Class 22 Flashcards
Systems Complications (Cardiovascular) Hypertension
→ result of combined effects of heart & blood vessel changes & lung, liver, kidney stresses
Systems Complications (Cardiovascular) Large Vessel Damage (diabetic macroangiopathy)
→ increased incidence of atherosclerosis
→ thickening from irritation/damage of vessel walls
(arteriosclerosis)
→ onion-skinning: recurrent internal scarring, from
high blood pressure & blood pH
Systems Complications (Cardiovascular) Small Vessel Damage (diabetic microangiopathy)
Hyalinization is form of tissue degeneration in which normal tissue components deteriorate & there is excess production of extracellular matrix. Result is homogeneous & glassy material. Arteriolar hyalinization is like onion skin lesion in arteries, forming in layers in tunica media (smooth muscle
layer) sometimes also endothelium basement membrane &/or adventitia layer. It results in reduced lumen size & loss of contraction/dilation capacity of vessel wall. Similar degenerative process can occur in cells of capillary walls, making them stiff & impenetrable, also resulting in poor myoepithelial response (ability to change size of pores between cells). Results in ↓tissue nutrition/function, ↑ TPR, edema.
Systems Complications (Cardiovascular) Heart Damage (overlaps with other vital organ stress)
→ heart wall perfusion is reduced
→ cardiac muscle glucose supply is compromised
→ coronary arteries strongly affected by atherosclerosis
→ heart is stressed by hypertension
→ body tissue needs lead to increased demands on heart
→ congestive heart failure develops
Systems Complications (Cardiovascular) Increased Risk of Infarction
→ tissue death due to loss of blood supply
→ can occur in various locations
→ diabetics have higher incidence of angina pectoris & heart attack, & TIAs & stroke than non-diabetics
Damage to cardiovascular system is now understood to start at __________________________.
prediabetes stage, so before diabetes diagnosis.
Up to 80% of people with diabetes die of ________________ (compared to 50% in the general population).
CV disease
After having stroke or heart attack, people with diabetes are at ↑’d risk of having ___________________ or __________________compared to non-diabetics. People with diabetes are also more likely to need an angioplasty.
second stroke or heart attack
Studies have shown that CV system of adults with Type 2 diabetes may have?
impaired ability to adapt to exercise. MRI scans showed that teens with Type 2 diabetes had hearts that did not expand & fill with blood to same capacity as those without diabetes. Teens were also shown to have less blood flow through femoral arteries.
Study at Heart & Diabetes Research Institute in Melbourne, Australia found correlation between?
insulin resistance & increased sympathetic nervous system activity. This is because of multiple changes in beta 2 & beta 3 adrenoceptor genes. SyNS activity accompanying insulin resistance is closely linked with left ventricular hypertrophy in patients with Type 2 diabetes, even those without high blood pressure.
After 10-15 years, all diabetics have ___________________________.
some degree of CV impairment
(Diabetes) Increased Risk of Gangrene
→ 100 times more likely to occur in diabetic
→ may develop from minor injury/wound
→ combined effects of poor tissue resilience, toxic conditions, impaired perfusion/ drainage, tendency to infection
→ risk of amputation, especially in lower limb
(Diabetes) Kidneys
→ high incidence of renal artery atherosclerosis
→ high incidence/recurrence of kidney infections & stones
→ adversely affected by hypertension
→ very damaged by diabetic micorangiopathy
→ their blood supply & nutrient supplies compromised
→ nephritic & nephrotic syndromes
→ glomerulonephron destruction
→ high incidence of kidney failure
(Diabetes) Vision
→ impaired eye tissue health, susceptibility
to infection, impaired extrinsic & intrinsic circulation
→ high incidence of microbleeds
→ potential for impaired neurological controls
→ increased incidence of cataracts &
glaucoma
→ vision impairment of some degree is typical
→ significant incidence of both legal & total
blindness
(Diabetes) Liver
→ extremely high workload under adverse conditions
→ blood supply, glucose & enzyme supplies compromised
→ adversely affected by hypertension
→ high incidence of liver damage
(Diabetes) Digestion
→ digestive problems show up pervasively
→ combinations of indicators of poor digestion & elimination, with nausea & diarrhea prominent
→ digestive structures can be uncomfortable, painful
(Diabetes) Skin
→ reduced cellular health/resilience
→ compromised local circulation, especially in extremities
→ increased susceptibility to bacterial & fungal infection
→ increased risk of injury due to sensory deficits
→ increasing tendency to breakdown, ulceration
Nervous System (Central Nervous System)
→ seizures (usually from non-compliant behaviour)
→ various impairments of body system controls
→ increased tendency to develop dementia
Nervous System (Peripheral Nervous System)
→ nerve damage is very common
→ paraesthesias & sensory loss (hypaesthesia, anaesthesia) are most common symptoms; most marked in extremities, especially feet (“sock & glove anaesthesia”)
→ neuropathic pain also common
→ motor weakness may also occur
Diabetes and Foot Care
Many people with diabetes have problems with their feet. Ask doctor to explain your risk factors for foot problems. Can prevent serious foot problems by following basic guidelines.
Diabetes and Foot Care: A Patient’s Checklist *DO…
…check feet every day for cuts, cracks, bruises, blisters, sores, infections, unusual markings
…use mirror to see bottom of feet if can’t lift them up
…check colour of legs & feet. If swelling, warmth or redness or if pain, see doctor or foot specialist right away
…clean cut or scratch with mild soap & water & cover with dry dressing for sensitive skin
…trim nails straight across
…wash & dry feet every day, especially between toes
…apply good skin lotion every day on heels & soles; wipe off any excess lotion
…change socks every day
…always wear good supportive shoe
…always wear professionally fitted shoes from reputable store; professionally fitted orthotics may help
…choose shoes with low heels (under 5 cm high)
…buy shoes in late afternoon (since feet swell slightly by then)
…avoid extreme cold & heat (including sun)
…exercise regularly
…see foot care specialist if need advice or treatment
Diabetes and Foot Care: A Patient’s Checklist *DO NOT…
…cut your own corns or calluses
…treat your own in-growing toenails or slivers with razor or scissors – see doctor or foot care specialist
…use over-the-counter medications to treat corns & warts – are dangerous for people with diabetes
…apply heat to your feet with hot water bottle or electric blanket – you could burn feet without realizing it
…soak feet
…take very hot baths
…use lotion between toes
…walk barefoot inside or outside
…wear tight socks, garters or elastics, or knee highs
…wear over-the-counter insoles – can cause blisters if not right for your feet
…sit for long periods of time
…smoke
Foot Care Issues/Adaptations
Keep in mind that massage therapist can play important role in helping monitor foot tissue, especially when sensation &/or vision impairments are present.
Stay alert for lesions, even minor, & adapt accordingly.
Use doctor-approved skin lotions/creams if indicated.
Remember tissue may be quite fragile to pressure & temp.
Hygienic practices at all times!
Take precautions related to decubitus ulcer risk (positions, pressure releases, adapt techniques, remove oil/lotion, don’t leave tissue wet); no onsite massage if red spot present.
Diabetes Case History Questions
• When were you diagnosed? How many years have you had diabetes?
• What type of diabetes do you have? Are you insulin dependent?
• Is there family history of diabetes?
• Have there been any major changes in your diabetes status?
• Has your diabetes usually been stable?
• Have you been compliant with medications & diet?
• Have you had any diabetic emergencies? What type? How recently? What cause(s)?
• Have you had any surgeries or amputations because of diabetes?
• How often are you checked medically? Last diabetes specialist appointment?