clinical 7 Flashcards
when do you give thrombolylis in stroke
within 4.5 hours of onset of symptoms
once haemorrhage stroke has been ruled out
preventative drug given after an ischaemic stroke
clopidogrel
what do you give after an ischaemic stroke if clopidogrel is CI
aspirin plus modified release (MR) dipyridamole
facial nerve innervates what 4 areas
face - facial expression
ear - nerve to stapedius
taste - anterior 2/3rds
tear - lacrimal gland
Causes of bilateral facial nerve palsy (4)
sarcoidosis
Guillain-Barre syndrome
polio
Lyme disease
cholesterol level that requires statin after an ischaemic stroke
if more than 3.5
anti epileptic most associated with weight gain
sodium valproate
how does sodium valproate work
increases GABA activity
first line treatment for generalised seizures
sodium valproate
first line treatment for partial seizures
carbamazepine
second lin treatment for generalised if sodium valproate is not working
lamotrigine
carbamazepine may actually exacerbate ______ seizure
absent
frequency of migraine that requires prophylaxis
more than 2 a month
migraine prophylaxis in woman of child bearing age
propanolol
migraine prophylaxis in the with asthma
topiramate
drug that can be given as migraine prophylaxis
topiramate or propanolol
when do you give phenytoin
in status epileptics is continuing 10 mins after receiving diazepam or lorazepam
what can happen following a sub arachnoid haemorrhage
cerebral vasospasm
what do you give following a subarachnoid haemorrhage to prevent cerebral vasospasm
calcium channel blocker (ends in -pine)
if stroke due to a-fib, when do you start anticoagulation therapy (warfarin)
15 days after onset of symptoms
first line for spasticity in MS
baclofen or gabapentin
whig parkinson drugs make you lose impulse control
dopamine agonists
what is ‘anticipation’ in huntingtons
earlier onset in successive generations
drug that can cause parkinsinism
haloperidol (antipsychotic: decrease amount of dopamine, low dopamine associated with parkinson)
first line treatment for neuropathic pain
amitriptyline, duloxetine, gabapentin or pregabalin
first line treatment for trigeminal neuralgia
carmabazepine
bells palsy, what nerve
facial LMN