C Diff Flashcards

1
Q

Tell me about the overall summary of C diff infection.

A
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2
Q

What is the pathogenesis of C diff

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3
Q

What is a microbiome?

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4
Q

Tell me about the risks of antibiotics in causing CDI

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4
Q

What does C diff even do?

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5
Q

What is the difference between colonization and infection?

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6
Q

What is the clinical presentation of CDI and the additional symptoms

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7
Q

What kind of stool do u get with c diff

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8
Q
A

D

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9
Q

Tell me about C diff lab test recommendations

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10
Q

Tell me about the CDI testing algorithm proposed by ACG

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11
Q

This is the UCI guideline algorithm for ur information

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12
Q

Tell me the classifications of CDI

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13
Q

Tell me about CDI treatment in adults

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14
Q

What antibiotics are used for treatment of CDI

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15
Q

Tell me about CDI initial treatment

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16
Q

Why is vancomycin PO preferred over Flagyl in CDI

A
17
Q

Tell me about Fidaxomicin vs Vancomycin

A
18
Q

Go more into detail about how vanco and fidaxomicin achieve similar clinical cure vs CDI

A
19
Q

What is the challenge of fidaxomicin?

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20
Q

What are some other treatment considerations for c diff?

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21
Q

What do I monitor for a response for CDI treatment?

A
22
Q
A

C and D

23
Q

What are the risk factors for recurrence of CDI (rCDI)

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24
Q

What is the treatment for rCDI?

A
25
Q

What is the fidaxomicin extended pulsed regimen

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26
Q

Tell me about a vancomycin taper

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27
Q

Tell me about the recurrence outcomes with vancomycin pulsed tapered regimen.

A
28
Q
A

C or D

E: Fidaxomicin 200 mg by mouth twice daily for 5 days then qod for 20 days

29
Q

What kind of drug is used as adjunctive treatment for c diff?

A

Monoclonal antiodies in this case Bezlotoxumab (zinplava)

30
Q

Tell me about Bezlotoxumab (zinplava)

A
31
Q

What are some other treatment options in literature for c diff

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32
Q

Tell me the treatment of second or subsequent CDI recurrence

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33
Q

What is a fecal microbiota transplant (FMT)

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34
Q

What is the efficacy of FMT?

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35
Q

What is live biotherapeutic products (LBPs)

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36
Q

Tell me about fecal microbiota, Live-Jslm (rebyota)

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37
Q

Tell me about fecal microbiota spores, live-brpk (FMSL) VOWST

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38
Q

How do i prevent C diff

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39
Q

Tell me the algorithm for cdiff treatment

A