the medical model
- Both designed to enable practitioners to identify + treat particular disorders
- Both include categories of mental disorders based on characteristic patterns of symptoms
What are the Differences Between the DSM and ICD?
- DSM less reductionist than ICD - so it’s more holistic than ICD
- ICD used in many countries in the world, but DSM used in America
- ICD is free + an open resource, but DSM generates profits for the American psychological Association
- DSM only deals w/ mental conditions, but ICD also diagnoses physical illness
What is the Issue and Debate of Reductionist vs Holistic in the Classification Systems?
- DSM and ICD rely on checklists
- Can be criticised for being reductionist
- But, DSM takes account of psychological factors + disability, so it’s less reductionist than the ICD
What is the Issue and Debate of How Psychological Understanding has Changed Over Time in the Classification Systems?
- Late 19th Century - Kraeplin argued that pychiatric disorders are physical in nature + should be studied as a branch of medical science + it is possible to classify specific mental health disorders by their symptoms, diagnose them + predict their course
- Both DSM + ICD are regularly updated
What is the Issue and Debate of Psychology as a Science in the Classification Systems?
- Reliable - rely on standardised checklists of observable behaviour - used in the same way by all clinicians
- But, there will always be an element of subjectivity when interpreting the diagnostic criteria
What is the Issue and Debate of Practical Issues in the Classification Systems?
- DSM +ICD are regularly updated
* So, they show that psychological understanding changes and develops over time
What is the Issue and Debate of Cultural Differences in the Classification Systems?
- DSM and ICD attempt to make diagnosis accurate across cultures
- But, some argue that they still have a western bias
When was the DSM 5 Published?
May 2013
What does the DSM-5 Assess Individuals In Terms Of?
- The type of disorder from which they suffer - e.g. psychotic disorders
- Psychological + contextual factors - as it can influence the well-being of the individual - e.g. unemployment
- Disability - looks at overall level of functioning of the individual
- Co-existing factors - e.g. medical conditions
What does the DSM-5 Assessment of an Individual Involve?
- Clinical interviews
- Observations of the client
- Medical records of the client
- Focuses on assessing patients along the spectrum
What is the Issue and Debate of Developmental Psychology in the Classification Systems?
- Latest version of DSM reflects developmental + lifespan considerations
- Reflects developmental processes that occur early in life (e.g. schizophrenia) and those that are more commonly developed during adolescence (e.g. depression)
- Highlighting understanding that some psychiatric illnesses occur during certain periods of our development
How does the DSM 5 Manual Divide into 3 Sections?
- 1 - Intro to manual w/ instructions on its use
- 2 - Contains classification of the main mental health disorders - e.g. OCD, schizophrenia, bipolar, anxiety, etc
- 3 - Contains other assessment measures to aid diagnosis - cultural formulation interview guide to help diagnose individuals from a different culture from the clinician + includes other conditions that are being assessed for possible future diagnosis
When is Diagnosis is Considered to be Reliable?
- If different practitioners arrive at same diagnosis of a patient
- When clinicians agree on a diagnosis there is high inter-rater reliability for the system of diagnosis
What is the Evidence from Spitzer and Williams (1985) that Suggests that Diagnosis is Low in Reliability?
- Reviewed process of diagnosis
* Suggested that experienced psychiatrists only agree on diagnosis about 50% of the time
What is the Evidence from Hiller et al (1992) that Suggests that Diagnosis is Low in Reliability?
Argued reliability is in doubt for some disorders related to schizophrenia
What is the Evidence from Brown (2002) that Suggests that Diagnosis is High in Reliability?
- Tested reliability + validity of DSM-5 diagnosis for anxiety + mood disorders
- Found them to be good to excellent
What is the Evidence from Jacobsen et al (2005) that Suggests that Diagnosis is High in Reliability?
- Through a random sample of Danish in-patients + outpatient’s w/ a history of schizophrenia
- Showed that ICD 10 is a reliable measure of schizophrenia + compares well in terms of reliability with the DSM-111-R
What is the Evidence from Pederson (2001) that Suggests that Diagnosis is High in Reliability?
- Found 71% of psychiatrists agreed with the ICD 10 definition of depression when assessing 116 patients
- This indicates high inter-rater reliability
What are the Improvements in Reliability of Diagnosis?
- Improved w/ the use of standardised interview schedules specifying symptoms to ask about + giving instructions as to how to rate their severity
- DSM + ICD have specific diagnostic operational criteria for diagnosis to increase objectivity + reliability - e.g. clear definitions are given for each disorder + a list of symptoms