CKD 2

Question 1

Most target doses of Iron replacement

Answer 1

1000mg

Question 2

Oral iron therapy not on HD

Answer 2

Ferrous sulfate 325 mg PO BID

Question 3

What symptoms limits iron therapy

Answer 3

constipation and GI intolerance

Question 4

Parenteral iron preparations

Answer 4

iron dextran (INfed), Sodium ferric fluconate (Ferrlecit), Iron Sucrose (Venofer), Ferumoxytol (Feraheme)

Question 5

Iron dextran dose

Answer 5

500-1000 mg in 250 mL of NSS infused for 1 hour

Question 6

If a pt has trouble with iron replacement therapy they can use

Answer 6

maintenance therapy, 25-100 mg/week IVx10 weeks

Question 7

ADRs of parenteral iron preparations

Answer 7

flushing and dizziness are common, but hypotension is most significant

Question 8

Parenteral iron monitoring

Answer 8

every 3 months, serum iron, ferritin, tSat

Question 9

Parenteral iron total dose

Answer 9

200 mg IV daily x5, 200 mg IV every other day x5, 300 mg IV q3 days

Question 10

peritoneal dialysis

Answer 10

tube in peritoneal cavity drains toxins, new fluids drain into peritoneal cavity to start process over

Question 11

Indications for RRT

Answer 11

nausea, vomiting, poor nutrition, metabolic acidosis, lethargy/ malaise, worsening kidney function

Question 12

Best option for RRT

Answer 12

Transplant- far better outcomes, better if living donor

Question 13

Negatives of kidney transplant

Answer 13

risk for infection, bone loss, CVD, contraindicated if malignancy, infection, severe extra renal disease, illicit drug use