Beta-Lactam Antibiotics: Cephalosporins, Carbapenems, and Monobactams Flashcards

1
Q

Tell me about the substitution sites when it comes to cephalosporins

A
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2
Q

Tell me the spectrum activity of cephalosporins (more second generations) give me their names and brand names

A
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2
Q

Tell me the spectrum activity of cephalosporins (first and second generations) give me their names and brand names

A
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3
Q

Tell me the spectrum activity of cephalosporins (third gen) give me their names and brand names

A
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4
Q

Tell me the spectrum activity of cephalosporins (one more third gen and 4th gen) give me their names and brand names

A
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5
Q

Tell me the spectrum activity of cephalosporins (5th gen) give me their names and brand names

A

No pseudomonas with teflaro but it works on MRSA

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6
Q

What is ESBL?

A

Extended spectrum beta lactamases (supppperrrr betalactamases man)

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7
Q

Tell me about the cephalosporins that are reserved for MDR-GNR

A
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8
Q

Go a little bit more into detail about fetroja and its MOA

A
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9
Q
A
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10
Q

What is the treatment principle for cephalosporins

A
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11
Q

Tell me about the pharmacokinetics (absorption)

A
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12
Q

Tell me about the pharmacokinetics (Distribution)

A
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13
Q

Tell me about the pharmacokinetics (Elimination)

A
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14
Q

Give me a summarization of the dosing for these medications of cephs

A
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14
Q

Summarize the charts about the pharmacokinetics for ceph drugs

A
14
Q

Tell me about the CLSI MIC breakpoints

A
15
Q
A
16
Q

Give me a general adverse effect profile for cephalosporins (1)

A
17
Q

Give me a general adverse effect profile for cephalosporins (2) ceftriaxone

A
18
Q

Give me a general adverse effect profile for cephalosporins (3) Cefepime

A
19
Q

Tell me about cross reactivity for cephs (1)

A
20
Q

What are the hypersensitivity rxns for ceph

A
21
Q

Tell me more about cross reactivity (2)

A
22
Q
A
23
Q
A
24
Q
A
25
Q

What are some drug interactions with cephalosporins

A
26
Q

Tell me about carbapenems and their therapeutic uses

A
27
Q

What is the spectrum of activity for carbapenems? (1) just a general overview

A
28
Q

What is the basic spectrum of activity for carbapenems? (2)

A
29
Q

Give me the spectrum activity for carbapenems (gram positive)

A
30
Q

Give me the spectrum activity for carbapenems (gram negative)

A
30
Q

Give me the spectrum activity for carbapenems (Anaerobes)

A
31
Q
A
32
Q

Tell me the pharmacokinetics and dosing of carbapenems

A
33
Q

What are the adverse effects of carbapenems?

A
34
Q

Describe the cross reactivity with penicillins and other drug interactions with carbapenems

A
35
Q

What monobactam do we have and how does it work?

A