Clindamycin, Flagyl, & Fidaxomicin Flashcards
Tell me about the Lincomycin family and what drug is in it
What is the MOA for Clindamycin
What forms of drug resistance do bacteria have to this antibiotic
Describe to me the pharmacokinetics and dynamics of clindamycin and unique things about it
No renal adjustments needed
What is the clindamycin spectrum of activity?
What is a D test?
Positive D test means NOOOOO clinda like HELLLL NAH. STAPH IS RESISTANT
What are the ADRs to clindamycin
Tell me about Metronidazole
What is the MOA of metronidazole?
It is bacterialcidal btw
What constitutes a MTZ resistant and non resistant strain
How does energy production and resistance go hand and hand for MTZ?
What is the mechanism in which helicobacter pylori becomes resistant to metronidazole?
What is the spectrum of activity for metronidazole?
Tell me about the pharmacokinetics and dynamics of metronidazole
What are the ADRs to MTZ
What are some drug interactions and dosing of MTZ?
Describe this image
Interpret it, but basically we have gram neg and anaerobes in abdominal area (MTZ) and diaphragm is more upper area like clindamycin
Tell me about Fidaxomicin
What is Fidaxomicin’s mechanism of action and resistance
What is Fidaxomicin’s spectrum of activity ?
C. DIFFF BABBBYYYYYYYYYY YEAHHHHHH
what is fidaxomicin’s pharmacokinetic and pharmacodynamics?
NO RENAL ADJUST FOR RENAL IMPAIRMENT
GIMME THE ADRS to fidaxomicin
