Chronic Liver Disease Flashcards
How is primary sclerosing cholangitis treated?
ERCP - stenting/ballooning
What are the 4 stages of Hep B infection?
Immune tolerance
Immune clearance
Immune control
Immune escape
What can precipitate encephalopathy?
Drugs - benzos, alcohol
Increased ammonia - GI bleeding, infection
Dehydration
TIPS
What causes the majority of liver cancer in Australia?
Viral hepatitis
What might the platelets be in chronic liver disease?
Lowered <200
What is the name of the tube used to occlude varices in acute bleeding?
Senstaken-Blakemore
What are the criteria that consititute the Child-Pugh score?
Ascites
Encephalopathy
INR
Albumin
Bilirubin
Parotidomegaly is specific to which type of chronic liver disease?
Alcoholic
When are the DDx for acute jaundice in someone with chronic liver disease?
Portal vein thrombosis
Acute obstruction of the biliary tree
Spontaneous bacterial peritonitis
What is the pathonemonic feature of hepatic failure?
Portosystemic encephalopathy
Which beta-blocker is used to treat varices?
Propranolol
How is primary biliary cirrhosis treated?
Urso-deoxycholic acid
How is autoimmune hepatitis treated?
Prednisolone
+/-
Azathioprine/Metacaptopurine
Outline the histological progression of fibrosis in cirrhosis
F1 - Periportal fibrosis
F2 - Periportal fibrosis with few septa
F3 - Numerous septa without architectural distortion
F4 - Architectural distortion and nodular formation
How long can you expect a liver transplant to last?
>20 years
