Cirrhosis Flashcards

1
Q

what is cirrhosis

A

Chronic degenerative disease of the liver

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2
Q

What occurs in cirrhosis

A

Lobes are covered with fibrous tissue, parenchyma degenerates and lobules are infiltrated with fat

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3
Q

what is micronodular cirrhosis a result of?

A

alcohol abuse

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4
Q

What is micronodular cirrhosis a result of?

A

Viral hepatitis or infection

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5
Q

what are essential features of cirrhosis?

A

Essential feature is simultaneous parenchymal necrosis, regeneration, and diffuse fibrosis, resulting in a disorganization of lobular architecture.

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6
Q

what are three classic cirrhosis symptoms

A

Hepatomegaly, jaundice, ascites

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7
Q

What are symptoms of acute cirrhosis

A

Asymptomatic or

Nausea, flatulence, ascites, light coloured stool, weakness, abdominal pain, varicosities, spider angiomas

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8
Q

what are symptoms of chronic cirrhosis

A

Nausea, anorexia, weight loss, jaundice, dark urine, fatigue, varicosities

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9
Q

Lab tests associated with cirrhosis

A
Increased ALK phos 
· Increased Direct Bilirubin 
· Increased AST
· Increased ALT 
· Increased Leukopenia
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10
Q

what is the first sonographic finding of cirrhosis

A

Hepatomegaly (Enlarged liver)

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11
Q

As cirrhosis increases, liver volume _______in the right lobe and _________ and ______ enlarges

A

Right lobe, left lobe, caudate lobe

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12
Q

what test can indicate of cirrhosis

A

Ratio of caudate lobe width to the right lobe width can be used to indicate cirrhosis (C/RL value of 0.65 is indicative of cirrhosis)

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13
Q

Is echogenicity decreased or increased?

A

Increased echogenicity and coarsening of the hepatic parenchyma secondary to fibrosis and surface nodularity

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14
Q

There is _________attenuation

A

Increased

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15
Q

there is __________vascular markings

A

Decreased

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16
Q

what may be present with ascites around the liver?

A

Hepatosplenomegaly

17
Q

what lobes may be atrophied?

A

Right and left medial

18
Q

what appearance occurs in chronic cirrhosis

A

Surface nodularity around the liver edge

19
Q

What are differential diagnosis of cirrhosis?

A

· Fatty Liver

· Hepatitis

20
Q

what are other causes of cirrhosis?

A

Other causes of cirrhosis include biliary cirrhosis, Wilson disease, primary sclerosing cholangitis, and hemochromatosis.